Research

  • Cell Cycle & Cancer

    Cell Cycle & Cancer

    Understanding the differences in cell division and its relationship to the development of cancer.

    Active Research Laboratories

    • Bambara Lab Human Genome Stability, DNA Damage Response, HIV Replication & Evolution
    • Land Lab Cooperation of Oncogenic Mutations in the Control of Malignancy
    • Maines Lab Heme Oxygenase, Biliverdin Reductase & Cell Signalling
    • Munger Lab Mechanisms of Pathogenic Metabolic Manipulation
  • Cell Signaling & Metabolic Regulation

    Cell Signaling & Metabolic Regulation

    Understanding complex system of communication that governs basic cellular activities and coordinates cell actions in order to effectively treat diseases.

    Active Research Laboratories

    • Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
    • Land Lab Cooperation of Oncogenic Mutations in the Control of Malignancy
    • Munger Lab Mechanisms of Pathogenic Metabolic Manipulation
  • Chromatin Structure, Gene Regulation & Repair

    Chromatin Structure, Gene Regulation & Repair

    Study of defined protein-DNA interactions, protein modification and mutations that influence chromatin structure and gene regulation.

    Active Research Laboratories

  • Genomics & Model Systems for Development

    Genomics & Model Systems for Development

    Determining DNA sequences of organisms and fine-scale genetic mapping efforts.

    Active Research Laboratories

    • Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
    • Grayhack Lab The Roles of the Genetic Code in Translation
    • Phizicky Lab tRNA Biogenesis, Function & Quality Control
    • Puzas Lab Molecular and Cellular Biology of the Skeletal System
  • Membrane Biology

    Membrane Biology

    The study of the biological and physiochemical characteristics of membranes.

    Active Research Laboratories

    • Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
    • Grossfield Lab Computer Modeling to Understand Structure and Thermodynamics of Biological Molecules
    • Mathews Lab Computational Biology and Bioinformatics
    • Waugh Lab Cell Deformability & Cell Adhesion
  • Molecular Biophysics

    Molecular Biophysics

    Combines concepts in physics, chemistry, engineering, mathematics and biology.

    Active Research Laboratories

  • Protein Structure & Function

    Protein Structure & Function

    Structure and function of proteins from primary to quaternary structures.

    Active Research Laboratories

  • RNA Structure & Processing

    RNA Structure & Processing

    Generation of a mature mRNA (for protein genes) or a functional tRNA or rRNA from the primary transcript.

    Active Research Laboratories

    • Butler Lab Regulation of mRNA Expression in the Nucleus of Eukaryotic Cells
    • Ermolenko Lab Mechanism of Protein Synthesis
    • Kielkopf Lab Pre-mRNA Splicing for Treatment of Human Disease
    • Maquat Lab Normal & Disease-Associated RNA Decay
    • Mathews Lab Computational Biology and Bioinformatics
    • Phizicky Lab tRNA Biogenesis, Function & Quality Control
    • Smith Lab Messenger RNA Expression & Processing
    • Wedekind Lab Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
    • Yu Lab Functions & Mechanisms of RNA Modifications