Luojing Chen, Ph.D.

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Current Appointments

• Research Assistant Professor - Department of Medicine (SMD)

Education
PhD Genetics	Iowa State University	1992
MS Microbiology	China-Wuhan University	1985
BS Biology	China-Wuhan University	1982

Post-Doctoral Training & Residency
Postdoctoral Fellow Signaling Transduction Lab Massachusetts General Hospital Harvard Medical School Charlestown, MA	1996 - 2000
Postdoctoral Fellow Molecular Biology Massachusetts General Hospital Harvard Medical School Boston, MA	1995 - 1996
Postdoctoral Fellow Genetics Department Iowa State University Ames, IA.	1992 - 1995

Lab Description

Dr. Chen's research interests involve B cell signaling pathways. Dr. Chen's laboratory is currentlyf ocusing on the role of PKK (a protein kinase) in lymphoma and lupus.

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Lab Website

http://www.urmc.rochester.edu/medicine/allergy/research/chenlab.cfm

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Recent Journal Articles
Showing the 5 most recent journal articles. (12 available)
Kim, S.W.; Oleksyn, D.; Rossi, R.M.; Jordan, C.; Sanz, I.; Chen, L.; Zhao, K. "Protein kinase C-associated kinase is required for NF-{kappa}B signaling and survival in diffuse large B-cell lymphoma cells". Blood 11 (2007): 1644-1653.
Lee SC; Bottaro A; Chen L; Insel RA. "Mad1 is a transcriptional repressor of Bcl-6." Molecular immunology. 2006; 43(12):1965-71. Epub 2006 Jan 19.
Moran ST; Haider K; Ow Y; Milton P; Chen L; Pillai S. "Protein kinase C-associated kinase can activate NFkappaB in both a kinase-dependent and a kinase-independent manner." The Journal of biological chemistry. 2003; 278(24):21526-33. Epub 2003 Apr 03.
Cariappa A; Chen L; Haider K; Tang M; Nebelitskiy E; Moran ST; Pillai S. "A catalytically inactive form of protein kinase C-associated kinase/receptor interacting protein 4, a protein kinase C beta-associated kinase that mediates NF-kappa B activation, interferes with early B cell development." Journal of immunology (Baltimore, Md. : 1950). 2003; 171(4):1875-80.
Chen, L.; Haider, K.; Cariappa, A.; Rowitch, D.; Pillai, S. "PKC associated kinase (PKK), a novel membrane-associated, ankyrin repeat containing protein kinase". Journal of Biological and Chemistry 276 (2001): 21737-21744.