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A Closer Look at the Eye: Researchers Develop New Retinal Imaging Technique

Thursday, January 5, 2017

David Williams, Ph.D.

Researchers at the University of Rochester Medical Center have developed a new imaging technique that could revolutionize how eye health and disease are assessed. The group is first to be able to make out individual cells at the back of the eye that are implicated in vision loss in diseases like glaucoma. They hope their new technique could prevent vision loss via earlier diagnosis and treatment for these diseases.

In a study highlighted in the Proceedings of the National Academy of Sciences, Ethan A. Rossi, Ph.D., assistant professor of Ophthalmology at the University of Pittsburgh School of Medicine, describes a new method to non-invasively image the human retina, a layer of cells at the back of the eye that are essential for vision. The group, led by David Williams, Ph.D., Dean for Research in Arts, Sciences, and Engineering and the William G. Allyn Chair for Medical Optics at the University of Rochester, was able to distinguish individual retinal ganglion cells (RGCs), which bear most of the responsibility of relaying visual information to the brain.

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Mother’s Touch May Extend to Brain Development

Thursday, January 5, 2017

child and momA new study sheds light on changes in the brain that may explain why young infants who are placed in an orphanage or foster care often struggle with social relationships later in life.

The findings, which were published in the journal Developmental Psychobiology, come from a team of researchers led by Julie Fudge, M.D., with the University of Rochester Medical Center (URMC) Department of Neuroscience.  The scientists revisited data from a study involving monkeys that took place more than a decade ago at the University of Pittsburgh and was designed to observe the behaviors of newborns that were separated from their biological mothers and raised by another group of females.  The original study noted that these monkeys differed in their social interactions – such as grooming, huddling together, and normal aggression – compared to those that were raised by their mothers.

Like humans, monkey’s brains are not fully developed at birth and the animals are dependent upon the nurturing of caregivers for many months early in life.  Fudge and her colleagues wanted to see if there could find an association between the absence of a primary caregiver and biological changes in the brain that could explain the lasting social impairment observed in the monkeys.

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