Kate G. Ackerman, M.D.
|Congenital Diaphragmatic Hernia|
Cheryl Ackert-Bicknell, Ph.D.
Danielle Benoit, Ph.D.
Benoit LabBiomedical Engineering
|Research projects are at the interface of medicine and engineering, with an emphasis on precisely controlling biomaterial functionality and architecture to treat diseases, control cell behavior, or answer fundamental biological questions.|
|Investigating cell division and adhesion in epithelial tissues, with a particular interest in how tissue integrity is established and maintained during development.|
Bradford C. Berk, M.D., Ph.D.
|Signal transduction mechanisms in the vasculature|
Xin Bi, Ph.D.
|Chromatin-mediated regulation of gene expression in eukaryotes.|
Benoit Biteau, Ph.D.
Biteau LabBiomedical Genetics
|Molecular and Cellular Mechanisms that Control Tissue Homeostasis and Somatic Stem Cells|
Dirk Bohmann, Ph.D.
Bohmann LabBiomedical Genetics
|The biochemistry, molecular biology and genetics of signal-transducing transcription factors and their role in development, aging and disease|
Michael D. Bulger, Ph.D.
|Chromatin domains and long-range activation by enhancers|
Joe V. Chakkalakal, Ph.D.
|Satellite cells are a population of resident stem cells that serve as a renewable source of progenitors for the growth and regeneration of skeletal muscle.|
Stephen Dewhurst, Ph.D.
Dewhurst LabMicrobiology & Immunology
|Influenza Viruses; Virus Polymerase HIV Vaccine Development; NeuroAIDS Research|
Mark E. Dumont, Ph.D.
Dumont LabBiochemistry & Biophysics
|Signal transduction; membrane protein structure, yeast molecular biology|
Thomas Eickbush, Ph.D.
|Retrotransposable elements, protein: RNA and protein: DNA interactions, sequence specific endonucleases.|
Dmitri N. Ermolenko, Ph.D.
Ermolenko LabBiochemistry & Biophysics
|Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.|
Robert S. Freeman, Ph.D.
Freeman LabPharmacology & Physiology
|Molecular biology of programmed cell death|
James D. Fry, Ph.D.
|Identifying the genetic changes underlying the temperate-tropical difference|
Lin Gan, Ph.D.
|Development and degenerative diseases of sensory neurons, gene regulation|
David S. Goldfarb, Ph.D.
|Molecular mechanisms that control the exchange of molecules and information between the nucleus and cytoplasm|
Elizabeth Grayhack, Ph.D.
Grayhack LabBiochemistry & Biophysics
|Role of the genetic code in regulating protein synthesis and mRNA metabolism in <em>Saccharomyces cerevisiae</em>.|
Jeffrey J. Hayes, Ph.D.
William A. Bernhard Memorial Lab
Hayes LabBiochemistry & Biophysics
|DNA structure; chromatin; protein-DNA interactions|
Aram Francis Hezel, M.D.
|Medicine||The molecular biology and genetics of pancreatic and biliary tract cancers |
Wei Hsu, PhD
Hsu LabBiomedical Genetics
|Cellular Signaling in Neural Development and Disease|
Amy Kiernan, Ph.D.
|Molecular development of the inner ear; regeneration; congenital deafness and vestibular dysfunction|
Vyacheslav A. Korshunov, Ph.D.
Catherine K. Kuo, Ph.D.
Kuo LabBiomedical Engineering
|Adult stem cell biology; Tissue engineering and regenerative medicine; Embryonic tendon development; Scarless wound healing|
Hartmut Land, Ph.D.
Land LabBiomedical Genetics
|Molecular mechanisms of carcinogenesis. Signaling and Cancer Cell Metabolism|
Xin Zhiguo Li, Ph.D.
Li LabBiochemistry & Biophysics
|Small non-coding RNA regulation in germ cells; paternal aging; transgenerational inheritance.|
Richard Libby, Ph.D.
|Neurobiology of glaucoma; specifically the death of retinal ganglion cells (RGCs), the output neurons of the retina.|
Alayna E. Loiselle, Ph.D.
|cellular and molecular mechanisms of musculoskeletal tissue regeneration and pathology|
Sanjay Maggirwar, Ph.D.
Maggirwar LabMicrobiology & Immunology
|Platelets, HIV, and inflammation|
Lynne Maquat, Ph.D.
Maquat LabBiochemistry & Biophysics
|RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases. |
Thomas Mariani, Ph.D.
|Systems Biology of Lung Development and Disease|
David H. Mathews, M.D., Ph.D.
Mathews LabBiochemistry & Biophysics
|Computational biology of RNA, including structure prediction, molecular dynamics, and genomics.|
Margot Mayer-Pröschel, Ph.D.
Mayer-Pröschel LabBiomedical Genetics
|Stem Cells in the mammalian CNS / Gestational insults and embryonic CNS development / Astrocyte dysfunction|
Helene R. McMurray, Ph.D.
McMurray LabBiomedical Genetics
|Systems Biology of Cancer Cells|
Joseph M. Miano, Ph.D.
|Discovery and function of long noncoding RNAs and CArG regulatory elements in mouse and human genomes; genome editing in mice|
Keith Webster Nehrke, Ph.D.
Mark Noble, Ph.D.
Noble LabBiomedical Genetics
|Neural Diseases and Neoplasia|
Michael A. O'Reilly, Ph.D.
|Developmental Biology of the Lung|
Catherine E. Ovitt, Ph.D.
Ovitt LabBiomedical Genetics
|Analysis of Genes Involved in Salivary Gland Function|
Alexander R. Paciorkowski, M.D.
|Pediatric Neurology, Human Genetics|
James Palis, M.D.
|Pediatric Hematology and Oncolog|
Archibald S. Perkins, M.D., Ph.D.
Perkins LabPathology & Laboratory Medicine
|Genes that impact the development of leukemias and other human malignancies|
Eric Phizicky, Ph.D.
Phizicky LabBiochemistry & Biophysics
|tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.|
Douglas Portman, Ph.D.
Portman LabBiomedical Genetics
|Neural circuit development and function; Genetic control of behavior; Sex differences in neurobiology|
Christoph Pröschel, Ph.D.
Pröschel LabBiomedical Genetics
|Glial progenitors and the role of astrocytes in CNS disease and repair.|
Jacques Robert, Ph.D.
Robert LabMicrobiology & Immunology
|Evolution of Immune Surveillance, Tumor and Viral Immunity|
Andrew V. Samuelson, Ph.D.
Samuelson LabBiomedical Genetics
|Understanding Aging at the Genetic, Molecular, Cellular, and Organismal Level|
Edward M. Schwarz, Ph.D.
|Novel therapies for musculoskeletal diseases|
Ruchira Singh, Ph.D.
|Cellular and molecular mechanisms of retinal and neurodegenerative diseases in patient-derived induced pluripotent stem cell (iPSC) model systems|
Harold C. Smith, Ph.D.
Smith LabBiochemistry & Biophysics
|RNA regulation of innate immune modulators and small molecule inhibitors of HIV RNA-binding proteins.|
Laurie A. Steiner, M.D.
|Pediatric Biomedical Research|
Juilee Thakar, Ph.D.
Thakar LabMicrobiology & Immunology
|Identification of immune signatures and characterization of dynamics of immune responses by using systems biology approaches.|
Charles A. Thornton, M.D.
|Neurogenetic disorders, including myotonic dystrophy; therapeutics, including antisense approaches.|
Michael A. Welte, Ph.D.
|How microtubule motors, such as kinesins and dyneins, transport organelles and other cargoes throughout the cell.|
Jack Werren, Ph.D.
Lei Xu, Ph.D.
Xu LabBiomedical Genetics
|GPR56 in Cancer|
Jiyong Zhao, Ph.D.
Zhao LabBiomedical Genetics
|Signal transduction and development of therapeutic agents in B-lymphomas; Cell cycle regulation|