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Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Research Question:
Does the drug larotrectinib treat patients with solid tumors, non-Hodgkin lymphoma or histiocytic disorders?

Basic Study Information

Purpose:
This phase II Pediatric MATCH trial studies how well larotrectinib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with NTRK fusions that have spread to other places in the body and have come back or do not respond to treatment. Larotrectinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Location: University of Rochester

Lead Researcher (Principal Investigator)

Lead Researcher: Angela Girvin

Study Contact Information

Phone: (585) 275-5830

Additional Study Details

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Wilmot Clinical Trials