Troy Douglas Randall, Ph.D.
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Contact
University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 695
Rochester, New York 14642
Office: 585 276-4613
Lab: 585 273-3279
Fax: 585 442-3214
Dr. Randall is studying the development of local lymphoid tissues in the respiratory tract and determining how these tissues function to regulate respiratory immune responses. These tissues include the Bronchus Associated Lymphoid Tissue (BALT) and the Nasal Associated Lymphoid Tissue (NALT), which are found in the lungs and nasal passages respectively. Importantly, both BALT and NALT regulate different aspects of respiratory immunity in the context of allergy, asthma, respiratory infection and vaccination. Thus, Dr. Randall is defining the cellular and molecular mechanisms behind these differences.
Current Appointments
- Professor - Department of Medicine (SMD)
- Professor - Department of Microbiology and Immunology (SMD)
| Education | ||
|---|---|---|
| PhD Microbiology and Immunology | Duke University | 1992 |
| BS Chemistry | University of Denver | 1987 |
| Post-Doctoral Training & Residency | |
|---|---|
| Postdoctoral Fellow with Dr. Irving Weissman Stanford University | 1992 - 1996 |
| Postdoctoral Fellow with Dr. Ronald Corley Duke University | 1992 - 1992 |
| Predoctoral Fellow with Dr. Ronald Corley Duke University | 1987 - 1992 |
| Fellowship Awards | |
|---|---|
| Helen Hay Whitney Postdoctoral Fellowship Stanford University | 1993 - 1996 |
| NIH Postdoctoral Fellowship in Immunology Stanford University | 1992 - 1993 |
| NIH predoctoral training fellowship in Genetics Duke University | 1987 - 1990 |
Lab Description
The lab is studying the development of BALT and NALT to determine how these tissues function to regulate immune responses in allergy, asthma, respiratory infection and vaccination.
Lab Website
http://dev.mc.rochester.edu/medicine/allergy/research/RandallLab.cfm
| Recent Journal Articles |
|---|
| Showing the 5 most recent journal articles. (60 available) |
| Anolik JH; Looney RJ; Lund FE; Randall TD; Sanz I. "Insights into the heterogeneity of human B cells: diverse functions, roles in autoimmunity, and use as therapeutic targets." Immunologic research. 2009; Epub 2009 Apr 07. |
| Rangel-Moreno J; Moyron-Quiroz JE; Carragher DM; Kusser K; Hartson L; Moquin A; Randall TD. "Omental Milky Spots Develop in the Absence of Lymphoid Tissue-Inducer Cells and Support B and T Cell Responses to Peritoneal Antigens." Immunity. 2009; Epub 2009 May 06. |
| Randall, T.D.; Carragher, D.M.; Rangel-Moreno, J. "Development of secondary lymphoid organs". Ann Rev Immunol 26 (2008): 627-650. |
| Rangel-Moreno J; Carragher DM; Misra RS; Kusser K; Hartson L; Moquin A; Lund FE; Randall TD. "B cells promote resistance to heterosubtypic strains of influenza via multiple mechanisms." Journal of immunology (Baltimore, Md. : 1950). 2008; 180(1):454-63. |
| Carragher DM; Rangel-Moreno J; Randall TD. "Ectopic lymphoid tissues and local immunity." Seminars in immunology. 2008; 20(1):26-42. Epub 2008 Feb 19. |
