What to Expect Following Apheresis Following treatment, you can eat and drink as you usually do. Do not drink alcohol for the remainder of the day. Do not smoke for at least one hour after treatment to prevent dizziness. You may feel tired for the remainder of the day or for one to two days after a total plasma exchange due to decreased plasma protein levels. If necessary, rest before resuming normal activities. The apheresis medical director will discuss treatment results and the possibility of additional treatments, if necessary. Remember to ask your nurse what type of apheresis you had so that you can inform other healthcare professionals, if necessary. If a catheter was used for your treatment, it will be flushed and new end caps will be applied. Some activity restrictions may be ordered to protect the catheter. If IVs were used for treatment, a pressure bandage will be applied at the needle sites. Please keep these bandages on and dry for at least four hours. You may remove the dressing if there is no bleeding. Avoid lifting heavy objects for at least 24 hours. If the needle sites begin to bleed, raise your arm above your head and apply light pressure to the bandage until the bleeding stops. If the bleeding does not stop after several minutes, call the Apheresis Program at (585) 275-7447 during regular business hours. Call your primary care physician or go to the nearest emergency department if you feel light-headed or persistently nauseated or experience other discomfort. You can always call the Apheresis Program at (585) 275-7447. After hours, call (585) 275-2222 and ask the operator to page the Apheresis physician on call. Call your primary care physician immediately if you notice redness, drainage, or discomfort at the insertion site; fever; or other signs of infection.