CGYC16057 / NRG-GY006 / Richard Moore
Basic Study Information
Purpose:Location: University of Rochester
This randomized phase III trial studies radiation therapy and cisplatin with triapine
to see how well they work compared to the standard radiation therapy and cisplatin
alone in treating patients with newly diagnosed stage IB2, II, or IIIB-IVA cervical
cancer or stage II-IVA vaginal cancer. Radiation therapy uses high energy protons
to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin,
work in different ways to stop the growth of tumor cells, either by killing the cells,
by stopping them from dividing, or by stopping them from spreading. Triapine may stop
the growth of tumor cells by blocking some of the enzymes needed for cell growth.
It is not yet known whether radiation therapy and cisplatin are more effective with
triapine in treating cervical or vaginal cancer.
Lead Researcher (Principal Investigator)
Study Contact InformationStudy Coordinator: Chelsea Marsh
Phone: +1 585-273-3970
Additional Study Details
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