Free Androgen Index
Does this test have other names?
What is this test?
A free androgen index (FAI) is a ratio figured out after a blood test for testosterone.
It's used to see whether you have abnormal androgen levels.
Both men and women make male hormones called androgens, which include testosterone.
During puberty, testosterone helps children develop into adults. As you age, levels
of this hormone can fall. This causes health problems for both men and women.
A testosterone test is a blood test that measures total testosterone, free testosterone,
and a protein called steroid hormone binding globulin (SHBG). A free androgen index
measures testosterone in your blood and compares it with the total amount of testosterone
and SHBG in your body.
Why do I need this test?
You may need this test if you show signs of abnormal androgen levels, which differ
in women and men.
These hormones aid in the development of sex organs and other gender-linked traits.
For example, androgens play a role in making the female hormone estrogen. When a woman
makes too many androgen hormones, she may develop extra body and facial hair. With
too little androgen hormones, a woman may become very tired, lose bone mass, or have
little interest in sex.
If you are a woman, you may have this test if you have extra hair on your body or
face. It's possible that unusual hair growth stems from an ovarian tumor or a condition
called polycystic ovarian syndrome (PCOS). Among other things, PCOS causes your ovaries
to make too much testosterone. Other symptoms of PCOS include obesity, an irregular
menstrual cycle, and prediabetes or diabetes.
Testosterone helps boys develop male traits, and makes facial hair in men. If an adolescent
boy isn't developing normally, certain organs might not be making enough of this hormone.
Adult men who don't make enough testosterone may feel weak, lose muscle strength and
mass, develop breasts, or lose interest in sex.
What other tests might I have along with this test?
Your healthcare provider may also order these tests:
If you are a woman, you may also get these tests:
Ferriman-Gallwey scale to measure whether you have an unusual amount of body hair
24-hour determination of urinary free cortisol for Cushing syndrome, a condition that
often causes excessive body hair
Dehydroepiandrosterone sulfate, or DHEA-S, a marker for an adrenal source of androgens
ACTH stimulation of 17-OHP, if your 17-OHP level is not clearly normal
Ovarian ultrasound to find out if you have an ovarian tumor
Adrenal CT scan to check for an adrenal tumor or other abnormalities
What do my test results mean?
Test results may vary depending on your age, gender, health history, the method used
for the test, and other things. Your test results may not mean you have a problem.
Ask your healthcare provider what your test results mean for you.
Test results also vary by age, gender, and overall health. Approximate normal FAI
values generally range between 30 and 150 in men. Levels below 30 mean a possible
testosterone deficiency. Women generally have FAI values of 7 to 10. Approximate normal
ranges of serum testosterone for adults are listed below.
If you are male and your level of total testosterone falls below 200 ng/dL, you may
be diagnosed with hypogonadism. This is an androgen deficiency that causes testosterone
levels to drop.
Your hormone levels may be affected by a temporary health condition, such as pregnancy.
You may also have results that aren't clear and need to be retested.
How is this test done?
The test is done with a blood sample. A needle is used to draw blood from a vein in
your arm or hand.
Does this test pose any risks?
Having a blood test with a needle carries some risks. These include bleeding, infection,
bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may
feel a slight sting or pain. Afterward, the site may be sore.
What might affect my test results?
If you are pregnant, your ovaries may make too much testosterone as part of a normal
pregnancy. Having a tumor or cyst in your ovaries or adrenal gland can also cause
your testosterone level to rise.
People with Cushing syndrome may also have higher levels of testosterone.
Certain medicines can affect hormone production, including some steroids and opiates.
Let your healthcare provider know about any prescription medicine you take.
How do I get ready for this test?
You don't need to prepare for this test. Be sure your healthcare provider knows about
all medicines, herbs, vitamins, and supplements you are taking. This includes medicines
that don't need a prescription and any illicit drugs you may use.