Tzong-jen Sheu, Ph.D.

See information for Patients. Viewing information for Researchers.

Current Appointments

• Senior Instructor - Department of Orthopaedics, Center for Musculoskeletal Research (SMD)

Education
PhD Molecular Biology	Univ Rochester Sch Med/Dent	2002
MS Toxicology	Taiwan-National Taiwan Univ, Taipei	1994
BS Public Health	Taiwan-National Taiwan Univ, Taipei	1992

Lab Description

The Center for Musculoskeletal Research houses nearly 70 MD and PhD researchers and graduate and post-doctoral students. This team has been the top orthopaedics lab in the United States since 2006.

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Lab Website

http://www.urmc.rochester.edu/ortho/research/index.cfm

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Recent Journal Articles
Showing the 5 most recent journal articles. (18 available)
Chen M; Zhu M; Awad H; Li TF; Sheu TJ; Boyce BF; Chen D; O'Keefe RJ. "Inhibition of beta-catenin signaling causes defects in postnatal cartilage development." Journal of cell science. 2008; 121(Pt 9):1455-65. Epub 2008 Apr 08.
Brouxhon S; Konger RL; VanBuskirk J; Sheu TJ; Ryan J; Erdle B; Almudevar A; Breyer RM; Scott G; Pentland AP. "Deletion of prostaglandin E2 EP2 receptor protects against ultraviolet-induced carcinogenesis, but increases tumor aggressiveness." The Journal of investigative dermatology. 2007; 127(2):439-46. Epub 2006 Sep 14.
Chen M; Lichtler AC; Sheu TJ; Xie C; Zhang X; O'Keefe RJ; Chen D. "Generation of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase." Genesis (New York, N.Y. : 2000). 2007; 45(1):44-50.
Li TF, Chen D, Wu Q, Chen M, Sheu TJ, Schwarz EM, Drissi H, Zuscik M, O'Keefe RJ. "Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes." J Biol Chem. 281 (2006): 296-304.
Li TF; Chen D; Wu Q; Chen M; Sheu TJ; Schwarz EM; Drissi H; Zuscik M; O'Keefe RJ. "Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes." The Journal of biological chemistry. 2006; 281(30):21296-304. Epub 2006 May 10.