Hani A. Awad, Ph.D.

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My research focuses primarily on Musculoskeletal Tissue Engineering with an emphasis on challenging clinical problems and translational solutions.

Our approach is to develop in vivo and in vitro models of musculoskeletal injury and clinically-translatable outcome measures to assess the efficacy of regenerative and tissue engineering solutions.

Current research projects include:

1. Tissue Engineering of Massive Bone Allograft Union

2. Allografts and Gdf5 Gene Therapy in Flexor Tendon Tissue Engineering

3. Modulating Stem Cell Differentiation using Novel Allograft Scaffolds for Cartilage Repair

4. Fashioning a Superficial Zone-Like Layer in Bioreactor-Cultivated Tissue Engineered Cartilage

5. Evaluating models of human musculoskeletal disease and trauma

Current Appointments

• Assistant Professor - Department of Biomedical Engineering (SMD)
• Assistant Professor - Center for Musculoskeletal Research (SMD)
• Assistant Professor - Department of Orthopaedics (SMD)

Education
PhD Engineering Mechanics/Biomechanics	University of Cincinnati	1999
MS Engineering Mechanics/Biomechanics	University of Cincinnati	1995
BS Mechanical Engineering	University of Jordan	1993

Post-Doctoral Training & Residency
Bioengineering Laboratory (Mentor: Farshid Guilak), Department of Surgery - Division of Orthopaedic Surgery, Duke University	2000 - 2004

Fellowship Awards
Summer Research Fellowship, University of Cincinnati	1994
University Graduate Scholarship, University of Cincinnati	1993 - 1998

Lab Description

My Laboratory interfaces Biomedical Engineering and Orthopaedics. We provide opportunities for state of the art training related to Tissue Engineering and Biomechanics.

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Lab Website

http://www.urmc.rochester.edu/labs/awad-lab/

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Recent Journal Articles
Showing the 5 most recent journal articles. (41 available)
Tsutsumi,R.; Hock,C.; Bechtold,C. D.; Proulx,S. T.; Bukata,S. V.; Ito,H.; A Awad,H.; Nakamura,T.; O'Keefe,R. J.; Schwarz,E. M.;. "Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT". J.Orthop.Res. (2008).
Loiselle,A. E.; Bragdon,G. A.; Jacobson,J. A.; Hasslund,S.; Cortes,Z. E.; Schwarz,E. M.; Mitten,D. J.; Awad,H. A.; O'Keefe,R. J.;. "Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression". J.Orthop.Res. (2008).
Naik,A. A.; Xie,C.; Zuscik,M. J.; Kingsley,P.; Schwarz,E. M.; Awad,H.; Guldberg,R.; Drissi,H.; Puzas,J. E.; Boyce,B.; Zhang,X.; O'Keefe,R. J.;. "Reduced COX-2 Expression in Aged Mice is Associated with Impaired Fracture Healing". J.Bone Miner.Res. (2008).
Reynolds,D. G.; Shaikh,S.; Papuga,M. O.; Lerner,A. L.; O'Keefe,R. J.; Schwarz,E. M.; Awad,H. A.;. "Micro-CT-Based Measurement of Cortical Bone Graft-to-Host Union". J.Bone Miner.Res. (2008).
Li D; Gromov K; Søballe K; Puzas JE; O'Keefe RJ; Awad H; Drissi H; Schwarz EM. "Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity." Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2008; 26(1):96-105.