URMC / Center for Vaccine Biology & Immunology / Publications Publications Murphy PSWang JBhagwat SPMunger JCJanssen WJWright TWElliott MR (2017 Mar). CD73 regulates anti-inflammatory signaling between apoptotic cells and endotoxin-conditioned tissue macrophages. Cell death and differentiation. Elliott MRKoster KMMurphy PS (2017 Feb 15). Efferocytosis Signaling in the Regulation of Macrophage Inflammatory Responses. Journal of immunology (Baltimore, Md. : 1950). Zent CSElliott MR (2016 Nov 14). Maxed out macs: physiologic cell clearance as a function of macrophage phagocytic capacity. The FEBS journal. Meli APFontés GAvery DTLeddon SATam MElliot MBallesteros-Tato AMiller JStevenson MMFowell DJTangye SGKing IL (2016 Oct 18). The Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance. Immunity. Lambert Emo KHyun YMReilly EBarilla CGerber SFowell DKim MTopham DJ (2016 Sep). Live Imaging of Influenza Infection of the Trachea Reveals Dynamic Regulation of CD8+ T Cell Motility by Antigen. PLoS pathogens. DeDiego MLNogales ALambert-Emo KMartinez-Sobrido LTopham DJ (2016 Aug 17). An NS1 protein mutation (I64T) affects interferon responses and virulence of circulating H3N2 human influenza A viruses. Journal of virology. Billroth-MacLurg ACFord JRosenberg AMiller JFowell DJ (2016 Aug 10). Regulatory T Cell Numbers in Inflamed Skin Are Controlled by Local Inflammatory Cues That Upregulate CD25 and Facilitate Antigen-Driven Local Proliferation. Journal of immunology (Baltimore, Md. : 1950). Elliott MRRavichandran KS (2016 Jul 25). The Dynamics of Apoptotic Cell Clearance. Developmental cell. Batchu SNHughson AWadosky KMMorrell CNFowell DJKorshunov VA (2016 Jun 30). Role of Axl in T-Lymphocyte Survival in Salt-Dependent Hypertension. Arteriosclerosis, thrombosis, and vascular biology. Jegaskanda SLuke CHickman HDSangster MYWieland-Alter WFMcBride JMYewdell JWWright PFTreanor JRosenberger CMSubbarao K (2016 Jun 28). The generation and protective ability of influenza-specific antibody-dependent cellular cytotoxicity in humans elicited by vaccination, natural infection or experimental challenge. The Journal of infectious diseases. Capece TKim M (2016 Jun 16). The Role of Lymphatic Niches in T Cell Differentiation. Molecules and cells. Pichichero MECasey JRAlmudevar ABasha SSurendran NKaur RMorris MLivingstone AMMosmann TR (2016 Jun 15). Functional Immune Cell Differences Associated With Low Vaccine Responses in Infants. The Journal of infectious diseases. Henry Dunand CJLeon PEHuang MChoi AChromikova VHo IYTan GSCruz JHirsh AZheng NYMullarkey CEEnnis FATerajima MTreanor JJTopham DJSubbarao KPalese PKrammer FWilson PC (2016 Jun 8). Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection. Cell host & microbe. DeDiego MLAnderson CSYang HHolden-Wiltse JFitzgerald TTreanor JJTopham DJ (2016 Jun). Directed selection of influenza virus produces antigenic variants that match circulating human virus isolates and escape from vaccine-mediated immune protection. Immunology. Nogales ADeDiego MLTopham DJMartínez-Sobrido L (2016 Apr 27). Rearrangement of influenza virus spliced segments for the development of live attenuated vaccines. Journal of virology. Surve CRTo JYMalik SKim MSmrcka AV (2016). Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits Gαi-GTP and Gβγ. Science signaling. Gaylo AOverstreet MGFowell DJ (2016). Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis. Journal of visualized experiments : JoVE. Nedelkovska HRosenberg AFHilchey SPHyrien OBurack WRQuataert SABaker CMAzadniv MWelle SLAnsell SMKim MBernstein SH (2016). Follicular Lymphoma Tregs Have a Distinct Transcription Profile Impacting Their Migration and Retention in the Malignant Lymph Node. PloS one. Yang HBaker SFGonzález METopham DJMartínez-Sobrido LZand MHolden-Wiltse JWu H (2016). An improved method for estimating antibody titers in microneutralization assay using green fluorescent protein. Journal of biopharmaceutical statistics. Rebhahn JARoumanes DRQi YKhan AThakar JRosenberg ALee FEQuataert SASharma GMosmann TR (2016 Jan). Competitive SWIFT cluster templates enhance detection of aging changes. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Aghaeepour NChattopadhyay PChikina MDhaene TVan Gassen SKursa MLambrecht BNMalek MMcLachlan GJQian YQiu PSaeys YStanton RTong DVens CWalkowiak SWang KFinak GGottardo RMosmann TNolan GPScheuermann RHBrinkman RR (2016 Jan). A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Brinkman RRAghaeepour NFinak GGottardo RMosmann TScheuermann RH (2016 Jan). Automated analysis of flow cytometry data comes of age. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Finak GLangweiler MJaimes MMalek MTaghiyar JKorin YRaddassi KDevine LObermoser GPekalski MLPontikos NDiaz AHeck SVillanova FTerrazzini NKern FQian YStanton RWang KBrandes ARamey JAghaeepour NMosmann TScheuermann RHReed EPalucka KPascual VBlomberg BBNestle FNussenblatt RBBrinkman RRGottardo RMaecker HMcCoy JP (2016). Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium. Scientific reports. DiPiazza ARichards KAKnowlden ZANayak JLSant AJ (2016). The Role of CD4 T Cell Memory in Generating Protective Immunity to Novel and Potentially Pandemic Strains of Influenza. Frontiers in immunology. Anderson CSDeDiego MLTopham DJThakar J (2016). Boolean Modeling of Cellular and Molecular Pathways Involved in Influenza Infection. Computational and mathematical methods in medicine. Knowlden ZASant AJ (2016). CD4 T cell epitope specificity determines follicular versus non-follicular helper differentiation in the polyclonal response to influenza infection or vaccination. Scientific reports. Anderson CSDeDiego MLThakar JTopham DJ (2016). Novel Sequence-Based Mapping of Recently Emerging H5NX Influenza Viruses Reveals Pandemic Vaccine Candidates. PloS one. Gaylo ASchrock DCFernandes NRFowell DJ (2016). T Cell Interstitial Migration: Motility Cues from the Inflamed Tissue for Micro- and Macro-Positioning. Frontiers in immunology. Reilly ECLambert-Emo KTopham DJ (2016). The Effects of Acute Neutrophil Depletion on Resolution of Acute Influenza Infection, Establishment of Tissue Resident Memory (TRM), and Heterosubtypic Immunity. PloS one. Scheible KMEmo JYang HHolden-Wiltse JStraw AHuyck HMisra STopham DJRyan RMReynolds AMMariani TJPryhuber GS (2015 Dec). Developmentally determined reduction in CD31 during gestation is associated with CD8+ T cell effector differentiation in preterm infants. Clinical immunology (Orlando, Fla.). Lim KHyun YMLambert-Emo KTopham DJKim M (2015 Nov). Visualization of integrin Mac-1 in vivo. Journal of immunological methods. Halliley JLKhurana SKrammer FFitzgerald TCoyle EMChung KYBaker SFYang HMartínez-Sobrido LTreanor JJSubbarao KGolding HTopham DJSangster MY (2015 Oct 15). High-Affinity H7 Head and Stalk Domain-Specific Antibody Responses to an Inactivated Influenza H7N7 Vaccine After Priming With Live Attenuated Influenza Vaccine. The Journal of infectious diseases. Rangel-Moreno Jde la Luz Garcia-Hernandez MRamos-Payan RBiear JHernady ESangster MYRandall TDJohnston CJFinkelstein JNWilliams JP (2015 Oct). Long-Lasting Impact of Neonatal Exposure to Total Body Gamma Radiation on Secondary Lymphoid Organ Structure and Function. Radiation research. Lim KHyun YMLambert-Emo KCapece TBae SMiller RTopham DJKim M (2015 Sep 4). Neutrophil trails guide influenza-specific CD8⁺ T cells in the airways. Science (New York, N.Y.). Leddon SARichards KATreanor JJSant AJ (2015 Sep). Abundance and specificity of influenza reactive circulating memory follicular helper and non-follicular helper CD4 T cells in healthy adults. Immunology. Boule LAWinans BLambert KVorderstrasse BATopham DJPavelka MSLawrence BP (2015 Aug 1). Activation of the aryl hydrocarbon receptor during development enhances the pulmonary CD4+ T-cell response to viral infection. American journal of physiology. Lung cellular and molecular physiology. Deng NMosmann TR (2015 Aug). Optimization of the cytokine secretion assay for human IL-2 in single and combination assays. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Baker SFNogales ASantiago FWTopham DJMartínez-Sobrido L (2015 Jul 9). Competitive detection of influenza neutralizing antibodies using a novel bivalent fluorescence-based microneutralization assay (BiFMA). Vaccine. Brinkman RRAghaeepour NFinak GGottardo RMosmann TScheuermann RH (2015 Jul). State-of-the-Art in the Computational Analysis of Cytometry Data. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Richards KANayak JChaves FADiPiazza AKnowlden ZAAlam STreanor JJSant AJ (2015 Jul 1). Seasonal Influenza Can Poise Hosts for CD4 T-Cell Immunity to H7N9 Avian Influenza. The Journal of infectious diseases. Misra RSShah SFowell DJWang HScheible KMisra SKHuyck HWyman CPRyan RMReynolds AMMariani TJKatzman PJPryhuber GS (2015 May). Preterm cord blood CD4⁺ T cells exhibit increased IL-6 production in chorioamnionitis and decreased CD4⁺ T cells in bronchopulmonary dysplasia. Human immunology. Nayak JLRichards KAYang HTreanor JJSant AJ (2015 May 1). Effect of influenza A(H5N1) vaccine prepandemic priming on CD4+ T-cell responses. The Journal of infectious diseases. Lee AJDas SRWang WFitzgerald TPickett BEAevermann BDTopham DJFalsey ARScheuermann RH (2015 May). Diversifying Selection Analysis Predicts Antigenic Evolution of 2009 Pandemic H1N1 Influenza A Virus in Humans. Journal of virology. Wu HMiao HXue HTopham DJZand M (2015 May 1). Quantifying Immune Response to Influenza Virus Infection via Multivariate Nonlinear ODE Models with Partially Observed State Variables and Time-Varying Parameters. Statistics in biosciences. Kvistborg PGouttefangeas CAghaeepour NCazaly AChattopadhyay PKChan CEckl JFinak GHadrup SRMaecker HTMaurer DMosmann TQiu PScheuermann RHWelters MJFerrari GBrinkman RRBritten CM (2015 Apr 21). Thinking outside the gate: single-cell assessments in multiple dimensions. Immunity. Na BRKim HRPiragyte IOh HMKwon MSAkber ULee HSPark DSSong WKPark ZYIm SHRho MCHyun YMKim MJun CD (2015 Apr 13). TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse. The Journal of cell biology. Das SSarkar AChoudhury SSOwen KACastillo VFox SEckmann LElliott MRCasanova JEErnst PB (2015 Apr 1). ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome. Cellular and molecular gastroenterology and hepatology. Tankam PHe ZChu YJWon JCanavesi CLepine THindman HBTopham DJGain PThuret GRolland JP (2015 Mar 15). Assessing microstructures of the cornea with Gabor-domain optical coherence microscopy: pathway for corneal physiology and diseases. Optics letters. Haynes-Gimore NBanach MBrown EDawes REdholm ESKim MRobert J (2015 Jan 16). Semi-solid tumsor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration. Developmental biology. Sundararajan ASangster MYFrey SAtmar RLChen WHFerreira JBargatze RMendelman PMTreanor JJTopham DJ (2015 Jan 15). Robust mucosal-homing antibody-secreting B cell responses induced by intramuscular administration of adjuvanted bivalent human norovirus-like particle vaccine. Vaccine. Lerman YVKim M (2015). Neutrophil migration under normal and sepsis conditions. Cardiovascular & hematological disorders drug targets. Ramon SBaker SFSahler JMKim NFeldsott EASerhan CNMartínez-Sobrido LTopham DJPhipps RP (2014 Dec 15). The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: a new class of adjuvant? Journal of immunology (Baltimore, Md. : 1950). Lerman YVLim KHyun YMFalkner KLYang HPietropaoli APSonnenberg ASarangi PPKim M (2014 Dec 4). Sepsis lethality via exacerbated tissue infiltration and TLR-induced cytokine production by neutrophils is integrin α3β1-dependent. Blood. Babu TMLevine MFitzgerald TLuke CSangster MYJin HTopham DKatz JTreanor JSubbarao K (2014 Nov 28). Live attenuated H7N7 influenza vaccine primes for a vigorous antibody response to inactivated H7N7 influenza vaccine. Vaccine. Guo HBaker SFMartínez-Sobrido LTopham DJ (2014 Oct). Induction of CD8 T cell heterologous protection by a single dose of single-cycle infectious influenza virus. Journal of virology. Bobo BPhelan DRebhahn JPiepenbrink MSZheng BMosmann TRKobie JJDeLouise LA (2014 Sep 21). Microbubble array diffusion assay for the detection of cell secreted factors. Lab on a chip. Nogales ABaker SFOrtiz-Riaño EDewhurst STopham DJMartínez-Sobrido L (2014 Sep). Influenza A virus attenuation by codon deoptimization of the NS gene for vaccine development. Journal of virology. Baker SFNogales AFinch CTuffy KMDomm WPerez DRTopham DJMartínez-Sobrido L (2014 Sep). Influenza A and B virus intertypic reassortment through compatible viral packaging signals. Journal of virology. Rebhahn JADeng NSharma GLivingstone AMHuang SMosmann TR (2014 Aug). An animated landscape representation of CD4+ T-cell differentiation, variability, and plasticity: insights into the behavior of populations versus cells. European journal of immunology. Stevenson Cde la Rosa GAnderson CSMurphy PSCapece TKim MElliott MR (2014 Jun 15). Essential role of Elmo1 in Dock2-dependent lymphocyte migration. Journal of immunology (Baltimore, Md. : 1950). Baik SHCha MYHyun YMCho HHamza BKim DKHan SHChoi HKim KHMoon MLee JKim MIrimia DMook-Jung I (2014 Jun). Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model. Neurobiology of aging. Mosmann TRNaim IRebhahn JDatta SCavenaugh JSWeaver JMSharma G (2014 May). SWIFT-scalable clustering for automated identification of rare cell populations in large, high-dimensional flow cytometry datasets, part 2: biological evaluation. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Naim IDatta SRebhahn JCavenaugh JSMosmann TRSharma G (2014 May). SWIFT-scalable clustering for automated identification of rare cell populations in large, high-dimensional flow cytometry datasets, part 1: algorithm design. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Xu YHyun YMLim KLee HCummings RJGerber SABae SCho TYLord EMKim M (2014 Apr 29). Optogenetic control of chemokine receptor signal and T-cell migration. Proceedings of the National Academy of Sciences of the United States of America. Polesskaya OWong CLebron LChamberlain JMGelbard HAGoodfellow VKim MDaiss JLDewhurst S (2014 Apr). MLK3 regulates fMLP-stimulated neutrophil motility. Molecular immunology. Shi GField DJKo KATure SSrivastava KLevy SKowalska MAPoncz MFowell DJMorrell CN (2014 Feb). Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection. The Journal of clinical investigation. Knowlden SACapece TPopovic MChapman TJRezaee FKim MGeoras SN (2014). Regulation of T cell motility in vitro and in vivo by LPA and LPA2. PloS one. Miao HSangster MYLivingstone AMHilchey SPZhang LTopham DJMosmann TRHolden-Wiltse JPerelson ASWu HZand MS (2014). Modeling the dynamics and migratory pathways of virus-specific antibody-secreting cell populations in primary influenza infection. PloS one. Sanchez-Lockhart MRojas AVFettis MMBauserman RHiga TRMiao HWaugh REMiller J (2014). T cell receptor signaling can directly enhance the avidity of CD28 ligand binding. PloS one. Deng NWeaver JMMosmann TR (2014). Cytokine diversity in the Th1-dominated human anti-influenza response caused by variable cytokine expression by Th1 cells, and a minor population of uncommitted IL-2+IFNγ- Thpp cells. PloS one. Alam SKnowlden ZASangster MYSant AJ (2014 Jan). CD4 T cell help is limiting and selective during the primary B cell response to influenza virus infection. Journal of virology. Berry CMPenhale WJSangster MY (2014). Passive broad-spectrum influenza immunoprophylaxis. Influenza research and treatment. Weilhammer DRBlanchette CDFischer NOAlam SLoots GGCorzett MThomas CLychak CDunkle ADRuitenberg JJGhanekar SASant AJRasley A (2013 Dec). The use of nanolipoprotein particles to enhance the immunostimulatory properties of innate immune agonists against lethal influenza challenge. Biomaterials. Chen JPompano RRSantiago FWMaillat LSciammas RSun THan HTopham DJChong ASCollier JH (2013 Nov). 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Journal of immunology (Baltimore, Md. : 1950). Sharma SKRoumanes DAlmudevar AMosmann TRPichichero ME (2013 Jun 26). CD4+ T-cell responses among adults and young children in response to Streptococcus pneumoniae and Haemophilus influenzae vaccine candidate protein antigens. Vaccine. Sangster MYBaer JSantiago FWFitzgerald TIlyushina NASundararajan AHenn ADKrammer FYang HLuke CJZand MSWright PFTreanor JJTopham DJSubbarao K (2013 Jun). B cell response and hemagglutinin stalk-reactive antibody production in different age cohorts following 2009 H1N1 influenza virus vaccination. Clinical and vaccine immunology : CVI. Ball CJReiffel AJChintalapani SKim MSpector JAKing MR (2013 Mar). Hydrogen sulfide reduces neutrophil recruitment in hind-limb ischemia-reperfusion injury in an L-selectin and ADAM-17-dependent manner. Plastic and reconstructive surgery. Aghaeepour NFinak G Hoos HMosmann TRBrinkman RGottardo RScheuermann RH (2013 Mar). 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