Faculty Q-Z Que, Jianwen , M.D. Beijing University Health Science Center, China, 1999; Ph.D. National University of Singapore, Singapore, 2005 (Assistant Professor of Biomedical Genetics) Morphogenesis of foregut endoderm; stem cell and cancer biology of the esophagus. Rahman, Arshad, Ph.D. AM University Aligarh, India 1988 (Associate Proferssor of Pediatrics and Neonatology) How pro-inflammatory mediators such as thrombin and tumor necrosis factor alpha (THF-a) mediate neutrophils (PMN) sequestration and emigration in the lung and thus induce lung vascular injury. Rothberg, Paul , Ph.D. SUNY Stony Brook 1981 (Professor of Pathology and Laboratory Medicine; Director, Molecular Diagnostics Laboratory) Molecular genetics of cancer and of neurodegeneration. Ryan, Daniel , M.D. Johns Hopkins 1975 (Professor, Pathology and Laboratory Medicine) B-Cell development and differentiation. Schwarz, Edward , Ph.D. Yeshiva, Einstein 1993 (Professor of Orthopaedics and of Microbiology and Immunology) Pro-inflammatory cytokine signal transduction and novel drug and gene therapies for rheumatoid arthritis. Scott, Glynis A. , M.D. Albany 1983 (Professor of Dermatology, Director, Dermatopathology Unit) Signaling pathways of prostaglandins in human melanocytes and melanoma; and the role of Plexin receptors in melanocyte and melanoma biology. Sime, Patricia J. , M.D. University of Edinburgh 1988 (C. Jane Davis & C. Robert Davis Distinguished Professor of Medicine, Division Chief, Pulmonary and Critical Care) Pathogenic mechanisms and novel therapies for lung scarring diseases, therapies for lung inflammation and emphysema incited by cigarette smoke and other inhaled environmental toxicants and resolution pathways in inflammation. Simpson-Haidaris, Patricia J. , Ph.D. Notre Dame 1991 (Associate Professor of Medicine, of Microbiology and Immunology, and of Pathology and Laboratory Medicine) Role of fibrinogen in acute phase response in pneumonitis and fibrinogen gene expression in liver and lung. Singh, Ruchira, Ph.D Kansas State University 2008 (Assistant Professor of Ophthalmology and Biomedical Genetics) Cellular and molecular mechanisms of retinal degenerative diseases in patient-derived induced pluripotent stem cell (iPSC) model systems. Smith, Harold C. , Ph.D. SUNY Buffalo 1982 (Professor of Biochemistry and Biophysics, Pathology, and Toxicology) Diversification of expressed genomic sequences through RNA editing and DNA modification evaluated through biochemical, physiological and structural analysis. Sparks, Janet L. DeHoff , Ph.D. Pennsylvania 1980 (Professor of Pathology and Laboratory Medicine) Insulin regulation of hepatic lipoprotein production through phosphatidylinositide-3-kinase activation via insulin receptor signaling pathways. Wright, Terry W. , Ph.D. Rochester 1995 (Associate Professor of Pediatrics and of Microbiology and Immunology) Host immune response as a major component of lung injury associated with Pneumocystis carinii pneumonia; murine models of this disease; development of improved methods of treatment through targeting the inflammatory and immune pathways involved. Xing, Lianping , M.D, Ph.D. Penn Sate 1994 (Associate Professor of Pathology and Laboratory Medicine) Molecular mechanisms by which TNF mediates the formation, activation and survival of osteoclasts in inflammation induced bone. Yan, Chen , Ph.D. Washington 1996 (Associate Professor of Medicine, Aab Cardiovascular Research Institute Regulation and function of cyclic nucleotide signaling in cardiovascular biology and disease. Yeh, Shu-yuan , Ph.D. Wisconsin, Madison 1996 (Professor of Urology and of Pathology and Laboratory Medicine) Chemopreventive roles of vitamin E in prostate cancer; the cross talk of kinase pathways, androgen receptor and coregulators. Zhang, Xinping , M.D. China-Shanghai Chinese Medical College 1990; Ph.D. Rochester 1998 (Assiociate Professor of Orthopaedics) Molecular and cellular mechanisms of skeletal repair and regeneration. Zuscik, Michael J. , Ph.D. Rochester 1993 (Associate Professor of Orthopaedics) Cellular and molecular processes that govern cartilage development and maturation.