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Louis S. Constine, M.D.

Contact Information

Phone Numbers

Appointment: (585) 275-2171

Office: (585) 275-5622

Fax: (585) 275-1531

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Settings

Cancer, Radiation Oncology

Biography

I am a radiation oncologist with clinical and scientific expertise is in lymphomas, sarcomas, all pediatric malignancies, and the broad area of survivorship that includes the acute and chronic effects of chemotherapy and radiation therapy on normal tissues. I am fortunate to spend my life striving to help patients with cancer, optimizing their quality of life and curing them when possible.

My professional life is guided by my words: "For the survivor of cancer, the world is full and each day is a celebration; For the physician, each patient is an inspiration; For the person with cancer, each day is precious and must be faced with courage."

Conditions I Treat
- Lymphomas
- Sarcomas
- Pediatric hematology and oncology (including central nervous system cancer)
- Long term side effects of chemotherapy and radiation therapy

Professional Background

Louis S. Constine, MD, FASTRO, FACR is Professor of Radiation Oncology and Pediatrics and Vice Chair of the Department of Radiation Oncology. He is also the Director of the James P. Wilmot Cancer Institute Judy DiMarzo Survivorship Program. After graduating from Stanford University, and the Johns Hopkins University School of Medicine, he trained in pediatrics, pediatric oncology, and radiation oncology, and has board certification in these areas. He is a member of numerous societies including The American Society of Radiation Oncology, the Radiation Research Society, the American Society of Clinical Oncology, and the American Society of Hematology. He was awarded fellowships in the American Society of Radiation Oncology in 2008, and in the American College of Radiology in 2018.

Research

Dr. Constine is the Radiation Chair of the Lymphoma Committee in the Southwest Oncology Group. He is on the core committees for the Children’s Oncology Group Survivorship Guidelines, the International Survivorship Harmonization Guidelines, previously was on the American Society of Clinical Oncology Survivorship Advisory Group, and he leads the Pediatric Quantitative Analysis of Normal Tissue Effects in the Clinic ASTRO/AAPM initiative. He serves on the Children’s Oncology Group Late Effects Steering Committee, is senior advisor for the COG Hodgkin Lymphoma Committee, and is on the executive committee of the Radiation Oncology Committee (leading an effort to compile normal tissue dose constraints for protocols). He has been an investigator on several grants including an ROI evaluating long-term cardiac toxicities in Hodgkin lymphoma survivors. He is a member of the steering committee for the NCI-supported Childhood Cancer Survivorship Study. He was a member of a four-person United Nations task force collating the adverse effects of radiation on children; he discussed their 240-page document at the UN international headquarters (Vienna) in 5/2012 and again in 5/2013 and it was internationally distributed. Other international efforts included his core membership on an International Atomic Energy Agency initiative to develop pediatric radiation oncology in low-income countries. Additional activities include membership on task forces for the American Heart Association on cardiotoxicity, and the National Council on Radiation Protection Scientific Committee on “Second Primary Cancers and Cardiovascular Disease after Radiation Therapy.” Dr. Constine has authored (co-authored) edited more than 50 book chapters (including the 6th edition of Pediatric Radiation Oncology- British Medical Book Award), edited eight books and ~250 original and invited reports.

Credentials

Specialties

    Education

    1973
    MD | Johns Hopkins University School of Medicine (USA)

    Post-doctoral Training & Residency

    07/01/1978 - 06/30/1981
    Residency in Radiation Oncology at Stanford University Medical Center

    07/01/1976 - 06/30/1978
    Fellowship in Pediatric Hematology-Oncology at Seattle Children's Hospital

    07/01/1975 - 06/30/1976
    Residency in Pediatrics at Stanford University Medical Center

    07/01/1973 - 06/30/1975
    Residency in Pediatric Genetics at UCSF Medical Center Moffitt - Long Hospitals

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    Awards

    2018
    Fellow
    Sponsor: American College of Radiology (ACR)

    2018
    Educator of the Year
    Sponsor: Association of Residents in Radiation Oncology

    2017 - Present
    Albert Nelson Marquis Lifetime Achievement Award
    Sponsor: Marquis Who's Who

    2017
    Medical Book Awards: High Commendation (Oncology)
    Sponsor: British Medical Association

    2017
    America's Most Honored Professionals--Top 1%
    Sponsor: The American Registry

    2014
    Anna Meadows Distinguished Lecturer in Pediatric Oncology Survivorship
    Sponsor: University of Pennsylvania

    2013 - Present
    Philip Rubin Professor of Radiation Oncology and Pediatrics
    Sponsor: Department of Radiation Oncology
    Location: University of Rochester

    2012 - 2013
    Patient- and Family-Centered ICARE High Performance Award
    Sponsor: University of Rochester Medical Center
    Location: Rochester, NY

    2011
    Educator of the Year
    Sponsor: Association of Residents in Radiation Oncology

    2010
    Merit Award: PDQ Pediatric Treatment Editorial Board
    Sponsor: National Institutes of Health

    2008
    Fellow
    Location: American Society for Therapeutic Radiology and Oncology (ASTRO)

    2008
    Make a Difference Award
    Sponsor: Melissa's Living Legacy Teen Cancer Foundation
    Location: Rochester, NY

    2007 - Present
    America's Top Doctors for Cancer
    Sponsor: America's Best Doctors

    2007 - Present
    Best Doctor
    Sponsor: BestDoctors.com

    2005
    Philip Rubin-Mayer Mitchell Teaching Award
    Location: University of Rochester Department of Radiation Oncology

    2004
    Ring of Fire Award
    Location: Camp Good Days and Special Times

    2001
    Philip Rubin-Mayer Mitchell Teaching Award
    Location: University of Rochester Department of Radiation Oncology

    2001
    Jacob Gitelman Award
    Location: Cancer Action

    1997
    Philip Rubin-Mayer Mitchell Teaching Award
    Location: University of Rochester Department of Radiation Oncology

    1983 - 1986
    Junior Faculty Fellowship Award
    Location: American Cancer Society

    1983
    Teddy Award
    Location: Camp Good Days and Special Times

    1969
    Graduation with Distinction
    Location: Stanford University

    1969
    Beta Kappa

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    Publications

    Journal Articles

    1/2/2024
    Lo AC, Liu A, Liu Q, Yasui Y, Castellino SM, Kelly KM, Hererra AF, Friedberg JW, Friedman DL, Schwartz CL, Pei Q, Kessel S, Bergeron-Gravel S, Dama H, Roberts K, Constine LS, Hodgson DC. "Late Cardiac Toxic Effects Associated With Treatment Protocols for Hodgkin Lymphoma in Children." JAMA network open.. 2024 Jan 2; 7(1):e2351062. Epub 2024 Jan 02.

    2024
    Milano MT; Vargo JA; Yorke ED; Ronckers CM; Kremer LC; Chafe SMJ; van Santen HM; Marks LB; Bentzen SM; Constine LS; Vogelius IR. "Primary hypothyroidism in childhood cancer survivors treated with radiotherapy: A PENTEC comprehensive review". Int J Radiat Oncol Biol Phys. 2024; in press.

    2024
    Constine LS; Olch AJ; Jackson A; Hua C-H; Ronckers C; Milano MT; Marcus KJ; Yorke E; Hodgson D; Howell R; Hudson M; Williams J; Marples B; Kremer L; Marks LB; Bentzen SM. "Pediatric Normal Tissue Effects in the Clinic (PENTEC): an international collaboration to assess normal tissue radiation dose-volume-response relationships for children with cancer". Int J Radiat Oncol Biol Phys. 2024; in press.

    Books & Chapters

    2021
    Chapter Title: Late Effects After Radiation
    Book Title: Clinical Radiation Oncology
    Author List: Milano MT; Marks LB; Constine LS
    Edited By: Tepper JE; Foote RL; Michalski JM
    Published By: Elsevier 2021 in Philadelphia

    2021
    Chapter Title: Pediatric Hodgkin Lymphoma
    Book Title: Clinical Radiation Oncology
    Author List: Roberts KB; Hoppe BS, Kelly KM; Constine LS
    Edited By: Tepper JE; Foote RL; Michalski JM
    Published By: Elsevier 2021 in Philadelphia

    2018
    Chapter Title: Hypopituitarism
    Book Title: Adult CNS Radiation Oncology
    Author List: Hardy S; Milano MT; Shafiq I; Vates GE; Constine LS
    Published By: Springer 2018 in New York, NY

    VIEW ALL PUBLICATIONS

    Videos

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    SECOND OPINION | Late Effects of Cancer Treatment | APT | Full Episode

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    SECOND OPINION | Late Effects of Cancer Treatments | APT | Webisode

    Reviews

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