April 26, 2017 ( Wednesday )


Research Meetings
12:30pm - 1:30pm
Center for Oral Biology Bagel Talks 2017-2018

Dorota T. Kopycka-Kedzierawski, D.D.S., M.P.H.

Associate Professor, Department of Dentistry

"Management of Dentin Hypersensitivity: results from a cohort study conducted by National Dental PBRN Practitioners"

Location:  COB Conference room, G9654, KMRB

Posted by:  Nicole Beaumont, Center for Oral Biology, 17-Apr-17 2:16pm ET


Other Events & Dates
2:00pm - 3:00pm
Department of Biochemistry & Biophysics Seminar Series

Graeme L. Conn, Ph.D., Associate Professor, Department of Biochemistry, Emory University School of Medicine, Atlanta, GA

"Ribosomal RNA Modification and Bacterial Antibiotic Resistance"

Host: Dr. Eric Phizicky (Co-sponsored by the RNA Structure and Function Cluster)

2:00 - 3:00 pm

K307 (3-6408)

Location:  K307 (3-6408)

Posted by:  Stephanie Scoville, Biochem & Biophys, 22-Dec-16 12:56pm ET


Research Meetings
4:00pm - 5:00pm
The Aab CVRI Seminar Series

SPEAKER: Magdalena Chrzanowska-Wodnicka, PhD, FAHA Investigator Blood Research Institute BloodCenter of Wisconsin Adjunct Associate Professor Department of Pharmacology & Toxicology Medical College of Wisconsin

TITLE OF TALK: "Novel mechanisms of endothelial homeostasis"

Small GTPase Rap1 is well-known for promoting cell adhesion in vitro. Through our studies with endothelial specific Rap1-knockout mice we have discovered that Rap1, by promoting signaling from Vascular Endothelial Growth Factor Receptor (VEGFR) 2, regulates angiogenesis and endothelial barrier in vivo. Furthermore, our recent research revealed a novel, important function of Rap1 in sensing vascular shear stress and nitric oxide (NO) production. Physiological significance of this finding is underscored by hypertension and endothelial dysfunction in Rap1-knockout mice. Our studies suggest novel mechanisms through which Rap1 plays a key role in regulation of endothelial homeostasis.

Location:  CVRI Conf. Room # G.11211/G.11213 MRBX/Delmonte Bldg - (Ground floor)

Posted by:  Jacqueline Velazquez, Cardiovascular Research Institute, 25-Apr-17 11:51am ET


Research Meetings
7:00pm
Precision MedicineóNotre Dameís Bold Initiative to Lead the 21st Century Revolution in Personalized Healthcare

Paul W. Bohn, Ph.D.
University of Notre Dame Arthur J. Schmitt Professor of Chemical and Biomolecular Engineering Professor of Chemistry and Biochemistry Director, Advanced Diagnostics & Therapeutics Initiative

Contemporary therapeutics rests principally on epidemiology, large-scale trials of therapeutic interventions, and average responses. Precision medicine moves beyond this paradigm by delivering the right treatment to the right person at the right time. It brings together clinicians and basic researchers to identify - and learn how to use - individual/personal "molecular keys" that combine an individual's genomic makeup with time/space localized information about organ/tissue-specific protein expression (proteomics) and function (metabolomics). This information, obtained ideally from small samples - even a single cell – could form the basis for earlier, potentially pre-symptomatic diagnoses and individually-tailored therapies to enhance the effectiveness of treatment. This talk will describe Notre Dame's holistic approach to precision medicine, going well beyond genetic information to target a broad panel of molecular markers, including proteins and metabolites, and the development of new and potentially revolutionary new biomedical technologies, like electrokinetic micro-RNA chips, clinical instruments printed on paper, and ultra high efficiency and sensitivity separations to analyze single somatic cells, i.e. chemical cytometry.

Click here for a video on Dr. Bohn's work. For additional information please visit http://rochester.undclub.org

Location:  Adolph Auditorium University of Rochester Medical Center

Posted by:  Susanne Pallo, Clinical & Translational Sciences Inst, 3-Mar-17 1:44pm ET

 
 
https://www.urmc.rochester.edu/calendar/index.html