Paul Spencer Brookes, Ph.D.

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Contact

University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 604
Rochester, New York 14642

Portrait

Current Appointments

Education
PhD Biochemistry UK-Cambridge U Med Sch 1997
BS Biochemistry UK - Non-Medical School 1993
Fellowship Awards
Post-Doctoral Fellowship Award ($60,000) AHA Southeast Affiliate 100% Effort "Mitochondria and NO• in cardiac hypertrophy" 1999 - 2001
DEPARTMENT OF PATHOLOGY, UNIVERSITY OF ALABAMA AT BIRMINGHAM, USA Post-doctoral Fellow (with Prof. VM Darley-Usmar & Dr. PG Anderson) 1998 - 2001
INSTITUTE OF NEUROLOGY, UNIVERSITY COLLEGE LONDON, UK Post-doctoral Fellow (with Prof. JB Clark & Dr. SJR Heales) 1997 - 1998
Postdoctoral Fellowship, American Heart Association, Southeast Affiliate 1999
Recent Journal Articles
Showing the 5 most recent journal articles. (38 available)
Tompkins AJ; Burwell LS; Digerness SB; Zaragoza C; Holman WL; Brookes PS. "Mitochondrial dysfunction in cardiac ischemia-reperfusion injury: ROS from complex I, without inhibition." Biochimica et biophysica acta. 2006; 1762(2):223-31. Epub 2005 Oct 21.
Burwell LS; Nadtochiy SM; Tompkins AJ; Young S; Brookes PS. "Direct evidence for S-nitrosation of mitochondrial complex I." The Biochemical journal. 2006; 394(Pt 3):627-34.
Nadtochiy SM; Tompkins AJ; Brookes PS. "Different mechanisms of mitochondrial proton leak in ischaemia/reperfusion injury and preconditioning: implications for pathology and cardioprotection." The Biochemical journal. 2006; 395(3):611-8.
Brookes PS; Freeman RS; Barone MC. "A shortcut to mitochondrial signaling and pathology: a commentary on "Nonenzymatic formation of succinate in mitochondria under oxidative stress"." Free radical biology & medicine. 2006; 41(1):41-5. Epub 2006 Apr 01.
Brookes PS. "Mitochondrial H(+) leak and ROS generation: an odd couple." Free radical biology & medicine. 2005; 38(1):12-23.