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NBA's Patricia White's Research Featured in Journal of Neuroscience

Friday, November 22, 2013

Cochlear Inner Hair Cell

Cochlear inner hair cell from an adult mouse, viewed as a three-dimensional reconstruction from a whole mount confocal stack. The inner hair cell is labeled with Myo7a (grey), ribbon synapses and hair cell nuclei are labeled with CtBP2 (red), and glutamate receptors are labeled with Gria2/3 (green). This technique was used to analyze the role of Foxo3 in the adult mouse cochlea. For more information see Gilels et al..


Assistant Professor of Neurobiology and Anatomy, Patricia White's most recent publication, Mutation of Foxo3 Causes Adult Onset Auditory Neuropathy and Alters Cochlear Synapse Architecture in Mice has been featured in the November edition of the Journal of Neuroscience. In addition, an image of a cochlear inner hair cell from the article was also selected as the cover for that journal.

Dr. White received her bachelor's degree in Biology from the California Institute of Technology in Pasadena in 1989. She completed her Ph.D. degree in Developmental Biology, also at Caltech, in 2000, where she researched neural stem cells. She began post-doctoral work in hearing regeneration at the House Ear Institute, and joined the faculty at the University of Rochester Medical and Dental Center in 2010.

The White lab's goal is to find a biological treatment to reverse noise-induced hearing loss through a better understanding of the function of different genes in the cochlea.

Read More: NBA's Patricia White's Research Featured in Journal of Neuroscience

Professor Laurel Carney Receives NIH-NIDCD Grant Renewal

Thursday, November 21, 2013

Professor Laurel Carney received a renewal for another five years for her NIH-NIDCD grant entitled Auditory Processing of Complex Sounds. The new emphasis for the next five years is to investigate neural coding of speech sounds, starting with vowels. This new direction is possible thanks to the collaboration with Professor Joyce McDonough from the Linguistics Department. This grant will support graduate students and a post-doc in BME, Linguistics, or related fields who are interested in speech coding in the brain.

Clinical Trial for Children with Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)

Friday, November 1, 2013

The University of Rochester Medical Center is currently recruiting subjects with JNCL for a clinical trial. This research study will focus on evaluating whether an investigational drug is safe and well tolerated in children with JNCL. Mycophenolate mofetil (also known as Cellcept) is a medication that suppresses the immune system. The study is 22 weeks long with a total of 8 in-person visits and 4 telephone contacts. Four visits require travel to University of Rochester Medical Center in Rochester, New York, and four visits are with your child’s local physician. Four contacts take place by telephone. Travel costs are covered by the study. Children enrolled in the study will take mycophenolate syrup twice a day, and will have blood drawn at each study visit to monitor safety.

More information on the trial can be found at ClinicalTrials.gov, Time Warner Cable News (Rochester, NY television affiliate) and the URMC Newsroom.

For further information, please contact Amy Vierhile at (585) 275-4762.

Seeing in the Dark

Thursday, October 31, 2013