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Education / Graduate Education / PhD Programs / Biochemistry & Molecular Biology

Biochemistry & Molecular Biology

The Biochemistry & Molecular Biology (BMB) Program is designed for students interested in obtaining a Ph.D. in Biochemistry. As such, the program represents a group of faculty that may mentor a student pursuing thesis research toward the Biochemistry Ph.D. Students interested in a Ph.D. in Biochemistry should apply to the Biochemistry & Molecular Biology Program for admission to graduate studies at the University of Rochester Medical Center.

Chenguang Gong in Maquat Lab

Chenguang Gong working in the Maquat Lab

We offer in-depth coursework and diverse research opportunities that focus on understanding the biochemical mechanisms of life’s critical molecular processes.

World-class research in our laboratories exposes our students to a variety of the latest methods for sophisticated biochemical analysis, including mass spectrometry, crystallography, microcalorimetry, surface plasmon resonance, microarrays, fluorescence activated cell sorting, light scattering, and spectroscopic methods (including fluorescence lifetime and energy transfer measurements), as well as modern methods for cell culture, protein purification, genetic analysis, and reconstitution of biochemical complexes and reactions.

The flexibility of our training program allows students to train in a number of exciting research areas, and often allows students to develop highly effective interdisciplinary collaborations, resulting in cutting edge thesis projects.

NIH T32 Sponsored Programs

Training Grant in Cellular, Biochemical & Molecular Sciences

Graduate Women in Science (GWIS)

Research

We have several research areas, fully supported by an array of labs and centers. For a full view of our research efforts and Facilities, see our research page.

For a list of recent student publications, please visit the student publications page.

 

Events

Upcoming20172016201520142013

Student Seminar (BCH 502/BPH 572) for Sarah Loerch

Sarah Loerch - PhD Candidate
Jan 27, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Christina Brule and Clarence Ling

Christina Brule & Clarence Ling - PhD Candidates
Feb 03, 2015 - 1:00 p.m.
Medical Center 1-7619 (Adolph Auditorium)

Student Seminar (BCH 502/BPH 572) for Rakesh Chatrikhi and Jerry Madukwe

Rakesh Chatrikhi & Jerry Madukwe - PhD Candidates
Feb 10, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Rakesh Chatrikhi and Jerry Madukwe

Rakesh Chatrikhi & Jerry Madukwe - PhD Candidates
Feb 10, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Regulated mRNA Modification: A New Function for Ancient RNA-Modifying Enzymes

Wendy Gilbert, Ph.D. - Associate Professor, Department of Biology, MIT, Cambridge, MA
Feb 11, 2015 - 2:00 p.m.
Medical Center K-307 (3-6408)
Host: Dr. Yi-Tao Yu

Student Seminar (BCH 502/BPH 572) for Morgan Monaghan and Thomas Hilimire

Morgan Monaghan & Thomas Hilimire - PhD Candidates
Feb 17, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Morgan Monaghan and Thomas Hilimire

Morgan Monaghan & Thomas Hilimire - PhD Candidates
Feb 17, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

How Cells Integrate Transcription and Splicing to Accomplish Gene Expression on Time

Karla Neugebauer, Ph.D. - Professor, Department of Molecular Biophysics and Biochemistry, Yale University
Feb 18, 2015 - 2:00 p.m.
Medical Center 3-6408 (K-307)
Host: Dr. Lynne Maquat

Student Seminar (BCH 502/BPH 572) for Mallory Scott and Matthew Payea

Mallory Scott & Matthew Payea - PhD Candidates
Feb 24, 2015 - 1:00 p.m.
Medical Center Ryan Case Method Room (1-9576)

Student Seminar (BCH 502/BPH 572) for Mallory Scott and Matthew Payea

Mallory Scott & Matthew Payea - PhD Candidates
Feb 24, 2015 - 1:00 p.m.
Medical Center Ryan Case Method Room (1-9576)

Student Seminar (BCH 502/BPH 572) for Mallory Scott and Matthew Payea

Mallory Scott & Matthew Payea - PhD Candidates
Feb 24, 2015 - 1:00 p.m.
Medical Center Ryan Case Method Room (1-9576)

Structural Mechanisms of Sensing dsRNA Via Regulated RNA Decay in Human Cells

Alexei Korennykh, Ph.D. - Assistant Professor, Department of Molecular Biology, Princeton University, Princeton, NJ
Feb 25, 2015 - 2:00 p.m.
Medical Center K-307 (3-6408)
Host: Drs. Dmitri Ermolenko & Lynne Maquat

Student Seminar (BCH 502/BPH 572) for Owen Smith and Karl Smith

Owen Smith & Karl Smith - PhD Candidates
Mar 03, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Owen Smith and Karl Smith

Owen Smith & Karl Smith - PhD Candidates
Mar 03, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Tumor Clonal Heterogeneity: Implications for Biology and Disease

Matthew Walter, M.D., Ph.D. - Associate Professor, Departments of Medicine and Genetics, Washington University School of Medicine, St. Louis, MO
Mar 04, 2015 - 12:00 p.m.
Medical Center Class of '62 Auditorium (G-9425)
Host: Drs. Clara Kielkopf & Richard Burack

Student Seminar (BCH 502/BPH 572) for Amber Cutter and Michael Sloma

Amber Cutter & Michael Sloma - PhD Candidates
Mar 10, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Amber Cutter and Michael Sloma

Amber Cutter & Michael Sloma - PhD Candidates
Mar 10, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Antibiotic Resistance: Evolutionary Tales from the Protein Data Bank

Stephen Burley, M.D., D.Phil. - Director, RCSB Protein Data Bank; Director, Center for Integrative Proteomics Research; Member, Rutgers Cancer Institute of New Jersey; Distinguished Professor of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, New Brunswick, NJ
Mar 11, 2015 - 2:00 p.m.
Medical Center K-307 (3-6408)
Host: Dr. Joseph Wedekind

Student Seminar (BCH 502/BPH 572) for Kyle Berger and Bronwyn Lucas

Kyle Berger & Bronwyn Lucas - PhD Candidates
Mar 17, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Kyle Berger and Bronwyn Lucas

Kyle Berger & Bronwyn Lucas - PhD Candidates
Mar 17, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Mechanisms to Regulate Gene Expression by Disrupting Protein Synthesis

Christine Dunham, Ph.D. - Assistant Professor, Department of Biochemistry, Emory University School of Medicine
Mar 18, 2015 - 2:00 p.m.
Medical Center 3-6408 (K-307)
Host: Dr. Dmitri Ermolenko

Student Seminar (BCH 502/BPH 572) for Lu Han and Sierra Fox

Lu Han & Sierra Fox - PhD Candidates
Mar 24, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Lu Han and Sierra Fox

Lu Han & Sierra Fox - PhD Candidates
Mar 24, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Molecular Cooperation in Gene Regulation and Genomic Stability

Evgeny Nudler, Ph.D. - Howard Hughes Medical Institute Investigator; Julie Wilson Anderson Professor, Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY
Mar 25, 2015 - 2:00 p.m.
Medical Center K-307 (3-6408)
Host: Dr. Dmitri Ermolenko

Student Seminar (BCH 502/BPH 572) for Shairy Danial and Christopher Goodwin

Shairy Danial & Christopher Goodwin - PhD Candidates
Mar 31, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Shairy Danial and Christopher Goodwin

Shairy Danial & Christopher Goodwin - PhD Candidates
Mar 31, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Monitoring Translation in Space and Time with Ribosome Profiling

Jonathan Weissman, Ph.D. - Professor, Howard Hughes Medical Institute, Department of Cellular & Molecular Pharmacology, University of California, San Francisco
Apr 01, 2015 - 1:00 p.m.
Medical Center Class of '62 Auditorium (G-9425)
Host: Drs. Sina Ghaemmaghami & Lynne Maquat

Student Seminar (BCH 502/BPH 572) for Steven Henderson and Debapratim Dutta

Steven Henderson & Debapratim Dutta - PhD Candidate
Apr 07, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Steven Henderson and Debapratim Dutta

Steven Henderson & Debapratim Dutta - PhD Candidate
Apr 07, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Peptides and Proteins in Lipid Bilayers

Régis Pomès, Ph.D. - Senior Scientist, Molecular Structure and Function, Hospital for Sick Children; Associate Professor, Department of Biochemistry, University of Toronto
Apr 08, 2015 - 2:00 p.m.
Medical Center K-307 (3-6408)
Host: Dr. Alan Grossfield

Student Seminar (BCH 502/BPH 572) for Mohammad Kayedkhordeh and Lingfeng Luo

Mohammad Kayedkhordeh & Lingfeng Luo - PhD Candidates
Apr 14, 2015 - 1:00 p.m.
Medical Center 1-7619 (Adolph Auditorium)

Student Seminar (BCH 502/BPH 572) for Mohammad Kayedkhordeh and Lingfeng Luo

Mohammad Kayedkhordeh & Lingfeng Luo - PhD Candidates
Apr 14, 2015 - 1:00 p.m.
Medical Center 1-7619 (Adolph Auditorium)

Mouse Models for Studying APOBEC3-mediated Restriction of Virus Infection

Susan Ross, Ph.D. - Interim Chair & Professor, Department of Microbiology, Perelman School of Medicine University of Pennsylvania
Apr 15, 2015 - 2:00 p.m.
Medical Center 3-6408 (K-307)
Host: Drs. Harold Smith & Stephen Dewhurst

Student Seminar (BCH 502/BPH 572) for Jiyu Wang and Leslie Salas Estrada

Jiyu Wand & Leslie Salas Estrada - PhD Candidates
Apr 21, 2015 - 1:00 p.m.
Medical Center 1-7619 (Adolph Auditorium)

Student Seminar (BCH 502/BPH 572) for Jiyu Wang and Leslie Salas Estrada

Jiyu Wand & Leslie Salas Estrada - PhD Candidates
Apr 21, 2015 - 1:00 p.m.
Medical Center 1-7619 (Adolph Auditorium)

Student Seminar (BCH 502/BPH 572) for Zhen Tan and Hong Zhu

Zhen Tan & Hong Zhu - PhD Candidates
Apr 28, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Student Seminar (BCH 502/BPH 572) for Zhen Tan and Hong Zhu

Zhen Tan & Hong Zhu - PhD Candidates
Apr 28, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

How RNA Structures 'Jiggle and Wiggle' at Atomic Resolution: Importance to Function and Drug Discovery

Hashim M. Al-Hashimi, Ph.D. - Director, Duke Center for RNA Biology; Professor, Departments of Biochemistry and Chemistry, Duke University School of Medicine, Durham, NC
Apr 29, 2015 - 2:00 p.m.
Medical Center K-307 (3-6408)
Host: Dr. Benjamin Miller

Towards RNA Structure/Function from Scratch

Rhiju Das, Ph.D. - Assistant Professor, Departments of Biochemistry and Physics, Stanford University, Stanford, CA
May 06, 2015 - 2:00 p.m.
Medical Center K-307 (3-6408)
Host: T32 Training Grant Graduate Students (Michael Sloma)

Regulation of MicroRNA Biogenesis and Function

Javier F. Cáceres, Ph.D. - MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Scotland
May 20, 2015 - 2:00 p.m.
Medical Center K-307 (3-6408)
Host: Dr. Lynne Maquat

Automating Comparative Sequence Analysis for RNA Secondary Structure Prediction: An Iterative Probabilistic "Turbo Decoding" Framework

Dr. Gaurav Sharma - Professor, Department of Electrical and Computer Engineering
Jun 10, 2015 - 2:00 p.m.
Medical Center 3-6408 (K-307)

Inference of Systems-level Responses to Influenza Infections

Dr. Juliee Thakar - Assistant Professor, Department of Microbiology and Immunology & Biostatistics and Computational Biology
Jun 17, 2015 - 2:00 p.m.
Medical Center 3-6408 (K-307)

Nucleosome Linker DNA Directed Folding of the Linker Histone C-Terminal Domain

He Fang - PhD Candidate
Sep 29, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

The impact of oncogenic signaling on metabolic stress responses and human cytomegalovirus infection

Shihao Xu - PhD Candidate
Oct 06, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

TBD

Thomas Hilimire - PhD Candidate
Oct 27, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

TBD

Rakesh Chatrikhi - PhD Candidate
Nov 03, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Translational control by initiation factor 2 and the class II preQ1 riboswitch

Clarence Ling - PhD Candidate
Nov 10, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Pairs of adjacent codons inhibit translation by different mechanisms

Christina Brule - PhD Candidate
Nov 17, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Regulation of membrane localization of type two voltage gated calcium channels

Mallory Scott - PhD Candidate
Nov 24, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Using a Log Linear Model to Study the Influence of Evolutionary Constraints on RNA Secondary Structures and Alignments

Yinghan Fu - PhD Candidate
Dec 01, 2015 - 1:00 p.m.
Medical Center 3-7619

The Science of Ultrathin Membrane Separations

Karl Smith - PhD Candidate
Dec 08, 2015 - 1:00 p.m.
Medical Center 3-7619

Mitochondrial Slick Potassium Channels And Heart Mitochondrial Function

Charles Smith - PhD Candidate
Dec 15, 2015 - 1:00 p.m.
Medical Center 3-7619 (Upper S-Wing Auditorium)

Event Photos