Stephen R. Hammes, M.D., Ph.D.

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Journal Articles
Showing 38 journal articles currently available.
Ghayee HK; Havekes B; Corssmit EP; Eisenhofer G; Hammes SR; Ahmad Z; Tessnow A; Lazúrová I; Adams KT; Fojo AT; Pacak K; Auchus RJ. "Mediastinal paragangliomas: association with mutations in the succinate dehydrogenase genes and aggressive behavior." Endocrine-related cancer. 2009; 16(1):291-299. Epub 2008 Dec 15.
Grasfeder LL; Gaillard S; Hammes SR; Ilkayeva O; Newgard CB; Hochberg RB; Dwyer MA; Chang CY; McDonnell DP. "Fasting-induced hepatic production of DHEA is regulated by PGC-1{alpha}, ERR{alpha} and HNF4{alpha}" Molecular endocrinology (Baltimore, Md.). 2009; Epub 2009 Apr 23.
Deng J; Lang S; Wylie C; Hammes SR. "The Xenopus laevis isoform of G protein-coupled receptor 3 (GPR3) is a constitutively active cell surface receptor that participates in maintaining meiotic arrest in X. laevis oocytes." Molecular endocrinology (Baltimore, Md.). 2008; 22(8):1853-65. Epub 2008 May 29.
Evaul K; Hammes SR. "Cross-talk between G protein-coupled and epidermal growth factor receptors regulates gonadotropin-mediated steroidogenesis in Leydig cells." The Journal of biological chemistry. 2008; 283(41):27525-33. Epub 2008 Aug 13.
Deng J; Carbajal L; Evaul K; Rasar M; Jamnongjit M; Hammes SR. "Nongenomic steroid-triggered oocyte maturation: Of mice and frogs." Steroids. 2008; Epub 2008 Nov 24.
Carbajal L; Deng J; Dressing GE; Hagan CR; Lange CA; Hammes SR. "Meeting review: Extra-nuclear steroid receptors-Integration with multiple signaling pathways." Steroids. 2008; Epub 2008 Nov 27.
Li S; Lu MM; Zhou D; Hammes SR; Morrisey EE. "GLP-1: a novel zinc finger protein required in somatic cells of the gonad for germ cell development." Developmental biology. 2007; 301(1):106-16. Epub 2006 Aug 11.
Evaul K; Jamnongjit M; Bhagavath B; Hammes SR. "Testosterone and progesterone rapidly attenuate plasma membrane Gbetagamma-mediated signaling in Xenopus laevis oocytes by signaling through classical steroid receptors." Molecular endocrinology (Baltimore, Md.). 2007; 21(1):186-96. Epub 2006 Oct 04.
Lange CA; Gioeli D; Hammes SR; Marker PC. "Integration of rapid signaling events with steroid hormone receptor action in breast and prostate cancer." Annual review of physiology. 2007; 69():171-99.
Gill A; Hammes SR. "G beta gamma signaling reduces intracellular cAMP to promote meiotic progression in mouse oocytes." Steroids. 2007; 72(2):117-23. Epub 2006 Dec 18.
Hammes SR; Levin ER. "Extranuclear steroid receptors: nature and actions." Endocrine reviews. 2007; 28(7):726-41. Epub 2007 Oct 04.
Rasar MA; Hammes SR. "The physiology of the Xenopus laevis ovary." Methods in molecular biology (Clifton, N.J.). 2006; 322():17-30.
Jamnongjit M; Hammes SR. "Ovarian steroids: the good, the bad, and the signals that raise them." Cell cycle (Georgetown, Tex.). 2006; 5(11):1178-83. Epub 2006 Jun 01.
VanLandingham JW; Cutler SM; Virmani S; Hoffman SW; Covey DF; Krishnan K; Hammes SR; Jamnongjit M; Stein DG. "The enantiomer of progesterone acts as a molecular neuroprotectant after traumatic brain injury." Neuropharmacology. 2006; 51(6):1078-85. Epub 2006 Aug 22.
Rasar M; DeFranco DB; Hammes SR. "Paxillin regulates steroid-triggered meiotic resumption in oocytes by enhancing an all-or-none positive feedback kinase loop." The Journal of biological chemistry. 2006; 281(51):39455-64. Epub 2006 Oct 25.
Yang WH; Hammes SR. "Xenopus laevis CYP17 regulates androgen biosynthesis independent of the cofactor cytochrome b5." The Journal of biological chemistry. 2005; 280(11):10196-201. Epub 2005 Jan 07.
Haas D; White SN; Lutz LB; Rasar M; Hammes SR. "The modulator of nongenomic actions of the estrogen receptor (MNAR) regulates transcription-independent androgen receptor-mediated signaling: evidence that MNAR participates in G protein-regulated meiosis in Xenopus laevis oocytes." Molecular endocrinology (Baltimore, Md.). 2005; 19(8):2035-46. Epub 2005 Apr 14.
White SN; Jamnongjit M; Gill A; Lutz LB; Hammes SR. "Specific modulation of nongenomic androgen signaling in the ovary." Steroids. 2005; 70(5-7):352-60. Epub 2005 Mar 16.
Jamnongjit M; Hammes SR. "Oocyte maturation: the coming of age of a germ cell." Seminars in reproductive medicine. 2005; 23(3):234-41.
Jamnongjit M; Gill A; Hammes SR. "Epidermal growth factor receptor signaling is required for normal ovarian steroidogenesis and oocyte maturation." Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(45):16257-62. Epub 2005 Oct 31.
Gill A; Jamnongjit M; Hammes SR. "Androgens promote maturation and signaling in mouse oocytes independent of transcription: a release of inhibition model for mammalian oocyte meiosis." Molecular endocrinology (Baltimore, Md.). 2004; 18(1):97-104. Epub 2003 Oct 23.
Hammes SR. "Steroids and oocyte maturation--a new look at an old story." Molecular endocrinology (Baltimore, Md.). 2004; 18(4):769-75. Epub 2003 Nov 20.
Yang WH; Lutz LB; Hammes SR. "Xenopus laevis ovarian CYP17 is a highly potent enzyme expressed exclusively in oocytes. Evidence that oocytes play a critical role in Xenopus ovarian androgen production." The Journal of biological chemistry. 2003; 278(11):9552-9. Epub 2003 Jan 09.
Hammes SR. "The further redefining of steroid-mediated signaling." Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(5):2168-70. Epub 2003 Feb 26.
Lutz LB; Jamnongjit M; Yang WH; Jahani D; Gill A; Hammes SR. "Selective modulation of genomic and nongenomic androgen responses by androgen receptor ligands." Molecular endocrinology (Baltimore, Md.). 2003; 17(6):1106-16. Epub 2003 Mar 13.
Han S; Xie W; Hammes SR; DeJong J. "Expression of the germ cell-specific transcription factor ALF in Xenopus oocytes compensates for translational inactivation of the somatic factor TFIIA." The Journal of biological chemistry. 2003; 278(46):45586-93. Epub 2003 Aug 14.
Thøgersen IB; Hammes SR; Rubenstein DS; Pizzo SV; Valnickova Z; Enghild JJ. "New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor." Biochimica et biophysica acta. 2002; 1598(1-2):131-9.
Lutz LB; Cole LM; Gupta MK; Kwist KW; Auchus RJ; Hammes SR. "Evidence that androgens are the primary steroids produced by Xenopus laevis ovaries and may signal through the classical androgen receptor to promote oocyte maturation." Proceedings of the National Academy of Sciences of the United States of America. 2001; 98(24):13728-33. Epub 2001 Nov 13.
Lutz LB; Kim B; Jahani D; Hammes SR. "G protein beta gamma subunits inhibit nongenomic progesterone-induced signaling and maturation in Xenopus laevis oocytes. Evidence for a release of inhibition mechanism for cell cycle progression." The Journal of biological chemistry. 2000; 275(52):41512-20.
Hammes SR; Coughlin SR. "Protease-activated receptor-1 can mediate responses to SFLLRN in thrombin-desensitized cells: evidence for a novel mechanism for preventing or terminating signaling by PAR1's tethered ligand." Biochemistry. 1999; 38(8):2486-93.
Hammes SR; Shapiro MJ; Coughlin SR. "Shutoff and agonist-triggered internalization of protease-activated receptor 1 can be separated by mutation of putative phosphorylation sites in the cytoplasmic tail." Biochemistry. 1999; 38(29):9308-16.
Kahn ML; Hammes SR; Botka C; Coughlin SR. "Gene and locus structure and chromosomal localization of the protease-activated receptor gene family." The Journal of biological chemistry. 1998; 273(36):23290-6.
Trejo J; Hammes SR; Coughlin SR. "Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting." Proceedings of the National Academy of Sciences of the United States of America. 1998; 95(23):13698-702.
Hsu DK; Hammes SR; Kuwabara I; Greene WC; Liu FT. "Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3." The American journal of pathology. 1996; 148(5):1661-70.
Hammes SR; Greene WC. "Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function." Virology. 1993; 193(1):41-9.
Fung MR; Scearce RM; Hoffman JA; Peffer NJ; Hammes SR; Hosking JB; Schmandt R; Kuziel WA; Haynes BF; Mills GB. "A tyrosine kinase physically associates with the beta-subunit of the human IL-2 receptor." Journal of immunology (Baltimore, Md. : 1950). 1991; 147(4):1253-60.
Hammes SR; Dixon EP; Malim MH; Cullen BR; Greene WC. "Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor." Proceedings of the National Academy of Sciences of the United States of America. 1989; 86(23):9549-53.
Estes K; Monfalcone LL; Hammes SR; Holowka D; Baird B. "Membrane-bound IgE receptor complexes fused with rat basophilic leukemia cells mediate degranulation." The Journal of cell biology. 1987; 105(2):747-53.