Sean D. Hurley, Ph.D.

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Current Appointments

• Research Assistant Professor - Department of Neurobiology and Anatomy (SMD)

Education
PhD Neuroscience	University of Florida	1997
BS Neurobiology	University of Florida	1992

Post-Doctoral Training & Residency
Postdoctoral Fellow, Department of Neurobiology and Anatomy, University of Rochester Medical Center. Supervisors: Dr. John A. Olschowka, Ph.D.; Dr. M. Kerry O'Banion, M.D., Ph.D. Analysis of aging's complex interaction with severity of neuroinflammation following injury; stereological analyses of neuroinflammation following CNS viral-vector gene therapy; development of immunohistochemical protocols; studies on the roles of cyclooxygenase in human neurological disease.	2000 - 2001
Postdoctoral Trainee, Neurobiology of Aging Training Grant, lzheimer's Disease Center, University of Rochester Medical Center. Supervisor: Dr. Paul D. Coleman, Ph.D. Laser capture microdissection for selective RNA analyses; studies on the interrelationship between aging and brain injury.	1998 - 2000
Postdoctoral Research Associate, University of Florida Brain Institute. Supervisor: Dr. Wolfgang J. Streit, Ph.D. Semi-quantitative RT-PCR analyses of cytokine and growth factor mRNAs following experimental models of brain injury.	1997 - 1998

Recent Journal Articles
Showing the 5 most recent journal articles. (16 available)
Lioy DT; Sheridan PA; Hurley SD; Walton JR; Martin AM; Olschowka JA; Moynihan JA. "Acute morphine exposure potentiates the development of HSV-1-induced encephalitis." Journal of neuroimmunology. 2006; 172(1-2):9-17. Epub 2005 Dec 02.
Maida ME; Hurley SD; Daeschner JA; Moore AH; O'Banion MK. "Cytosolic prostaglandin E2 synthase (cPGES) expression is decreased in discrete cortical regions in psychiatric disease." Brain research. 2006; 1103(1):164-72. Epub 2006 Jun 27.
Dietrich J; Blumberg BM; Roshal M; Baker JV; Hurley SD; Mayer-Pröschel M; Mock DJ. "Infection with an endemic human herpesvirus disrupts critical glial precursor cell properties." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004; 24(20):4875-83.
Olschowka JA; Bowers WJ; Hurley SD; Mastrangelo MA; Federoff HJ. "Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS." Molecular therapy : the journal of the American Society of Gene Therapy. 2003; 7(2):218-27.
Hurley SD; Coleman PD. "Facial nerve axotomy in aged and young adult rats: analysis of the glial response." Neurobiology of aging. 2003; 24(3):511-8.