Haodong Xu, M.D., Ph.D.

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Contact

University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 626
Rochester, New York 14642

Office: 585 275-0857

Fax: 585 273-3637

Portrait

My research is focused on delineating the mechanisms in the regulation of voltage-gated potassium channels underlying the cardiac repolarization. Ongoing studies are focused on defining the functional roles of filamin C, an actin binding protein, in the regulation of both voltage-gated potassium channels and cardiac contraction. In addition, my interests also include molecular mechanisms of lung tumor and fibrosing interstitial pneumonia.

Current Appointments

Education
PhD Cardiac Physiology Soochow University Medical School 1993
MS Circulation Physiology Soochow University Medical School 1990
MD Medicine Soochow University Medical School 1987
Post-Doctoral Training & Residency
Fellow, Department of Pulmonary and Mediastinal Pathology, Armed Forces Institute of Pathology, Washington D.C. 2003 - 2004
Resident in Anatomic Pathology, Department of Pathology, Washington University School of Medicine, St. Louis, MO 2002 - 2003
Resident in Anatomic Pathology, Department of Pathology, Washington University School of Medicine, St. Louis, MO 2002 - 2003
Resident and Post-doctoral Research Fellow, Department of Pathology, Washington University School of Medicine, St. Louis, MO. Research area: Functions of KChIP2 and Filamin C in the Generation of Voltage-Gated Potassium Channels in Mouse Ventricular Myocytes 2001 - 2002
Resident in Anatomic Pathology, Department of Pathology, Washington University School of Medicine, St. Louis, MO 1999 - 2001
Postdoctoral Fellow, Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO 1993 - 1999
Research Fellow, Department of Cardiology, First Affiliated Hospital, Soochow University, Medical School, P. R. China 1993 - 1993
Research Fellow, Department of Cardiology, First Affiliated Hospital, Soochow University, Medical School, P. R. China 1990 - 1990
Fellowship Awards
NIH Cardiovascular Training Grant 2001 - 2002
NIH Cardiovascular Training Grant 1997 - 1999
Board Certifications
American Board of Pathology, Certification in Anatomic Pathology 2003
Recent Journal Articles
Showing the 5 most recent journal articles. (47 available)
Simon RA; di Sant'Agnese PA; Huang LS; Xu H; Yao JL; Yang Q; Liang S; Liu J; Yu R; Cheng L; Oh WK; Palapattu GS; Wei J; Huang J. "CD44 expression is a feature of prostatic small cell carcinoma and distinguishes it from its mimickers." Human pathology. 2009; 40(2):252-8. Epub 2008 Oct 05.
Pryor JG; Simon RA; Bourne PA; Spaulding BO; Scott GA; Xu H. "Merkel cell carcinoma expresses K homology domain-containing protein overexpressed in cancer similar to other high-grade neuroendocrine carcinomas." Human pathology. 2009; 40(2):238-43. Epub 2008 Oct 05.
Fallone E; Bourne PA; Watson TJ; Ghossein RA; Travis WD; Xu H. "Ectopic (mediastinal) parathyroid adenoma with prominent lymphocytic infiltration." Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry. 2009; 17(1):82-4.
Köbel M; Xu H; Bourne PA; Spaulding BO; Shih IeM; Mao TL; Soslow RA; Ewanowich CA; Kalloger SE; Mehl E; Lee CH; Huntsman D; Gilks CB. "IGF2BP3 (IMP3) expression is a marker of unfavorable prognosis in ovarian carcinoma of clear cell subtype." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2009; 22(3):469-75. Epub 2009 Jan 09.
Miyamoto H; Jones CE; Raymond DP; Wandtke JC; Strang JG; Bourne PA; Bonfiglio TA; Xu H. "Pulmonary metastases from uterine neoplasms after long tumour-free interval: four cases and review of the literature." Pathology. 2009; 41(3):234-41.