Does this test have other names?
Cardiolipin antibodies (IgG, IgM, IgA), anticardiolipin
What is this test?
A cardiolipin antibodies test looks for a certain kind of antibody in your blood.
The antibodies are IgG (immunoglobulin G), IgA (immunoglobulin A), and IgM (immunoglobulin
M). They are antibodies that form in response to cardiolipins. Cardiolipin is a phospholipid,
or a kind of fat in the blood. The levels of these antibodies are often high in people
with abnormal blood clotting, autoimmune diseases like lupus, or repeated miscarriages.
Why do I need this test?
You may need this test if you often have abnormal blood clotting or abnormal bleeding.
If you have had frequent miscarriages, the test might help healthcare providers figure
out why. Also people with some autoimmune diseases such as lupus have cardiolipin
antibodies in their blood. This test may be used to help diagnose this disease. When
high levels of cardiolipins are found in people with these or other issues, it is
known as cardiolipin antibody syndrome. This test helps diagnose this condition.
What other tests might I have along with this test?
The cardiolipin antibodies test is usually just one of many tests given. The tests
you get will depend on what your healthcare provider is looking for. For example,
if your healthcare provider thinks you have lupus, you will probably need other blood
tests. You will also need imaging tests and tissue biopsies.
These other tests may include:
Complete blood cell count
Partial thromboplastin time and activated prothromboplastin time. These tests see
how your blood clots.
Antinuclear antibody test. These antibodies are found in people with lupus.
Antiphospholipid antibody test. These antibodies are found in people with abnormal
Ultrasound, to look for clots in your arteries or veins
What do my test results mean?
Test results may vary depending on your age, gender, health history, the method used
for the test, and other things. Your test results may not mean you have a problem.
Ask your healthcare provider what your test results mean for you.
The results of a cardiolipin antibodies test are easy to understand. If you're negative
for cardiolipin antibodies, that is normal. If you're positive, you might have cardiolipin
antibody syndrome. You will probably be retested to see if the antibody stays in your
blood. You may need to wait as long as 6 weeks between each test period. This is to
give accurate results for lupus or cardiolipin antibody syndrome.
How is this test done?
The test is done with a blood sample. A needle is used to draw blood from a vein in
your arm or hand.
Does this test pose any risks?
Having a blood test with a needle carries some risks. These include bleeding, infection,
bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may
feel a slight sting or pain. Afterward, the site may be sore.
What might affect my test results?
Although cardiolipin antibodies are commonly related to lupus, a positive test for
them doesn't mean you have lupus. Other tests will be needed to confirm the diagnosis.
When you have problems related to blood clotting, miscarriages, or other issues, this
test result can help healthcare providers figure out the best way to treat your condition.
How do I get ready for this test?
You don't need to prepare for this test.