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Aging Bioinformatics Cancer Biology Cardiovascular System Cell Signaling CNS Development Disease Models Metabolics Musculoskeletal System Pulmonary Stem Cells Translational Research

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Affiliated Faculty

Kate Ackerman, M.D.
Kate Ackerman, M.D.

Ackerman Lab

Pediatrics
Biomedical Genetics
Research Interest: Genetics of Congenital Diaphragmatic Hernia in lung development

Not accepting students at this time.
Brian Altman, Ph.D.
Brian Altman, Ph.D.

Altman Lab

Biomedical Genetics
Research Interest: Role of Circadian Rhythm in in gene regulation and cancer cell biology and metabolism.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Jeevisha Bajaj, Ph.D.
Jeevisha Bajaj, Ph.D.

Bajaj Lab

Biomedical Genetics
Research Interest: Molecular mechanisms of cancer stem cell interactions with tumor microenvironment in disease progression

Mentor for Genetics, Development, and Stem Cells Ph.D. Program & Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Danielle Benoit, Ph.D.
Danielle Benoit, Ph.D.

Benoit Lab

Chemical Engineering
Biomedical Engineering
Research Interest: Therapeutic biomaterials development for tissue engineering and drug delivery with applications ranging from bone regeneration to antioral biofilm treatments

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Daniel Bergstralh, Ph.D.
Daniel Bergstralh, Ph.D.

Bergstralh Lab

Biology
Biomedical Genetics
Research Interest: Investigating cell division and adhesion in epithelial tissues, with a particular interest in how tissue integrity is established and maintained during development.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Bradford Berk, M.D., Ph.D.
Bradford Berk, M.D., Ph.D.

Berk Lab

Medicine
Pharmacology & Physiology
Research Interest: Signaling transduction mechanisms in the vascular system

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Xin Bi, Ph.D.
Xin Bi, Ph.D.

Bi Lab

Biology
Research Interest: Chromatin-mediated regulation of gene expression in eukaryotes.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Benoit Biteau, Ph.D.
Benoit Biteau, Ph.D.

Biteau Lab

Biomedical Genetics
Research Interest: Molecular and Cellular Mechanisms that Control Tissue Homeostasis and Somatic Stem Cells

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Dirk Bohmann, Ph.D.
Dirk Bohmann, Ph.D.

Bohmann Lab

Biomedical Genetics
Research Interest: The biochemistry, molecular biology and genetics of signal-transducing transcription factors and their role in development, aging and disease

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Paul Boutz, Ph.D.
Paul Boutz, Ph.D.

Boutz Lab

Biochemistry & Biophysics
Research Interest: Regulation of pre-mRNA splicing and polyadenylation in healthy and diseased states; the contribution of RNA processing to cancer biology; effects of small molecule drugs on RNA processing and gene expression.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Michael Bulger, Ph.D.
Michael Bulger, Ph.D.

Bulger Lab

Pediatrics
Biochemistry & Biophysics
Research Interest: Chromatin domains and long-range activation by enhancers

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Joe Chakkalakal, Ph.D.
Joe Chakkalakal, Ph.D.

Chakkalakal Lab

Pharmacology & Physiology
Research Interest: Contribution of stem cells to the maturation, regeneration and lifelong maintenance of skeletal muscle in growth aging and cancer

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Stephen Dewhurst, Ph.D.
Stephen Dewhurst, Ph.D.

Dewhurst Lab

UofR Cell Therapy Manufacturing Facility (UofR - CTMF)

Microbiology & Immunology
Research Interest: Influenza Viruses; Virus Polymerase HIV Vaccine Development; NeuroAIDS Research

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Mark Dumont, Ph.D.
Mark Dumont, Ph.D.

Dumont Lab

Biochemistry & Biophysics
Pediatrics
Research Interest: Signal transduction; membrane protein structure, yeast molecular biology

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Thomas Eickbush, Ph.D.
Thomas Eickbush, Ph.D.

Eickbush Lab

Biology
Research Interest: Retrotransposable elements, protein: RNA and protein: DNA interactions, sequence specific endonucleases.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Dmitri Ermolenko, Ph.D.
Dmitri Ermolenko, Ph.D.

Ermolenko Lab

Biochemistry & Biophysics
Biology
Research Interest: Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Robert Freeman, Ph.D.
Robert Freeman, Ph.D.

Freeman Lab

Pharmacology & Physiology
Research Interest: Molecular biology of programmed cell death

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
James Fry, Ph.D.
James Fry, Ph.D.

Fry Lab

Biology
Research Interest: Identifying the genetic changes underlying the temperate-tropical difference

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Elizabeth Grayhack, Ph.D.
Elizabeth Grayhack, Ph.D.

Grayhack Lab

Biochemistry & Biophysics
Research Interest: Role of the genetic code in regulating protein synthesis and mRNA metabolism in Saccharomyces cerevisiae.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Isaac Harris, Ph.D.
Isaac Harris, Ph.D.

Harris Lab

Biomedical Genetics
Research Interest: Understanding the roles of antioxidants in cancer

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Jeffrey Hayes, Ph.D.
Jeffrey Hayes, Ph.D.

William A. Bernhard Memorial Lab

Hayes Lab

Biochemistry & Biophysics
Biochemistry & Biophysics
Research Interest: Regulation of transcription, nuclear processes, related to chromatin structure and function

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Aram Hezel, M.D.
Aram Hezel, M.D.
Medicine
Biomedical Genetics
Research Interest: The molecular biology and genetics of pancreatic and biliary tract cancers

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Wei Hsu, PhD
Wei Hsu, PhD

Hsu Lab

Biomedical Genetics
Research Interest: Cellular Signaling in Neural Development and Disease

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Amy Kiernan, Ph.D.
Amy Kiernan, Ph.D.

Kiernan Lab

Ophthalmology
Biomedical Genetics
Flaum Eye Institute
Research Interest: Molecular development of the eye and inner ear; anterior segment dysgenesis (ASD) and developmental glaucoma; congenital deafness and vestibular dysfunction

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Hartmut Land, Ph.D.
Hartmut Land, Ph.D.

Land Lab

Biomedical Genetics
Biomedical Genetics
Biochemistry & Biophysics
Research Interest: Molecular mechanisms of carcinogenesis. Signaling and Cancer Cell Metabolism

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Amanda Larracuente, Ph.D.
Amanda Larracuente, Ph.D.

Larracuente Lab

Biology
Research Interest: Satellite DNA (repetitive DNA typically found at centromeres and telomeres), Meiotic Drive, and Selfish DNA using genomic, population genetic, molecular and cytological methods.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Xin Li, Ph.D.
Xin Li, Ph.D.

Li Lab

Biochemistry & Biophysics
Research Interest: Epigenetic inheritance, small silencing non-coding RNAs, translational control, lead toxicity, and comparative genomics.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Richard Libby, Ph.D.
Richard Libby, Ph.D.

Libby Lab

Biomedical Genetics
Ophthalmology
Flaum Eye Institute
Research Interest: Neurobiology of glaucoma, molecular processes that lead to retinal ganglion cell death.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Alayna Loiselle, Ph.D.
Alayna Loiselle, Ph.D.

Loiselle Lab

Orthopaedics
Research Interest: Identify novel strategies to improve flexor tendon healing

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Lynne Maquat, Ph.D.
Lynne Maquat, Ph.D.

Maquat Lab

Biochemistry & Biophysics
Research Interest: RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Thomas Mariani, Ph.D.
Thomas Mariani, Ph.D.

Mariani Lab

Pediatrics
Environmental Medicine
Medicine
Biomedical Genetics
Research Interest: Genetic mechanisms of susceptibility to chronic lung diseases, focusing on developmental antecedents and influence of environmental factors.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
David Mathews, M.D., Ph.D.
David Mathews, M.D., Ph.D.

Mathews Lab

Biochemistry & Biophysics
Research Interest: Computational biology of RNA, including structure prediction, molecular dynamics, and genomics.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Margot Mayer-Pröschel, Ph.D.
Margot Mayer-Pröschel, Ph.D.

Mayer-Pröschel Lab

Biomedical Genetics
Neuroscience
Research Interest: Identification of different stem and precursor cell pools in CNS that may be critical for cell replacement therapies or are targets of insults that lead to developmental pathologies.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Matthew McCall, Ph.D.
Matthew McCall, Ph.D.
Biomedical Genetics
Biostatistics & Computational Biology
Research Interest: Developing methods to estimate gene regulatory networks from gene perturbation experiments

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Helene McMurray, Ph.D.
Helene McMurray, Ph.D.

McMurray Lab

Pathology & Laboratory Medicine
Research Interest: Analysis of gene regulatory networks in cancer; role of immunogenetics in transplant

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Stephano Mello, Ph.D.
Stephano Mello, Ph.D.

Mello Lab

Biomedical Genetics
Research Interest: Understanding how nuclear proteins and non-coding RNAs (ncRNAs) regulate gene transcription in pancreatic preneoplastic lesions, gaining knowledge of the process of cellular transformation and tumor initiation.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Edward Messing, M.D.
Edward Messing, M.D.
Urology
Pathology & Laboratory Medicine
Urology
Research Interest: Prostate and Bladder cancer

Not accepting students at this time.
Patrick Murphy, Ph.D.
Patrick Murphy, Ph.D.

Patrick Murphy Lab

Biomedical Genetics
Research Interest: The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Keith Nehrke, Ph.D.
Keith Nehrke, Ph.D.

Nehrke Lab

Medicine
Pharmacology & Physiology
Research Interest: Integrative Physiology

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Mark Noble, Ph.D.
Mark Noble, Ph.D.

Noble Lab

Biomedical Genetics
Neuroscience
Research Interest: Neuro stem cell biology and medicine, developing pharmacological and cell based approaches to peripheral and spinal cord injury.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Mitchell O'Connell, Ph.D.
Mitchell O'Connell, Ph.D.

O'Connell Lab

Biochemistry & Biophysics
Research Interest: Biochemical mechanisms of RNA-mediated gene regulation; RNA-targeting CRISPR tool development

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Michael O'Reilly, Ph.D.
Michael O'Reilly, Ph.D.

O'Reilly Lab

Environmental Medicine
Pediatrics
Research Interest: Understanding how an aberrant oxygen environment at birth disrupts development of the lung and heart, leading to persistent functional changes over the lifespan.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Catherine Ovitt, Ph.D.
Catherine Ovitt, Ph.D.

Ovitt Lab

Biomedical Genetics
Research Interest: Protective and regenerative strategies for salivary gland function and radiation therapies.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Alexander Paciorkowski, M.D.
Alexander Paciorkowski, M.D.

Paciorkowski Lab

Neurology
Biomedical Genetics
Neuroscience
Research Interest: Pediatric Neurology, Human Genetics

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
James Palis, M.D.
James Palis, M.D.

Palis Lab

Pediatrics
Biomedical Genetics
Research Interest: Cellular and Molecular events underlying the ontogeny of the hematopoietic system.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Archibald Perkins, M.D., Ph.D.
Archibald Perkins, M.D., Ph.D.

Perkins / Zhang Lab

Pathology & Laboratory Medicine
Research Interest: Genetic mechanisms in acute myeloid leukemia and myelodysplastic syndrome with focus on the zinc finger oncoprotein EVI1

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Eric Phizicky, Ph.D.
Eric Phizicky, Ph.D.

Phizicky Lab

Biochemistry & Biophysics
Research Interest: tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Douglas Portman, Ph.D.
Douglas Portman, Ph.D.

Portman Lab

Biomedical Genetics
Neuroscience
Research Interest: Neural circuit development and function; Genetic control of behavior; Sex differences in neurobiology

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Christoph Pröschel, Ph.D.
Christoph Pröschel, Ph.D.

Pröschel Lab

Biomedical Genetics
Research Interest: Glial progenitor cells and role of astrocytes as critical modulators in CNS disease and repair

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Jacques Robert, Ph.D.
Jacques Robert, Ph.D.

Robert Lab

Microbiology & Immunology
Environmental Medicine
Research Interest: Experimental platform using the amphibian Xenopus for research in immunotoxicology, fundamental and medical immunology

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Andrew Samuelson, Ph.D.
Andrew Samuelson, Ph.D.

Samuelson Lab

Biomedical Genetics
Research Interest: Understanding the genetic, cell biological and molecular basis for age-driven proteostatic deterioration

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Edward Schwarz, Ph.D.
Edward Schwarz, Ph.D.

Schwarz Lab

Orthopaedics
Microbiology & Immunology
Biomedical Engineering
Medicine
Pathology & Laboratory Medicine
Urology
Research Interest: Inflammatory bone loss as seen in rheumatoid arthritis, infections, tumor metastasis and wear debris induced osteolysis around prosthetic implants

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Ruchira Singh, Ph.D.
Ruchira Singh, Ph.D.

Singh Lab

Ophthalmology
Biomedical Genetics
Flaum Eye Institute
Research Interest: Using patient-derived human induced pluripotent stem cells (hiPSCs) to study the molecular mechanism of specific retinal and neurological diseases and applying that knowledge to pharmacologically target certain retinal disorders in patient-derived cells.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Laurie Steiner, M.D.
Laurie Steiner, M.D.

Steiner Lab

Pediatrics
Medicine
Research Interest: Utilizes genomics techniques to study the molecular mechanisms underlying erythroid maturation and development in both normal and disease states

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Juilee Thakar, Ph.D.
Juilee Thakar, Ph.D.

Thakar Lab

Microbiology & Immunology
Research Interest: Systems approach utilizing bioinformatics, and dynamic modeling tools to study immune response to infections and vaccination.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Charles Thornton, M.D.
Charles Thornton, M.D.

Thornton Lab

Neurology
Research Interest: Myotonic dystrophy, repeat expansion diseases, and therapeutic development for neuromuscular disorders.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Paula Vertino, Ph.D.
Paula Vertino, Ph.D.

Vertino Lab

Biomedical Genetics
Research Interest: Cancer epigenetics: the role of DNA methylation and chromatin in driving cancer phenotypes and as a target for therapeutic intervention

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Michael Welte, Ph.D.
Michael Welte, Ph.D.

Welte Lab

Biology
Research Interest: How microtubule motors, such as kinesins and dyneins, transport organelles and other cargoes throughout the cell.

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Jack Werren, Ph.D.
Jack Werren, Ph.D.
Biology
Research Interest: Evolutionary Genetics

Mentor for Genetics, Development, and Stem Cells Ph.D. Program
Jiyong Zhao, Ph.D.
Jiyong Zhao, Ph.D.

Land Lab

Zhao Lab

Biomedical Genetics
Research Interest: Signal transduction and development of therapeutic agents in B-lymphomas; Cell cycle regulation

Mentor for Genetics, Development, and Stem Cells Ph.D. Program