Faculty A-J Abe, Jun-Ichi , M.D.,University of Yamagata 1987, Ph.D. University of Tokyo 1998 (Professor of Medicine, Aab Cardiovascular Research Institute) Vascular inflammation and atherosclerosis. Ackerman, Kate G. , M.D. SUNY Buffalo 1995 (Associate Professor of Pediatrics, and Biomedical Genetics) Human structural birth defects. Beck, Lisa , M.D. SUNY Stony Brook 1985 (Associate Professor of Dermatology and of Medicine) Characterizing the epithelial tight junction defects at the molecular level in atopic dermatitis. Berk, Bradford, M.D., Ph.D. Rochester 1981 (Professor of Medicine, University of Rochester Medical Center) Molecular biology and genetics of cardiovascular disease. Boyce, Brendan , M.B., Ch.B. Glasgow 1971 (Professor of Pathology and Laboratory Medicine; Director of Anatomic Pathology) Bone cell biology and bone pathology. Brown, Edward B. , Ph.D. Cornell 1999 (Associate Professor of Biomedical Engineering) Tumor biology, using an advanced microscopy technique which allows us to investigate processes inside living tumors. Currently exploring angiogenic signaling in tumor endothelial cells, the structure and function of the tumor extracellular matrix, and the effects of stress on tumor growth. Burack, Richard , M.D., Ph.D. University of Virginia 1995, 1994 (Associate Professor of Pathology and Laboratory Medicine; Director, Hematopathology) Molecular mechanisms of lymphoma progression. Chakkalakal, Joe , Ph.D. University of Ottawa 2006 (Assistant Professor of Orthopaedics, Center for Musculoskeletal Research) Skeletal muscle development, regeneration and neuromuscular disease with a particular emphasis on skeletal muscle stem cell (satellite cell) function and fate. Calvi, Laura , M.D. Harvard 1995 (Associate Professor of Medicine) Microenvironment of hematopoietic stem cells (HSC), especially in osteoblasts (bone-forming cells); stem-cell microenvironmental interactions and pharmacologic strategies. Chang, Chawnshang , Ph.D. Chicago 1985 (George Hoyt Whipple Professor of Pathology and Laboratory Medicine; Professor of Urology and of Radiation Oncology) Molecular mechanisms of steroid hormone function in prostate. Czyzyk, Jan , MD. Medical University of Warsaw 1992 (Assistant Professor of Pathology and Laboratory Medicine) Mechanisms by which anti-serpin activity reduces autoimmune inflammation in the pancreas and developing a protopype of "serpin vaccine" that would enhance anti-serpin immune response. A second lab interest is focused on p21 Ras oncogene and designing a screening method for compounds that block Ras oncogene. Eliseev, Roman , M.D. Russian State Medical University, Moscow, 1995; Ph.D. Rochester 2002 (Assistant Professor, Center for Musculoskeletal Research) The role of bioenergetic mechanisms in regulation of cell fate in mesenchymal stem cells and in cancer cells.. Fay, Philip , Ph.D. Rochester 1982 (Professor of Medicine and of Biochemistry and Biophysics) Human factor VIII structure and function; enzyme co-factor interactions. Gan, Lin , Ph.D. Texas 1992 (Professor of Opthalmology, Director of Research, Flaum Eye Institute; Director, Transgenic and Gene Targeting Core) The role of transcription factors in neural development and diseases. Hammes, Stephen R., M.D., Ph.D. Duke 1992 (Professor of Medicine, Chief, Division of Endocrinology and Metabolism) Steroid synthesis and signaling, focusing on the importance of androgens in mediating prostate cancer growth in men and in regulating normal and pathological ovarian development in women. Hayes, Jeffrey , Ph.D. Johns Hopkins 1990 (Professor of Biochemistry and Biophysics) DNA structure; chromatin; protein-DNA interactions. Hsu, Wei , Ph.D. Mount Sinai, CUNY, 1994 (Associate Professor of Biomedical Genetics in the Center for Oral Biology and Associate Professor of Oncology and Dentistry) Genetic regulatory circuits in development and disease. Jin, Xia , M.D. Peiping Union Medical College, China, 1988; Ph.D. Cambridge University Medical School, UK, 1995 (Associate Professor of Medicine, Infectious Diseases Unit) Immunology of HIV infection and HIV vaccines. Johnson, Gail V.W. , Ph.D. University of Delaware 1984 (Professor of Anesthesiology and of Pharmacology and Physiology) Molecular mechanisms of neurodegeneration; the regulation and function of Transglutaminase 2; tau pathology in Alzheimer's disease; mitochondrial dysfunction in Huntington's disease. Jonason, Jennifer Harrell, Ph.D Yale University 2006 (Assistant Professor of Orthopaedics and Rehabilitation) Signaling mechanisms of skeletal development and disease.