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CogT BEEM Study: Addressing Emotional Regulation and Memory with Non-Invasive Brain Stimulation

Research Question:
In older adults with mild memory difficulties, what is the effect of non-invasive brain stimulation on symptoms like irregular mood and memory?

Basic Study Information

Purpose:
If you have noticed changes in memory or thinking abilities as well as changes in mood, you may be eligible for this study. To participate, you must be between 60-89 years old, and identify someone close to you to briefly participate as your study partner. This study involves three assessments evaluating your cognition and mood, three MRI brain scans, and one blood draw. You would be randomly assigned to receive either 14 guided, non-invasive, low-risk brain stimulation sessions (20 minutes of stimulation per session) – or 14 sham/placebo sessions (30 to 40 seconds of stimulation per session) over a 4-week period. All sessions will take place with a study team member and can occur in the comfort of your home or a location convenient for you. Up to $170 for participating.

Study Reference #: 00003664

Lead Researcher (Principal Investigator)

Lead Researcher: Feng Lin

Study Contact Information

Study Coordinator: Sabrina Goyal
Phone: (585) 276-5802
Email: Sabrina_Goyal@urmc.rochester.edu

Additional Study Details

Study Details:
Neuropsychiatric symptoms in patients with mild memory difficulties, especially those worsening over time, are associated with more rapid cognitive and functional decline and a greater risk of Alzheimer's disease. Effectively managing multiple symptoms requires a solid understanding of the shared brain mechanism across neuropsychiatric symptoms.

Reimbursement:  Yes

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