Multi-Drug Resistant Gram Negative Bacilli (MUGSI) Surveillance
To conduct population based surveillance for Multi-Drug Resistant Gram Negative Bacilli (MuGSI) of residents of Monroe County, NY in order to estimate the burden of disease and observe any increase in incidence.
Goals and Objectives
To evaluate the population-based incidence of carbapenem-nonsusceptibility among common strains of Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter species and describe how the incidence changes over time
To better characterize carbapenem-nonsusceptible strains in sites submitting data in order to inform prevention efforts
To describe known resistance mechanisms among a subset of carbapenem-nonsusceptible Enterobacteriaceae
Working with laboratories in Monroe County, the surveillance team will identify carbapenem resistant organisms, as well as those resistant to third generation cephalosporins. Case-patients infections will be characterized as hospital-onset, healthcare-associated community onset, or community-associated. Selected isolates will be sent to the Centers for Disease Control and Prevention (CDC) for further study.
Demographic data, as well as data about the nature of the identified bacterial culture will be collected on a case report form and entered into a database for submission to the CDC.
Our surveillance will contribute to the surveillance of over 12 million people performed by epidemiologists in Colorado, Georgia, Maryland, Minnesota Oregon, and New Mexico.
In 2015, the Centers for Disease Control and Prevention initiated a pilot study to capture the incidence of Pseudomonas aeruginosa. The New York-Rochester EIP participated in this pilot and surveillance will continue for this organism in 2016.
Guh, A: Bulens., SN; Mu, Y; Jacob, JT; Reno, J; Scott, J; Wilson, LE, Sc,M; Vaeth, E; Lynfield, R; Shaw, KM; Snippes, PM; Vagnone, MT(ASCP); Bamberg, WM; Janelle, SJ; Dumyati, G; Concannon, C; Beldavs, Z; Cunningham, M; Cassidy, M; Phipps, EC; Kenslow, N; Travis, T; Lonsway, D; Rasheed, JK; Limbago, BM; Kallen, AJ. Epidemiology of Carbapenem-Resistant Enterobacteriaceae in 7 US Communities, 2012-2013. Journal of the American Medical Association. 5 October 2015. Article Link
Magill, SS; Dumyati, G; Ray, SM; Fridkin, SK. Evaluating Epidemiology and Improving Surveillance of Infections Associated with Health Care, United States. Emerging infectious diseases. 2015 Sep; 21(9):1537-42. Article Link
Chea N, Bulens SN, Kongphet-Tran T, Lynfield R, Shaw KM, Vagnone PS, Kainer MA, Muleta DB, Wilson L, Vaeth E, Dumyati G, Concannon C, Phipps EC, Culbreath K, Janelle SJ, Bamberg WM, Guh AY, Limbago B, Kallen AJ. Improved Phenotype-Based Definition for Identifying Carbapenemase Producers among Carbapenem-Resistant
Enterobacteriaceae. Emerging infectious diseases. 2015 Sep; 21(9):1611-6. Article Link