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Education / Graduate Education / PhD Programs / Biochemistry & Molecular Biology

Biochemistry & Molecular Biology

The Biochemistry & Molecular Biology (BMB) Program is designed for students interested in obtaining a Ph.D. in Biochemistry. As such, the program represents a group of faculty that may mentor a student pursuing thesis research toward the Biochemistry Ph.D. Students interested in a Ph.D. in Biochemistry should apply to the Biochemistry & Molecular Biology Program for admission to graduate studies at the University of Rochester Medical Center.

Chenguang Gong in Maquat Lab

Chenguang Gong working in the Maquat Lab

We offer in-depth coursework and diverse research opportunities that focus on understanding the biochemical mechanisms of life’s critical molecular processes.

World-class research in our laboratories exposes our students to a variety of the latest methods for sophisticated biochemical analysis, including mass spectrometry, crystallography, microcalorimetry, surface plasmon resonance, microarrays, fluorescence activated cell sorting, light scattering, and spectroscopic methods (including fluorescence lifetime and energy transfer measurements), as well as modern methods for cell culture, protein purification, genetic analysis, and reconstitution of biochemical complexes and reactions.

The flexibility of our training program allows students to train in a number of exciting research areas, and often allows students to develop highly effective interdisciplinary collaborations, resulting in cutting edge thesis projects.

NIH T32 Sponsored Programs

Training Grant in Cellular, Biochemical & Molecular Sciences

Graduate Women in Science (GWIS)

Research

We have several research areas, fully supported by an array of labs and centers. For a full view of our research efforts and Facilities, see our research page.

For a list of recent student publications, please visit the student publications page.

 

Events

Upcoming20172016201520142013

Date/TimeLocationTitle/Presenter/Affiliation
Jan 17, 2013
1:00 p.m.
Medical Center G-9425 (Class of '62 Aud.)Development of Next-Gen PCR Technologies
Phillip Belgrader, Ph.D.
R&D Manager, Bio-Rad (formerly QuantaLife)
Feb 20, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Assembly and Dynamics of Uber Complex RNPs
Melissa Moore, Ph.D.
Investigator, Howard Hughes Medical Institute; Co-Director, RNA and Neuro Therapeutics Institutes; Professor, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School
Feb 27, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Activation of the G Protein Coupled Receptor Rhodopsin: From Femtoseconds to Seconds
Oliver Ernst, Ph.D.
Professor, Department of Biochemistry, University of Toronto
Mar 07, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Assessing and Validating Simulation Approaches to Model Nucleic Acid Structure and RNA-Ligand Interactions
Thomas Cheatham, III, Ph.D.
Associate Professor, Department of Medicinal Chemistry, College of Pharmacy, University of Utah
Mar 13, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Reversible DNA and RNA Methylation in Biological Regulation
Chuan He, Ph.D.
Professor, Department of Chemistry; Director, Institute for Biophysical Dynamics, University of Chicago
Mar 20, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Modulation of Folding Energy Landscape by Charge-Charge Interactions: Linking Experiments with Computational Modeling
George Makhatadze, Ph.D.
Senior Constellation Chaired Professor in Biocomputation and Bioinformatics; Professor, Department of Biology, Chemistry and Chemical Biology, Rensselaer Polytechnic Institute
Mar 27, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)The Role of MicroRNAs in Cancer: Cross-Talk with Antioxidant Genes
Jozef Dulak, Ph.D. D.Sc.
Professor and Head, Department of Medical Biotechnology, Jagiellonian University, Poland
Apr 03, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)mRNA Surveillance is Driven by Translation
Rachel Green, Ph.D.
Investigator, Howard Hughes Medical Institute; Professor, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine
Apr 10, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Cancer Metabolism: Cell Biology and Translational Opportunities
Ralph DeBerardinis, M.D. Ph.D.
Assistant Professor, Department of Pediatrics and Genetics, University of Texas Southwestern Medical Center
Apr 17, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Cryo-EM with Movies: Higher Resolution with Optimized Image Contrast
Nikolaus Grigorieff, Ph.D.
Investigator, Howard Hughes Medical Institute; Professor, Department of Biochemistry, Brandeis University
Apr 24, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Using Computer Simulations to Investigate Dynamic Aspects of Inhibitor Binding and Potency
Carlos Simmerling, Ph.D.
Professor, Department of Chemistry, SUNY Stony Brook
May 01, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)The Structure and Viral Recognition Mechanisms of Surveillance Protein RIG-I
Anna Marie Pyle, Ph.D.
Investigator, Howard Hughes Medical Institute; Professor, Departments of Molecular, Cellular & Developmental Biology and Department of Chemistry, Yale University
May 08, 2013
1:00 p.m.
Medical Center G-9425 (Class of '62 Aud.)Structure and Dynamics of the Ribosome
Harry Noller, Ph.D.
Director, Center of Molecular Biology of RNA, University of California, Santa Cruz
May 22, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Circadian Components as Modulators of Cell Cycle Signaling
Carla Finkielstein, Ph.D.
Associate Professor, Department of Biological Sciences, Virginia Polytechnic Institute
May 29, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Controlling Biology By Protein Design
Shohei Koide, Ph.D.
Professor, Department of Biochemistry and Molecular Biology, The University of Chicago
Jul 15, 2013
4:00 p.m.
Medical Center 3-6408 (K-307)APOBEC3 Proteins: role in sexual transmission of retroviruses
Chioma Okeoma, Ph.D.
Assistant Professor, Department of Microbiology and Interdisciplinary Graduate Program in Molecular & Cellular Biology, The University of Iowa
Jul 17, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Adapting to Stress: Lessons from a Model Organism
James R. Broach, Ph.D.
Director, Penn State Hershey Institute for Personalized Medicine, Chair, Department of Biochemistry and Molecular Biology at Penn State Professor Emeritus of Princeton University
Aug 07, 2013
10:00 a.m.
Medical Center 1-6823 (Neuman Conference Room)Trinucleotide Repeat Instability via DNA Base Lesion Repair
Yuan Liu, Ph.D.
Assistant Professor, Department of Chemistry and Biochemistry School of Integrated Science and Humanity Florida International University
Sep 18, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)The Importance of Being Modified: How Modified Nucleosides Influence Codon Usage
Paul Agris, Ph.D.
Professor, Department of Biological Sciences and Chemistry; Director, The RNA Institute; SUNY Albany
Sep 23, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Neurexins - Synaptic Organizers Implicated in Neurological Disease
Gabrielle Rudenko, Ph.D.
Research Assistant Professor, Life Sciences Institute; Assistant Professor, Department of Pharmacology; University of Michigan Medical School
Sep 25, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)The Role of PARP-1 in Chromatin-Mediated Gene Regulation: Control of Cellular Signaling and Differentiation Programs
W. Lee Kraus, Ph.D.
Director, Cecil H. and Ida Green Center for Reproductive Biology Sciences; Professor and Vice Chair for Basic Science, Department of Ob/Gyn; Professor, Department of Pharmacology; Cecil H. and Ida Green Distinguished Chair in Reproductive Biology Sciences; UT Southwestern Medical Center at Dallas
Oct 02, 2013
2:00 p.m.
Medical Center G-9425 (Class of '62 Aud.)Normal and Unusual Decoding by the Ribosome
Venkatraman Ramakrishnan, Ph.D.
Medical Research Council Laboratory of Molecular Biology; Cambridge Biomedical Campus; Cambridge, England
Oct 09, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Clock Proteins: New Players in DNA-Damage Signaling
Carla Finkielstein, Ph.D.
Associate Professor, Department of Biological Sciences; Virginia Polytechnic Institute
Oct 16, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Spliceosome Assembly and Activity
Andrew MacMillan, Ph.D.
Professor, Department of Biochemistry; University of Alberta
Oct 21, 2013
3:00 p.m.
Medical Center 2-6408 (K-207 Aud)Identification of a New RNA Degradation Machine: A Bedside to Bench Story
Sandra Wolin, M.D.,Ph.D.
Professor of Cell Biology and Molecular Biophysics and Biochemistry and Vice Chair of the Department of Cell Biology, Yale University School of Medicine
Oct 23, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Using Computer Simulations to Investigate Dynamic Aspects of Inhibitor Binding and Potency
Carlos Simmerling, Ph.D.
Professor, Department of Chemistry; SUNY Stony Brook
Oct 30, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)When Chromatin Assembly Goes Awry
Jessica Tyler, Ph.D.
Professor, Department of Biochemistry and Molecular Biology; The University of Texas MD Anderson Cancer Center
Nov 06, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Test Driving the 60S Ribosomal Subunit
Arlen Johnson, Ph.D.
Professor, Department of Molecular Biosciences; The University of Texas at Austin
Nov 20, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)RNA Sensors and Global Metabolic Regulation
Martha Fedor, Ph.D.
Editor in Chief, Journal of Biological Chemistry; Professor, Department of Chemical Physiology, Department of Cell and Molecular Biology, and The Skaggs Institute for Chemical Biology; The Scripps Research Institute
Nov 21, 2013
1:00 p.m.
Medical Center G-9425 (Class of '62 Auditorium)Communicating Science in the 21st Century
Martha Fedor, Ph.D.
Editor in Chief, Journal of Biological Chemistry; Professor, Department of Chemical Physiology, Department of Cell and Molecular Biology, and The Skaggs Institute for Chemical Biology; The Scripps Research Institute
Nov 21, 2013
3:00 p.m.
Medical Center 1-9576 (Case Method Room)An Unforeseen Path to a Fortuitous End
Martha Fedor, Ph.D.
Editor in Chief, Journal of Biological Chemistry; Professor, Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA
Dec 18, 2013
2:00 p.m.
Medical Center 3-6408 (K-307)Structural Insights into Novel Deoxysugar Biosynthesis in Bacteria
Hazel Holden, Ph.D.
Professor, Department of Biochemistry; University of Wisconsin-Madison

Event Photos