Stages of Childhood Hodgkins Disease Stage I Cancer is found in only 1 lymph node area or in only 1 area or organ outside of the lymph nodes. Stage II Either of the following means the disease is stage II: Cancer is found in 2 or more lymph node areas on the same side of the diaphragm (the thin muscle under the lungs that helps with breathing). Cancer is found in only 1 area or organ outside of the lymph nodes and in the lymph nodes around it. Other lymph node areas on the same side of the diaphragm may also have cancer. Stage III Cancer is found in lymph node areas on both sides of the diaphragm. The cancer may also have spread to an area or organ near the lymph node areas and/or to the spleen. Stage IV Either of the following means the disease is stage IV: Cancer has spread in more than 1 spot to an organ or organs outside of the lymph system. Cancer cells may or may not be found in the lymph nodes near these organs. Cancer has spread to only 1 organ outside of the lymph system, but lymph nodes far away from that organ are involved. Recurrent The cancer has come back after it has been treated. It may come back in the area where it first started or in another part of the body.