Lei Xu, Ph.D.

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Contact

University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 633
Rochester, New York 14642

Office: 585 273-1302 (primary)

Lab: 585 273-2415

Fax: 585 273-1450

Portrait

Current Appointments

Education
Ph.D. Biological Sciences Indiana University 2000
B.S. Biochemistry Nanjing University 1994
Post-Doctoral Training & Residency
Massachusetts Institute of Technology, Cancer Biology (Mentor: Richard Hynes) 2000 - 2007

Lab Website

http://www.urmc.rochester.edu/biomedical-genetics/faculty/xu-lab.cfm


Recent Journal Articles
Showing the 5 most recent journal articles. (8 available)
Shihong Li; Zhaohui Jin; Samir Koirala; Lihong Bu; Lei Xu; Richard O. Hynes; Chrisopher A. Walsh; Gabriel Corfas; Xianhua Piao. "GPR56 Regulates Pial Basement Membrane Integrity and Cortical Lamination". J. Neurosciences 28 (2008): 5817-5826.
Xu L; Shen SS; Hoshida Y; Subramanian A; Ross K; Brunet JP; Wagner SN; Ramaswamy S; Mesirov JP; Hynes RO. "Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases." Molecular cancer research : MCR. 2008; 6(5):760-9.
Xu L; Hynes RO. "GPR56 and TG2: possible roles in suppression of tumor growth by the microenvironment." Cell cycle (Georgetown, Tex.). 2007; 6(2):160-5. Epub 2007 Jan 28.
Xu L; Begum S; Hearn JD; Hynes RO. "GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis." Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(24):9023-8. Epub 2006 Jun 06.
Xu L; Fong Y; Strome S. "The Caenorhabditis elegans maternal-effect sterile proteins, MES-2, MES-3, and MES-6, are associated in a complex in embryos." Proceedings of the National Academy of Sciences of the United States of America. 2001; 98(9):5061-6.