Diphtheria Antitoxoid Antibody
Does this test have other names?
Anti-diphtheria test, DIPH2, DIPO, DIPE
What is this test?
This test measures the level of diphtheria antibodies in your blood that happen from
being vaccinated against diphtheria or from having a previous diphtheria infection.
Diphtheria is a serious infectious disease caused by C. diphtheriae bacteria. Diphtheria
affects the respiratory tract. It causes symptoms such as:
Diphtheria can be fatal if not treated.
The disease is very rare in the U.S. because most people are vaccinated against it.
The CDC recommends that all children be vaccinated against diphtheria with a vaccine
that also protects against tetanus and whooping cough (pertussis). Because immunity
can fade over time, the CDC also recommends that teens and adults get a booster shot every
Why do I need this test?
You may need this test to find out whether you have or are at risk for diphtheria
if your diphtheria antibodies resulting from the vaccine are too low or have faded
since your last vaccine.
Although the disease is rarely seen in the U.S. and other developed countries, you
may be at risk if:
You are an adult and haven't had a diphtheria booster shot
You recently traveled to a country where diphtheria is common
You recently moved to the U.S. from a country where diphtheria is widespread
What other tests might I have along with this test?
Your healthcare provider may also order a culture test for the diphtheria bacteria.
A positive culture test tells your provider that you have diphtheria.
What do my test results mean?
Test results may vary depending on your age, gender, health history, the method used
for the test, and other things. Your test results may not mean you have a problem.
Ask your healthcare provider what your test results mean for you.
Results are given in international units per milliliter (IU/mL). If you have been
vaccinated against diphtheria, your minimum levels of antibodies should be at least
0.01 to 0.1 IU/mL.
If your test results show a level lower than that, you may be at risk for diphtheria.
If you have certain symptoms, you may need additional tests to find out whether you
actually have diphtheria.
How is this test done?
The test is done with a blood sample. A needle is used to draw blood from a vein in
your arm or hand.
Does this test pose any risks?
Having a blood test with a needle carries some risks. These include bleeding, infection,
bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may
feel a slight sting or pain. Afterward, the site may be sore.
What might affect my test results?
Other factors aren't likely to affect your results.
How do I get ready for this test?
You don't need to prepare for this test. Be sure your healthcare provider knows about
all medicines, herbs, vitamins, and supplements you are taking. This includes medicines
that don't need a prescription and any illicit drugs you may use.