CGYM19142 / NRG-GY019 / Richard MooreResearch Question:
How well does letrozole - with or without paclitaxel and carboplatin - work in treating
patients with stage II-IV low-grade serous carcinoma of the ovary or peritoneum?
Basic Study Information
Purpose:Location: University of Rochester Medical Center
This phase III trial studies how well letrozole with or without paclitaxel and carboplatin
works in treating patients with stage II-IV low-grade serous carcinoma of the ovary,
fallopian tube, or peritoneum. Letrozole is an enzyme inhibitor that lowers the amount
of estrogen made by the body which in turn may stop the growth of tumor cells that
need estrogen to grow. Drugs used in chemotherapy, such as paclitaxel and carboplatin,
work in different ways to stop the growth of tumor cells, either by killing the cells,
by stopping them from dividing, or by stopping them from spreading. It is not yet
known whether giving letrozole alone or in combination with paclitaxel and carboplatin
works better in treating patients with low-grade serous carcinoma of the ovary, fallopian
tube, or peritoneum compared to paclitaxel and carboplatin without letrozole.
Study Reference #: CGYM19142
Lead Researcher (Principal Investigator)
Study Contact InformationStudy Coordinator: Jessica Mackowiak
Additional Study Details
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