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At Wilmot Cancer Institute, you will find the region’s most advanced treatments for brain and spine cancer. Each patient’s case is discussed in a multidisciplinary tumor board, where brain and spine surgeons, neuro-oncologists, neurologists, radiation oncologists and neuropathologists all meet together to outline a personalized plan of care.

Options for the treatment of brain and spine tumors can include combinations of:


In addition to its use for diagnosing brain and spine tumors, surgery can be used to remove as much of the tumor as possible. Procedures can include:

  • Craniotomy, which is an open surgery providing direct access to the brain so a tumor can be removed.
  • Transsphenoidal tumor resection, which is a minimally invasive surgery often used to remove tumors of the pituitary gland.


Radiation therapy uses photon energy generated by a linear accelerator to treat brain or spine tumors. Advanced techniques available for treating brain and spine tumors at Wilmot Cancer Institute include:

  • Stereotactic radiosurgery (SRS), which delivers radiation in one dose using a 3-dimensional coordinate system to more accurately target the tumor and to protect healthy tissue.
  • 3D conformal radiation therapy (3D-CRT), which uses sophisticated imaging and positioning systems to “conform” the radiation beam to the size and shape of a tumor for exceptional precision. Radiation beams are then precisely shaped and directed at the tumor from various angles. This process directs more radiation at the tumor while minimizing exposure of normal cells.
  • Intensity modulated radiation therapy (IMRT), which is an advanced form of 3D conformal radiation therapy that the intensity of individual radiation beams to vary. IMRT delivers more intense radiation to cancer cells while providing greater protection to normal cells.


Chemotherapy is often used along with surgery and/or radiation to kill tumor cells or prevent them from growing. Because many anticancer drugs traditionally delivered though the bloodstream cannot reach the brain or spinal fluid, some chemotherapy for brain and spine tumors is delivered directly into the cerebrospinal fluid, brain or spinal canal. A dissolvable wafer containing an anticancer drug can also be placed on or near parts of a tumor that cannot be removed during surgery.

Targeted therapies

These therapies are designed to attack specific cancer cells either by interfering with the mechanisms that cause them to grow and spread or by engaging the immune system to kill the cancer cells.

Tumor-treating field therapy

This innovative new therapy for glioblastoma uses alternating electric fields to interfere with cell division and keep the cancer from growing.

Side Effects

Many cancer treatments cause side effects such as hair loss or fatigue, but not everyone will have the same side effects. 

The American Cancer Society also offers a free online class to help patients manage the side effects of their illness.