Jeffrey M. Purkerson, Ph.D.

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Contact

University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 777
Rochester, New York 14642

Office: 585 273-3974

Portrait

Dr. Purkerson's research interests are:

1) Cell biology and physiology of the carbonic anhydrases

2) The response of renal epithelial cells to acid-base disturbances or injury.

Specialty

Nephrology

Current Appointments

Education
PhD Pharmacology University of Virginia 1991
BS Biochemistry California Polytechnic State University 1986
Post-Doctoral Training & Residency
Molecular Genetics and Microbiology Postdoctoral Fellowship, University of Massachusetts Medical Center, Worcester, MA 1994 - 1995
Immunoinflammatory Diseases Research Postdoctoral Fellowship, Searle Research and Development, Monsanto Company, University of Massachusetts, Worcester, MA 1991 - 1993
Fellowship Awards
Postdoctoral Fellowship, Arthritis Foundation: Regulation of Ig class switching and Ig secretion during productive and nonproductive T:B collaboration 1995 - 1998
Recent Journal Articles
Showing the 5 most recent journal articles. (19 available)
Peng H, Vijayakumar S, Schiene-Fischer C, Li H, Purkerson JM, Malesevic M, Liebscher J, Al-Awqati, Schwartz GJ. "Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation." Journal of Biological Chemistry. 284(10) (2009): 6465-75.
Peng H; Vijayakumar S; Schiene-Fischer C; Li H; Purkerson JM; Malesevic M; Liebscher J; Al-Awqati Q; Schwartz GJ. "Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation." Journal of Biological Chemistry 284(10) (2008): 6465-75.
Purkerson JM; Kittelberger AM; Schwartz GJ. "Basolateral carbonic anhydrase IV in the proximal tubule is a glycosylphosphatidylinositol-anchored protein." Kidney international. 2007; 71(5):407-16. Epub 2007 Jan 17.
Tsuruoka S; Watanabe S; Purkerson JM; Fujimura A; Schwartz GJ. "Endothelin and nitric oxide mediate adaptation of the cortical collecting duct to metabolic acidosis." American journal of physiology. Renal physiology. 2006; 291(4):F866-73. Epub 2006 May 16.
Purkerson JM; Schwartz GJ. "Expression of membrane-associated carbonic anhydrase isoforms IV, IX, XII, and XIV in the rabbit: induction of CA IV and IX during maturation." American journal of physiology. Regulatory, integrative and comparative physiology. 2005; 288(5):R1256-63.