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The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-acute lymphoblastic leukemia (ALL)

Research Question:
Is not providing total body irradiation in B cell ALL patients effective before the patient receives a stem cell transplant?

Basic Study Information

Purpose:
This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by the lack of residual disease (NGS-MRD before receiving a hematopoietic cell transplant (HCT). Patients diagnosed with B-ALL who are candidates for a transplant will be screened on a test of bone marrow done before the transplant.

Location: University of Rochester Medical Center
Study Reference #: PLEU19018

Lead Researcher (Principal Investigator)

Lead Researcher:  Jeffrey Andolina

Study Contact Information

Study Coordinator: Haley Misch
Phone: (585) 275-9485
Email: Haley_Misch@URMC.Rochester.edu

Additional Study Details

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