Infrastructure in Patient-Centered Outcomes Research (PCOR)

The Agency for Healthcare Research and Quality (AHRQ) has recently announced an initiative providing up to $1 million in funds, for up to 5 years, to develop and to provide Infrastructure in Patient-Centered Outcomes Research (PCOR).  Funded by the Affordable Care Act (ACA), this initiative seeks to develop professional capacity to conduct PCOR consistent with the methodologic framework established and funded by the Patient-Centered Outcomes Research Institute (PCORI).

This Funding Opportunity Announcement (FOA) seeks “Resource-Related Research Projects (R24) grant applications from organizations that propose to improve health outcomes by developing and disseminating evidence-based information to patients, clinicians, policy makers, and health care administrators, responding to their expressed needs about which clinical and health system design interventions are most effective for which patients under specific circumstances.”

“The overall goals of this FOA are to: 1) provide faculty/research staff methodological expertise in [Comparative Effectiveness Research] through the conduct of research projects and other professional development activities; and 2) strengthen the underlying institutional infrastructure needed to support PCOR.”

Each institution is limited to one awarded R24 under this FOA, with a requirement to establish 1) an Infrastructure Development Core; and 2) “Three to five multi-year individual investigator research projects related to the thematic research focus of the application’s proposed program.”  To qualify for this funding, we seek to establish a “thematic research focus…that unites proposed infrastructure activities and research projects.” 

To this end, we are soliciting 1- or 2-page abstracts that include your suggestion for (A) a "theme" and/or (B) a description of the project(s). Please highlight your relevant experience, preliminary data (for a project) and important collaborations with community partners and stakeholders. Consistent with the funding announcement, the project(s) could include new data gathering, analysis of existing data, or meta-analysis. Our internal advisory group will identify a strong theme from among the abstracts and, depending on the theme identified, will select projects from the abstracts of different investigators that can be incorporated to meet the requirement of 3 to 5 strong projects for the application to be submitted.

Ensuring appropriate leveraging of URMC research support services is essential to developing a competitive proposal. Please submit your 1- to 2-page abstract with a preliminary proposal to Harriet Kitzman of the Center for Research Implementation and Translation (CRIT) at by March 26. All submitted abstracts will undergo committee review and feedback will be provided. For planning purposes, please note that AHRQ does not require letters of intent for this FOA, and deadlines for submission of applications to AHRQ are June 19, 2012, December 19, 2012, December 19, 2013 and December 19, 2014. Details regarding submission format and mechanism, as well as further description of funding objectives are provided in the FOA (PA-12-114), found here.

The Clinical and Translational Science Institute can provide assistance to individuals interested in applying. Specific expertise is available in study design, participant recruitment, community involvement, program evaluation, training and other areas. Please contact for information.



NIH Funding Acknowledgement ** Important ** All publications resulting from the utilization of CTSI resources are required to credit the CTSI grant by including the NIH FUNDING ACKNOWLEDGEMENT and must comply with the NIH Public Access Policy.