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Research

Research performed by the Division of Pediatric Pulmonology focuses on improving our understanding and treatment of the pulmonary diseases that occur in children. Most of our research is funded by agencies such as the National Institutes of Health and the Cystic Fibrosis Foundation. We conduct clinical trials to develop new therapies and cures for children with respiratory illness.

Current clinical trials include:

  • Early Pseudomonas Infection and Control (EPIC) Study: Study to determine the best way to eliminate and control early Pseudomonas infection in children with cystic fibrosis (CF).
  • Gene Modifier Study: Study to identify modifier genes that affect the severity of CF lung disease.
  • Tobramycin Powder for Inhalation Study: Tests the effectiveness of a new formulation of inhaled tobramycin in CF patients that is much easier to administer than current forms.
  • DHA Supplementation in CF Infants: Study to determine if supplementing the formula of babies with CF will improve their growth and development.
  • The Lung Flute Study: Tests the effectiveness of a new device to help cough out mucus in CF patients.
  • Ventolin HFA Study: Tests the effectiveness of a new formulation of albuterol, a bronchodilator, in infants and toddlers with wheezing or asthma.

In addition to these clinical trials, we also conduct research to help us better understand how pulmonary diseases develop and how to best evaluate children with pulmonary diseases. These research activities include:

  • Differential Gene Expression in P. aeruginosa: Strives to identify the important genes made by P. aeruginosa, a common pathogen in CF patients.
  • Epidemiologic Study of Cystic Fibrosis (ESCF): A longitudinal observational study of CF in North America. Data is used to identify practice patterns, clinical outcomes, and the relationship between practice patterns and outcomes.
  • Synagis Observational Study: A longitudinal observational study of pulmonary complications in premature infants who are receiving Synagis.
  • Preschool PFT Study: Compares three methods of pulmonary function testing in preschool-aged children with CF.

For further information about research in the Division, or to participate in our research projects, please call Amy Rovitelli, our Research Coordinator, at (585) 275-2464.

Find more information at the Strong Children's Research Center.