CHAN17022 / EA3132 / Ronald MaggioreResearch Question:
Do the changes in a gene called TP53 influence the response to radiation therapy alone
or radiation therapy in combination with cisplatin chemotherapy?
Basic Study Information
Purpose:Location: Cancer Center
This phase II trial studies how well radiation therapy with or without cisplatin works
in treating patients with stage III-IVA squamous cell carcinoma of the head and neck
who have undergone surgery. Radiation therapy uses high energy x-rays to kill tumor
cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin, work in different
ways to stop the growth of tumor cells, either by killing the cells, by stopping them
from dividing, or by stopping them from spreading. It is not yet known if radiation
therapy is more effective with or without cisplatin in treating patients with squamous
cell carcinoma of the head and neck.
Study Web URL: https://clinicaltrials.gov/ct2/show/NCT02734537?term=ea3132&rank=1
Study Reference #: CHAN17022
Lead Researcher (Principal Investigator)
Study Contact InformationStudy Coordinator: Nichole Ransom
Phone: +1 585-276-8747
Additional Study Details
Learn More About These Conditions
More information about Carcinoma, Squamous Cell
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