Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation
Therapy in Treating Patients With Newly Diagnosed Ependymoma
How well does maintenance chemotherapy work in patients with newly diagnosed ependyoma?
Basic Study Information
Purpose:Location: University of Rochester
This partially randomized phase III trial is studying maintenance chemotherapy to
well it works compared to observation following induction chemotherapy and radiation
in treating young patients with newly diagnosed ependymoma. Drugs used in chemotherapy,
as vincristine sulfate, carboplatin, cyclophosphamide, etoposide, and cisplatin, work
different ways to stop the growth of tumor cells, either by killing the cells, by
them from dividing, or by stopping them from spreading. Giving more than one drug
(combination chemotherapy) may kill more tumor cells. Radiation therapy uses high-energy
x-rays to kill tumor cells. Specialized radiation therapy that delivers a high dose
radiation directly to the tumor may kill more tumor cells and cause less damage to
tissue. Giving chemotherapy with radiation therapy may kill more tumor cells and allow
doctors to save the part of the body where the cancer started.
Lead Researcher (Principal Investigator)
Lead Researcher: Angela Girvin
Study Contact InformationPhone: (585) 275-5830
Additional Study Details
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