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i2b2 is an open-source software system that allows users to query clinical data to estimate the size of clinical cohorts available for specific studies, allows for the creation of “data marts” to support the requirements of particular studies, and supports an efficient mechanism to transfer clinical data directly to REDCap. Data is available in a de-identified manner for study planning, but HIPAA identifiers can be made available in the context of an IRB-approved study.

Training is strongly encouraged before a new user may access the system. Warning: use of the system without training may lead to misinterpretation of results. Register for training.

The software was originally developed with NIH funding by the Informatics for Integrating Biology and the Bedside (i2b2) Program based at Partners HealthCare System in Boston, established in 2004.

Access i2b2 here.