NIH/NCI/National Clinical Trials Network (NCTN)

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This funding opportunity announcement (FOA) solicits applications from institutions/organizations for the NCI National Clinical Trials Network (NCTN). The goal of the NCTN is to develop and conduct state-of-the-art cancer treatment and advanced imaging clinical trials, especially large, definitive, multi-institutional trials evaluating new cancer therapies and related clinical approaches for both adult and pediatric patients. The NCTN consists of six components, each with its own FOA, which are listed below.

The NCTN Network Group Operations Centers will provide scientific leadership for developing and implementing multi-disciplinary, multi-institutional trials in a range of cancer types and special populations with specific scientific strategy and goals.

The NCTN Network Group Statistics and Data Management Centers will provide statistical expertise for effective scientific design and conduct of clinical trials, as well as data management for NCTN trials led by the associated Network Group Operations Centers.

The NCTN Network Group Integrated Translational Science Centers will provide support for leadership and expertise to facilitate incorporating translational science into Network Group clinical trials.

The NCTN Network Lead Academic Participating Sites will provide scientific leadership in development and conduct of clinical trials in association with one or more adult Network Groups, as well as substantial accrual to clinical trials conducted across the entire NCTN.

The NCTN Network Radiotherapy and Imaging Services Centers will provide scientific and technical expertise for incorporation of appropriate, integrated quality assurance and image data management for these modalities in applicable clinical trials conducted by the NCTN Program.

The NCTN Canadian Collaborating Clinical Trials Network will be a full partner with the U.S. Network in the conduct of large-scale, multi-site clinical trials and help provide regulatory expertise/oversight for the conduct of NCTN trials in Canada. The competition for an award under this FOA is limited to eligible Canadian institutions.

The University may submit only one (1) application in response to this FOA. An organization applying for the Network Group Statistics and Data Management Center award under RFA-CA-12-011 or for the Network Radiotherapy and Imaging Core Services Center award under RFA-CA-12-014 cannot apply for a Network Group Operations Center award under this FOA.

Interested faculty must submit an abstract, CV, and budget to Dean Puzas ( by August 27, 2012. Please use the words “NCTN” in the subject line. The Deans will choose a candidate by September 7, 2012.

The Letter of Intent is due December 15, 2012. The full proposal is due January 15, 2013. It is important to remember that ORPA must receive electronic proposals five (5) business days prior to the sponsor’s deadline along with a completed and signed University sign-off form.


NIH Funding Acknowledgement ** Important ** All publications resulting from the utilization of CTSI resources are required to credit the CTSI grant by including the NIH FUNDING ACKNOWLEDGEMENT and must comply with the NIH Public Access Policy.