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Thesis Defenses

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Inflammation in Osteoarthritis Pathogenesis: Contribution of IKKB/NF-KB Signaling and Interplay with Chondrocyte Hypertrophy

Sarah Catheline - Pathology PhD Candidate

 Dec 18, 2018 @ 2:00 p.m.

 Medical Center | Lower Adolph Auditorium (1-7619, URMC)

Host: Dr. Jennifer Jonason

Thermodynamic and Structural Studies of RNA Internal Loops Closed by GU Pairs

Kyle Berger - Biophysics PhD Candidate

 Dec 18, 2018 @ 2:00 p.m.

 Medical Center | Neuman Room (1-6823)

Host: Dr. Douglas Turner

Impact of tumor hypoxia on immune response: implication for radiotherapy and anti-tumor immunity

Aditi Murthy - Microbiology & Immunology PhD Candidate

 Dec 12, 2018 @ 9:30 a.m.

 Medical Center | Auditorium K-307 (3-6408, URMC)

Host: Dr. Edith Lord

Defining Functional Roles for the Rhamnose-glucose Polysaccharides of Streptococcus mutans

Christopher Kovacs - Microbiology & Immunology PhD Candidate

 Dec 07, 2018 @ 1:00 p.m.

 Medical Center | Upper Adolph Auditorium (3-7619, URMC)

Host: Dr. Robert Quivey

Inflammation and Cognitive Function in Chronic Lymphocytic Leukemia Survivors

AnnaLynn Williams - Epidemiology PhD Candidate

 Dec 07, 2018 @ 1:00 p.m.

 Helen Wood Hall | 1W 509

Host: Dr. Edwin van Wijngaarden

Chronic PKC-beta-II activation inhibits IKs channel membrane localization via phosphatidylinositol 4-phosphate: Implications for Long-QT1 treatment

Chen Braun - Pharmacology PhD Candidate

 Dec 05, 2018 @ 1:00 p.m.

 Medical Center | Ryan Case Method Room (1-9576)

Host: Dr. Coeli Lopes

Paxillin Regulates Genomic Networks in Prostate Cancer

Xiaoting Ma - Pathology PhD Candidate

 Nov 29, 2018 @ 2:00 p.m.

 Medical Center | Auditorium K 307 (3-6408, URMC)

Host: Dr. Stephen Hammes

Targeting the c-Cbl Tumor Suppressor Protein as a Novel Therapeutic Approach in Overcoming Acquired Tamoxifen Resistance in Luminal Breast Cancer

Xiaowen Wang - Pharmacology PhD Candidate

 Nov 27, 2018 @ 1:00 p.m.

 Medical Center | Lower Adolph Auditorium (1-7619, URMC)

Host: Dr. Mark Noble

Targeting the c-Cbl Tumor Suppressor Protein as a Novel Therapeutic Approach in Overcoming Acquired Tamoxifen Resistance in Luminal Breast Cancer

Xiaowen (Cindy) Wang - PhD Candidate - Pharmacology, Advisor: Dr. Mark Noble

 Nov 27, 2018 @ 1:00 p.m.

 Medical Center | Adolph Auditorium 1-7619

Mechanism Regulating Trachea-Esophageal Separation

Eugene Kim - PhD Candidate - Genetics, Advisor: Dr. Jianwen Que

 Nov 09, 2018 @ 1:00 p.m.

 Medical Center | Upper Auditorium 3-7619

Regulation of Stem Cell Proliferation and Differentiation by Drosophila Sox21a and Sox100B in the Adult Intestine

Fanju Meng - PhD Candidate - Genetics, Advisor: Dr. Benoit Biteau

 Nov 08, 2018 @ 3:00 p.m.

 Medical Center | Adolph Lower Auditorium 1-7619

Modeling RNA Secondary Structure Using Structure Conservation

Zhen Tan - PhD Candidate - Biophysics, Advisor: Dr. David Mathews

 Nov 02, 2018 @ 12:00 p.m.

 Medical Center | Neuman Room

Recurrent DNA damage following single dose whole thorax irradiation is associated with a pro-fibrotic phenotype in the pulmonary epithelium

Tyler A. Beach - PhD Candidate - Toxicology, Advisor: Dr. Jacob Finkelstein

 Oct 25, 2018 @ 9:00 a.m.

 Medical Center | Whipple Auditorium (2-6424)

Thy1 (CD90) is a novel regulator of adipogenesis and is a target of obesogenic environmental chemicals

E'Lissa Marie Flores - PhD Candidate - Translational Biomedical Science, Advisor: Dr. Craig Morrell

 Sep 07, 2018 @ 1:30 p.m.

 Medical Center | Adolph Lower Auditorium 1-7619

Exploring the evolutionary relevance of MHC class 1-like molecules and innate-like Tcells in Xenopus tumor immunity

Maureen Ludmila Banach - PhD Candidate - Microbiology & Immunology, Advisor: Dr. Jacques Robert

 Aug 21, 2018 @ 1:00 p.m.

 Medical Center | K307 (3-6408)

Understanding Differences in Cardiovascular Care for Acute Myocardial Infarction Patients with a Comorbid Mental Illness

Chelsea Lyons Katz - PhD candidate - Health Services Research & Policy, Advisor: Dr. Peter Veazie

 Aug 17, 2018 @ 1:00 p.m.

 Helen Wood Hall | HWH 1W-509

Effects of P2Y2 Signaling on Regulation of Efferocytosis and CXCR4 Internalization

Taylor J. Moon - PhD Candidate - Microbiology & Immunology, Advisor: Dr. Michael R. Elliott

 Aug 15, 2018 @ 1:00 p.m.

 Medical Center | Lower Auditorium 1-7619

Chemokine Independent CD8+ T cell Migration

Brandon L. Walling - PhD Candidate - Microbiology & Immunology, Advisor: Dr. Minsoo Kim

 Aug 14, 2018 @ 10:00 a.m.

 Medical Center | K307 (3-6408)

Characterization of tRNA Quality Control Pathways in Yeast

Matthew John Payea - PhD Candidate - Biochemistry, Advisor: Dr. Eric Phizicky

 Jul 24, 2018 @ 1:00 p.m.

 Medical Center | Neuman Room (1-6823)

Cooperative and mechanistic roles of Mecom in hematopoiesis

Kelly A. McGlynn - PhD Candidate - Pharmacology, Advisor: Dr. Archibald Perkins

 Jun 25, 2018 @ 3:00 p.m.

 Medical Center | Case Method Room, 1-9576

The Dichotomy of Curaxin Compounds in HIV-1 Latency

Maxime Junior Jean - PhD Candidate - Microbiology & Immunology, Advisor: Dr. Jian Zhu

 Jun 20, 2018 @ 3:00 p.m.

 Medical Center | K-207 2-6408

Progenitor cell contribution to maintenance and regeneration in salivary gland and olfactory epithelium

Pei-Lun Weng - PhD Candidate - Pathology, Advisor: Dr. Catherine Ovitt

 Jun 20, 2018 @ 1:30 p.m.

 Medical Center | K-307 3-6408

Specificity determinants of homologous VapBC toxin-antitoxin systems

Lauren Rice Walling - PhD Candidate - Microbiology & Immunology, Advisor: Dr. Scott Butler

 Jun 12, 2018 @ 11:00 a.m.

 Medical Center | Whipple Auditorium, 2-6424

The Role of Serpin B13 Antibody in Regeneration of Pancreatic B-cells

Chi-Wen Lo - PhD Candidate - Pathology, Advisor: Dr. Jan Czyzyk

 Jun 06, 2018 @ 2:00 p.m.

 Medical Center | K-207 1-6408

Novel Statistical Methods for Gene Set Enrichment Analysis with Empirical Memberships for Overlapping Genes

Yun Zhang - PhD Candidate - Statistics, Advisor: Dr. Xing Qiu

 May 31, 2018 @ 2:00 p.m.

 Saunders Research Bulding | 1416

Midbrain Axonal Injury is the Signature Neurotrauma of Subconcussion and Concussion

Adnan A. Hirad - PhD Candidate - Translational Biomedical Science, Advisor: Dr. Jeff Bazarian

 May 29, 2018 @ 1:00 p.m.

  | 1-9576

The Impact of Hospital Share of Nursing Home-originating Hospitalizations and Nursing Home Quality on 30-day Readmission Rates

Zhiqiu (Qiuqiu) Ye - PhD Candidate - Health Services Research & Policy, Advisor: Dr. Orna Intrator

 May 25, 2018 @ 11:00 a.m.

 Saunders Research Bulding | 1416

Lmx1a is required for Drosophila ovary stem cell niche formation and organogenesis

Andrew Allbee - PhD candidate - Genetics, Advisor: Dr. Benoit Biteau

 Apr 27, 2018 @ 3:00 p.m.

 Medical Center | 1-7619 Adolph (Lower) Auditorium

Disproportionate Premature Birth in Women of Low Socioeconomic Status: A Psychological and Physiological Stress Explanation of Financial Risk Removal

Nicolas Patrick Novick Goldstein - PhD candidate - Health Services Research and Policy, Advisor: Dr. Peter Veazie

 Apr 24, 2018 @ 12:00 p.m.

 Helen Wood Hall | 1W304

Thesis Defense: Region-specific Proteolysis Differentially Regulates Inositol 1,4,5-trisphosphate Receptor Activity

Liwei Wang - PhD candidate - Pharmacology, Advisor: Dr. David Yule

 Apr 23, 2018 @ 2:30 p.m.

 Medical Center | Case Method Room (1-9576)

Thesis Defense Seminar: Aryl hydrocarbon receptor activation during development reduces dendritic cell function later in life

Jessica L. Meyers - PhD candidate, Toxicology

 Apr 19, 2018 @ 1:00 p.m.

 Medical Center | Adolph Auditorium, 1-7619

Host: B. Paige Lawrence, Ph.D.

Neutrophil Elastase and SERPINB1 are Critical Regulators of Prostate Cancer Progression

Irina Lerman - PhD candidate - Pathology, Advisor: Dr. Stephen Hammes

 Apr 17, 2018 @ 2:00 p.m.

 Medical Center | 3-6408 K 307

Pump Independent Functions of the Na+, K+ -ATPase B1 Subunit in Restoring Alveolar Epithelial Barrier

Haiqing Bai - PhD candidate - Pathology, Advisor: Dr. David A. Dean

 Apr 16, 2018 @ 1:30 p.m.

 Medical Center | 3-6408 K 307

The Dynamic Role of SOX2 in Mammalian Inner Ear Development

Aleta Steevens - PhD Candidate - Neuroscience, Advisor: Dr. Amy Kiernan

 Apr 16, 2018 @ 12:00 p.m.

 Medical Center | Ryan Case Method Room (1-9576)

Elucidating the Role of Cholesterol in Respiratory RNA Virus Infection and Transmission

Shringkhala Bajimaya - PhD candidate - Microbiology & Immunology, Advisor: Dr. Toru Takimoto

 Apr 13, 2018 @ 1:15 p.m.

 Medical Center | Adolph Auditorium, 1-7619

Mitochondrial Metabolism in Cardiac Ischemia-Reperfusion Injury

Jimmy Zhang - PhD Candidate - Physiology, Advisor: Dr. Paul Brookes

 Apr 11, 2018 @ 1:00 p.m.

 Medical Center | Neuman Room (1-6823)

Reproductive and Sexual Functioning after Mild Traumatic Brain Injury (mTMI) in Woman

Martina Afia Magdalena Anto-Ocrah - PhD Candidate - Epidemiology, Advisor: Dr. Edwin van Wijngaarden

 Apr 10, 2018 @ 1:00 p.m.

 Helen Wood Hall | 1W502

Mechanistic Analysis of Influenza A Virus Assembly and Host Gene Regulation

Chutikarn Chaimayo - PhD candidate - Microbiology & Immunology, Advisor: Dr. Toru Takimoto

 Apr 06, 2018 @ 1:30 p.m.

 Medical Center | Upper Auditorium (Room 3-7619)

Insights into G protein ?? Regulation of Phospholipase C?

Jerry Chukwuemeka Madukwe - PhD candidate - Biochemistry, Advisor: Dr. Alan Smrcka

 Apr 02, 2018 @ 1:00 p.m.

 Medical Center | Neuman Room (1-6823)

Mitochondrial Metabolism in Bone Physiology and Pathology

Laura C. Shum - PhD candidate - Translational Biomedical Science, Advisor: Dr. Roman Eliseev

 Mar 28, 2018 @ 10:00 a.m.

 Medical Center | 1-7619 Adolph (Lower) Auditorium

The Importance of G Protein Signaling in Immune Cell Function: A Novel Role for Active G Protein ?i in Cell Adhesion and Migration and the Therapeutic Potential of Targeting G?? in Inflammation

Jesi Lee Anne Y. To - PhD candidate - Pharmacology, Advisor: Dr. Alan Smrcka

 Mar 22, 2018 @ 1:00 p.m.

 Medical Center | K-207, 2-6408

KNa1.2 as a Cardiac Mitochondrial Potassium Channel with Metabolic Impact on Energy Usage

Charles Owen Smith - PhD candidate - Biochemistry

 Mar 06, 2018 @ 9:30 a.m.

 Medical Center | Neuman Room (1-6823)

Host: Dr. Paul Brookes (Advisor)

The Role of PLC-Dependent Hydrolysis of Phosphatidylinositol 4-Phosphate in Signaling and Disease

Rafael Gil de Rubio - PhD candidate - Pharmacology

 Mar 05, 2018 @ 2:00 p.m.

 Medical Center | Ryan Case Method Room (1-9576)

Host: Dr. Alan Smrcka (Advisor)

An Nrf1 and Nrf2- related transcription factor, Cnc-C, mediates multiple stress responses in Drosophila melanogaster

Min Tian - PhD candidate - Pathology

 Mar 01, 2018 @ 2:30 p.m.

 Medical Center | 1-7619 Lower Adolph

Host: Dr. Dirk Bohmann (Advisor

“The Adhesion GPCR, GPR56/ADGRG1, Inhibits Cell-ECM Signaling to Prevent Metastatic Melanoma Growth”

Michalle Warren Millar - PhD candidate - Genetics

 Feb 27, 2018 @ 1:00 p.m.

 Medical Center | 1-7619 Adolph (Lower) Aud

Cigarette Smoke Dysregulates innate-immune responses in Epithelial Cells to Viral Infection

Parker F. Duffney - Toxicology PhD Candidate

 Feb 27, 2018 @ 10:00 a.m.

 Medical Center | 3-7619 Upper Auditorium

Host: Dr. Patricia Sime

“Genetic and Pharmacological Regulation of Epigenetic Aging”

Yang Cheng - PhD candidate - Genetics

 Feb 27, 2018 @ 9:30 a.m.

 Medical Center | K307 (3-6408)

Consequences of Developmental Ethanol Exposure on Synaptic Plasticity, Microglial Phenotype, and Dendritic Spine Dynamics

Elissa Li-yee Wong - Toxicology PhD Candidate

 Feb 07, 2018 @ 1:00 p.m.

 Medical Center | 1-9576 Case Method Room

Host: Dr. Ania K. Majewska

Investigation into the roles of vaccinia virus protein F13 and its molluscum contagiosum virus homolog MC021

Peter Joseph Bryk - Microbiology & Immunology PhD Candidate

 Jan 26, 2018 @ 12:00 p.m.

 Medical Center | Upper Aud 3-7619

The Biology of Anticodon Stem-Loop Modifications of Yeast tRNAs

Lu Han - Biochemistry PhD Candidate

 Jan 23, 2018 @ 2:00 p.m.

 Medical Center | Neuman Room (1-6823)

STAT3 regulates primitive erythroid maturation both dependent and independently of erythropoietin signaling

Zachary Murphy - Pathology PhD Candidate

 Jan 18, 2018 @ 1:00 p.m.

  | 1-7619 Lower Adolph