Doris Duke Charitable Foundation
Doris Duke Clinical Scientist Development Award

This grant program is designed to provide support to physician scientists (M.D. or M.D./Ph.D.) during their transition from training to independent research career. The goal of the program is to encourage physicians to pursue careers in clinical research. The Duke Foundation’s understanding of clinical research is described below under Research Interests.
Amount: $150,000 direct and $12,000 indirect per year for three years, total of $486,000.
Number of Nominations: The dean of the medical school can nominate two candidates.
Number of Awards: Approximately 12 per year. 
Foundation Application Deadline: Tentatively, November 16, 2011 for nominations and December 21, 2011 for applications.
Internal Review/Selection Deadline: October 21, 2011.
Faculty with questions about deadlines/eligibility criteria should contact Dr. Paul A. Spengler, Director of UR Foundation Relations, at 276-3955 or at

Internal/External Deadlines

  • The dean of the medical school can nominate two candidates.
  • Faculty wishing to be considered should email their expression of interest by October 21, 2011 to Catherine Muzytchuk, with the words DUKE CLINICAL SCIENTIST DEVELOPMENT AWARD in the subject line and must attached (1) cover form, (2) a chair’s nomination form, (3) NIH formatted biosketch in PDF format, (4) a brief, three-page abstract describing the significance of the proposed research, and (5) the Doris Duke Reference Sheet (this form requests information the dean’s office will need to nominate you, if you are selected). The required forms are attached.
  • The dean’s office will notify nominated faculty prior to November 16th and will notify the Doris Duke Charitable Foundation by that date.
  • Once the candidates have been notified of their nomination by the dean’s office, they should contact Dr. Paul A. Spengler, Director of UR Foundation Relations at 276-3955 or to review the program guidelines and for assistance with the application.

Eligibility Requirements

  • Be a physician scientist conducting clinical research in any disease area,
  • Have received an M.D. or foreign equivalent from an accredited institution,
  • Be working in a U.S. degree-granting institution, but do not have to be a U.S. citizen,
  • Have a full-time faculty level position not higher than the Assistant Professor level; and
  • Have been appointed to their first full-time faculty level position between January 1, 2007 and January 1, 2012. (All full-time post-fellowship Instructor level positions will be considered full-time faculty level appointments. Adjuncts/acting faculty are not eligible.)
  • Be guaranteed 75% protected research time.
  • The Doris Duke Charitable Foundation strongly encourages the nomination of women and underrepresented minorities (i.e., African Americans, Hispanics, native Alaskans and Hawaiians).

Research Interests

  • Propose a clinical research project, as defined by the Doris Duke Charitable Foundation, in any disease area:
      • Clinical research involves the scientific investigation of the etiology, prevention, diagnosis, or treatment of human disease using human subjects, human populations or materials of human origin. Included in the definition are studies that utilize tissues or pathogens only if they can be linked to a patient. Research projects involving animals or animal tissues are not eligible.
      • It is expected that research protocols of applicants will require IRB approval. IRB approval need not be in place at the time of application, but must be in place before the award will be finalized. If your project does not require IRB approval, please contact Foundation Relations (Dr. Paul Spengler) who will contact the Doris Duke Foundation regarding the eligibility of the project.
  • Basic discovery research. Investigations to increase basic knowledge and understanding, not aimed at uncovering the cause of human disease.
  • Etiology/Mechanism of Disease. Studies of the origins and causes of disease.
  • Prevention. Studies of nutrition, behavioral change, chemoprevention, vaccines.
  • Detection/Diagnosis/Prognosis. Biomarker discovery, technology development, predictive models.
  • Treatment. Discovery and development of new therapies; phase 1-3 clinical trials of therapeutics or interventions.
  • Outcomes Research. Health service research, effectiveness research, Phase 4 trials, educational research, cost analysis, bioethics.
  • Scientific Model Systems. Resource development only; development of cell culture models, computer models, etc.

Protected Time Requirement

  • The institution must agree to provide the grantee with a minimum of 75 percent of full-time professional effort to conduct research.

Mentoring Requirement

  • Mentoring is a requirement.

Limitation on Other Awards

  • An award will not be made if, prior to the commencement of the Duke CSDA, the applicant has been or becomes the PI or co-PI on an NIH, peer reviewd, R01, P01, P50 or U01 grant.
  • Applicants may hold an NIH K series award or other career development award at the same time as the Duke CSDA grant. However, the applicant must propose distinct and different research aims in their CSDA application and there should be no scientific overlap.

Application Materials:
Faculty Expression of Interest Cover Page
Chair's Nomination Form
Format for Internal Research Abstract
Doris Duke Nomination Reference Sheet


NIH Funding Acknowledgement ** Important ** All publications resulting from the utilization of CTSI resources are required to credit the CTSI grant by including the NIH FUNDING ACKNOWLEDGEMENT and must comply with the NIH Public Access Policy.