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Nicotine Vapor Sensory Study

Research Question:
Are flavors related to the phenomenon of "indirect" toxicity? That is, regardless of whether flavorings show evidence of toxicity in a biological sense, do they increase harm by other means, such as increasing appeal, decreasing risk perceptions, or masking harshness or irritation that might lead users to discontinue use?

Basic Study Information

Purpose:
The study focuses on developing reliable and valid measures of sensory experiences unique to e-cigarette use, commonly described as "throat hit" from the carrier liquid, nicotine form/concentration, and device power. The degree of "throat hit" can influence how vapers use these devices and thus affect their exposure to components in e-cigarette aerosols. During 3 phases of the study, adult participants (all current vapers of nicotine products) will take a fixed number of puffs from an e-cigarette that varies in carrier concentration, nicotine concentration, nicotine form (free base or salt), and differing device power levels. Participants will complete a range of sensory, simulated purchase decision making, and response measures. To be included in this study, subjects must meet the following criteria: 1) Aged 21-55, 2) Current daily vapers of products containing nicotine, 3) No concurrent use of other tobacco products, 4) General good health, 5) No allergies (specifically known active untreated seasonal allergies that would interfere with smell or taste procedures), 6) No self-reported taste or smell deficits.

Location: Virtual
Study Reference #: 0004548

Lead Researcher (Principal Investigator)

Lead Researcher:  Deborah Ossip

Study Contact Information

Study Coordinator: URMC CRoFT Study Team
Phone: (585) 330-7034
Email: croft_study@urmc.rochester.edu

Additional Study Details

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