David N. Hackney, M.D.
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Contact
University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 668
Rochester, New York 14642
Fax: 585 256-1416
Dr. Hackney's research interests are in spontaneous preterm birth as well as hematologic changes and disorders during pregnancy, with a focus on preterm labor secondary to chorion-decidual bleeding. Both basic science and clinical research endeavors are actively pursued. In the laboratory, Dr. Hackney's interest is in the role of protease-activated receptors in gestational tissues and how these may instigate membrane rupture or labor in the setting of intrauterine bleeding. Clinical projects include evaluating placental thrombotic disorders and peripheral maternal markers of thrombin activation in the context of adverse obstetrical outcomes. Dr Hackney's interests also include the genetic basis of thrombotic and hemmorhagic events during pregnancy, including the exploration of coagulation cascade polymorphisms other then previously characterized thrombophilias.
Current Appointments
- Assistant Professor - Department of Obstetrics and Gynecology (SMD)
| Education | ||
|---|---|---|
| MS Clinical Research | University of Pittsburgh School of Medicine | 2008 |
| MD Medicine | Univ Pittsburgh Sch Medicine | 2000 |
| BA Chemistry | Carnegie-Mellon Univ | 1996 |
| Post-Doctoral Training & Residency | |
|---|---|
| University of Pittsburgh Clinical Research Training Program Masters of Science in Clinical Research Translational Research Tract Pittsburgh, PA | 2006 - 2008 |
| University of Pittsburgh School of Medicine Magee-Womens Hospital Pittsburgh, PA Fellowship, Maternal-Fetal Medicine | 2005 - 2008 |
| Ohio State University Medical Center Department of Obstetrics and Gynecology Columbus, OH Internship and residency | 2000 - 2004 |
| Recent Journal Articles |
|---|
| Showing the 5 most recent journal articles. (7 available) |
| Hackney, DN; Chiao, JP; Macpherson, TA; Simhan, HN. "First trimester maternal concentrations of thrombin-inhibitor complexes and the presence of histologic placental lesions at delivery". J Matern Fetal Neonatal Med (2009). |
| Hackney DN; Dunigan JT; Simhan HN. "Maternal and fetal C-reactive protein genotype and first trimester CRP concentrations in maternal plasma." Journal of reproductive immunology. 2008; 79(1):44-9. Epub 2008 Sep 20. |
| Hackney DN; Macpherson TA; Dunigan JT; Simhan HN. "First-trimester maternal plasma concentrations of C-reactive protein in low-risk patients and the subsequent development of chorioamnionitis." American journal of perinatology. 2008; 25(7):407-11. |
| Catov JM; Bodnar LM; Hackney D; Roberts JM; Simhan HN. "Activation of the fibrinolytic cascade early in pregnancy among women with spontaneous preterm birth." Obstetrics and gynecology. 2008; 112(5):1116-22. |
| Hackney DN; Creinin MD; Simhan HN. "Medical Management of Early Pregnancy Failure in a Patient with Coronary Artery Disease." Fertil Steril (2007): 212.e1-3. |
