Stages of Retinoblastoma Although there are several staging systems for retinoblastoma, for treatment purposes, retinoblastoma is often staged according to the location of the cancer. Retinoblastoma is typically described in the following terms: Intraocular Retinoblastoma Cancer is found in one or both eyes, but does not extend beyond the eye into the tissues around the eye or to other parts of the body. Extraocular Retinoblastoma Cancer has extended beyond the eye. It may be confined to the tissues around the eye, or it may have spread to other parts of the body. Recurrent The cancer has come back after it has been treated. It may come back in the area where it first started or in another part of the body.