Lab Members
Principal Investigator
The Goldman lab (Neurology’s Division of Cell & Gene Therapy) focuses on the role of glial pathology in aging and disease, and on neural as well as glial progenitor cell-based replacement strategies, with an emphasis on disease modeling and treatment.
Faculty
Development of new analytical methods to better understand in-vivo dynamics of glial replacement
Generation of human-glial chimeric mice to model and evaluate cell therapeutic interventions of CNS disease.
Surgical and histological techniques to support in vivo analysis of human glial progenitor cells in chimerized brain models for the goal of translating therapies in glial based neurodegenerative disorders.
Research Staff
Research Assistants
Evolving AAVs to target specific cell types for the delivery of specific cell types of the CNS. Elucidating disease mechanisms and identifying therapeutic intervention for neurodegenerative disorders.
