Precision MedicineóNotre Dameís Bold Initiative to Lead the 21st Century Revolution in Personalized Healthcare
Paul W. Bohn, Ph.D.
University of Notre Dame Arthur J. Schmitt Professor of Chemical and Biomolecular Engineering Professor of Chemistry and Biochemistry Director, Advanced Diagnostics & Therapeutics Initiative
Contemporary therapeutics rests principally on epidemiology, large-scale trials of therapeutic interventions, and average responses. Precision medicine moves beyond this paradigm by delivering the right treatment to the right person at the right time. It brings together clinicians and basic researchers to identify - and learn how to use - individual/personal "molecular keys" that combine an individual's genomic makeup with time/space localized information about organ/tissue-specific protein expression (proteomics) and function (metabolomics). This information, obtained ideally from small samples - even a single cell could form the basis for earlier, potentially pre-symptomatic diagnoses and individually-tailored therapies to enhance the effectiveness of treatment. This talk will describe Notre Dame's holistic approach to precision medicine, going well beyond genetic information to target a broad panel of molecular markers, including proteins and metabolites, and the development of new and potentially revolutionary new biomedical technologies, like electrokinetic micro-RNA chips, clinical instruments printed on paper, and ultra high efficiency and sensitivity separations to analyze single somatic cells, i.e. chemical cytometry.
Click here for a video on Dr. Bohn's work. For additional information please visit http://rochester.undclub.org
|Location: ||Adolph Auditorium University of Rochester Medical Center|
Posted by: Susanne Pallo, Clinical & Translational Sciences Inst, 3-Mar-17 1:44pm ET