Kate G. Ackerman, M.D.
|Congenital Diaphragmatic Hernia|
Cheryl Ackert-Bicknell, Ph.D.
Danielle Benoit, Ph.D.
Benoit LabBiomedical Engineering
|Investigating cell division and adhesion in epithelial tissues, with a particular interest in how tissue integrity is established and maintained during development.|
Bradford C. Berk, M.D., Ph.D.
|Signal transduction mechanisms in the vasculature|
Xin Bi, Ph.D.
|Chromatin-mediated regulation of gene expression in eukaryotes.|
Benoit Biteau, Ph.D.
Biteau LabBiomedical Genetics
|Molecular and Cellular Mechanisms that Control Tissue Homeostasis and Somatic Stem Cells|
Dirk Bohmann, Ph.D.
Bohmann LabBiomedical Genetics
|The biochemistry, molecular biology and genetics of signal-transducing transcription factors and their role in development, aging and disease|
Michael D. Bulger, Ph.D.
|Chromatin domains and long-range activation by enhancers|
Joe V. Chakkalakal, Ph.D.
|Satellite cells are a population of resident stem cells that serve as a renewable source of progenitors for the growth and regeneration of skeletal muscle.|
Stephen Dewhurst, Ph.D.
Dewhurst LabMicrobiology & Immunology
|Influenza Viruses; Virus Polymerase HIV Vaccine Development; NeuroAIDS Research|
Mark E. Dumont, Ph.D.
Dumont LabBiochemistry & Biophysics
|Signal transduction; membrane protein structure, yeast molecular biology|
Thomas Eickbush, Ph.D.
|Retrotransposable elements, protein: RNA and protein: DNA interactions, sequence specific endonucleases.|
Dmitri N. Ermolenko, Ph.D.
Ermolenko LabBiochemistry & Biophysics
|Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.|
Robert S. Freeman, Ph.D.
Freeman LabPharmacology & Physiology
|Molecular biology of programmed cell death|
James D. Fry, Ph.D.
|Identifying the genetic changes underlying the temperate-tropical difference|
Lin Gan, Ph.D.
|Development and degenerative diseases of sensory neurons, gene regulation|
David S. Goldfarb, Ph.D.
|Molecular mechanisms that control the exchange of molecules and information between the nucleus and cytoplasm|
Elizabeth Grayhack, Ph.D.
Grayhack LabBiochemistry & Biophysics
|Role of the genetic code in regulating protein synthesis and mRNA metabolism in <em>Saccharomyces cerevisiae</em>.|
Jeffrey J. Hayes, Ph.D.
William A. Bernhard Memorial Lab
Hayes LabBiochemistry & Biophysics
|DNA structure; chromatin; protein-DNA interactions|
Aram Francis Hezel, M.D.
|Medicine||The molecular biology and genetics of pancreatic and biliary tract cancers |
Wei Hsu, PhD
Hsu LabBiomedical Genetics
|Cellular Signaling in Neural Development and Disease|
Amy Kiernan, Ph.D.
|Molecular development of the inner ear; regeneration; congenital deafness and vestibular dysfunction|
Vyacheslav A. Korshunov, Ph.D.
Catherine K. Kuo, Ph.D.
Kuo LabBiomedical Engineering
|Adult stem cell biology; Tissue engineering and regenerative medicine; Embryonic tendon development; Scarless wound healing|
Hartmut Land, Ph.D.
Land LabBiomedical Genetics
|Molecular mechanisms of carcinogenesis. Signaling and Cancer Cell Metabolism|
Xin Zhiguo Li, Ph.D.
Li LabBiochemistry & Biophysics
|Small non-coding RNA regulation in germ cells; paternal aging; transgenerational inheritance.|
Richard Libby, Ph.D.
|Neurobiology of glaucoma; specifically the death of retinal ganglion cells (RGCs), the output neurons of the retina.|
Sanjay Maggirwar, Ph.D.
Maggirwar LabMicrobiology & Immunology
|Platelets, HIV, and inflammation|
Lynne Maquat, Ph.D.
Maquat LabBiochemistry & Biophysics
|RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases. |
Thomas Mariani, Ph.D.
|Systems Biology of Lung Development and Disease|
David H. Mathews, M.D., Ph.D.
Mathews LabBiochemistry & Biophysics
|Computational biology of RNA, including structure prediction, molecular dynamics, and genomics.|
Margot Mayer-Pröschel, Ph.D.
Mayer-Pröschel LabBiomedical Genetics
|Stem Cells in the mammalian CNS / Gestational insults and embryonic CNS development / Astrocyte dysfunction|
Helene R. McMurray, Ph.D.
McMurray LabBiomedical Genetics
|Systems Biology of Cancer Cells|
Joseph M. Miano, Ph.D.
|Discovery and function of long noncoding RNAs and CArG regulatory elements in mouse and human genomes; genome editing in mice|
Keith Webster Nehrke, Ph.D.
Mark Noble, Ph.D.
Noble LabBiomedical Genetics
|Neural Diseases and Neoplasia|
Michael A. O'Reilly, Ph.D.
|Developmental Biology of the Lung|
Catherine E. Ovitt, Ph.D.
Ovitt LabBiomedical Genetics
|Analysis of Genes Involved in Salivary Gland Function|
Alexander R. Paciorkowski, M.D.
|Pediatric Neurology, Human Genetics|
James Palis, M.D.
|Pediatric Hematology and Oncolog|
Archibald S. Perkins, M.D., Ph.D.
Perkins LabPathology & Laboratory Medicine
|Genes that impact the development of leukemias and other human malignancies|
Eric Phizicky, Ph.D.
Phizicky LabBiochemistry & Biophysics
|tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.|
Douglas Portman, Ph.D.
Portman LabBiomedical Genetics
|Neural circuit development and function; Genetic control of behavior; Sex differences in neurobiology|
Christoph Pröschel, Ph.D.
Pröschel LabBiomedical Genetics
|Glial progenitors and the role of astrocytes in CNS disease and repair.|
Jacques Robert, Ph.D.
Robert LabMicrobiology & Immunology
|Evolution of Immune Surveillance, Tumor and Viral Immunity|
Andrew V. Samuelson, Ph.D.
Samuelson LabBiomedical Genetics
|Understanding Aging at the Genetic, Molecular, Cellular, and Organismal Level|
Edward M. Schwarz, Ph.D.
|Pro-inflammatory cytokine signal transduction and novel drug and gene therapies for Rheumatoid Arthritis.|
Ruchira Singh, Ph.D.
|Cellular and molecular mechanisms of retinal and neurodegenerative diseases in patient-derived induced pluripotent stem cell (iPSC) model systems|
Harold C. Smith, Ph.D.
Smith LabBiochemistry & Biophysics
|RNA regulation of innate immune modulators and small molecule inhibitors of HIV RNA-binding proteins.|
Laurie A. Steiner, M.D.
|Pediatric Biomedical Research|
Juilee Thakar, Ph.D.
Thakar LabMicrobiology & Immunology
|Identification of immune signatures and characterization of dynamics of immune responses by using systems biology approaches.|
Charles A. Thornton, M.D.
|Neurogenetic disorders, including myotonic dystrophy; therapeutics, including antisense approaches.|
Michael A. Welte, Ph.D.
|How microtubule motors, such as kinesins and dyneins, transport organelles and other cargoes throughout the cell.|
Jack Werren, Ph.D.
Lei Xu, Ph.D.
Xu LabBiomedical Genetics
|GPR56 in Cancer|
Jiyong Zhao, Ph.D.
Zhao LabBiomedical Genetics
|Signal transduction and development of therapeutic agents in B-lymphomas; Cell cycle regulation|