Does this test have other names?
Serum myoglobins, myoglobin-serum
What is this test?
This test measures the amount of a protein called myoglobin in your blood. It's done
to help diagnose conditions caused by muscle damage.
Myoglobin is found in your heart and skeletal muscles. There it captures oxygen that
muscle cells use for energy. When you have a heart attack or severe muscle damage,
myoglobin is released into your blood.
Myoglobin increases in your blood 2 to 3 hours after the first symptoms of muscle
damage. It usually peaks about 8 to 12 hours later.
Your kidneys filter your blood for myoglobin so that it can be passed out of your
body in your urine. But too much myoglobin can overwhelm your kidneys and lead to
kidney failure. In some cases, healthcare providers will use a urine test for myoglobin
to help find the problem and protect your kidney health.
Why do I need this test?
You may need this test if you have a severe muscle injury, such as with trauma or
a condition that damages muscle. Symptoms of muscle injury or damage include:
Nausea and vomiting
You may also have this test if your healthcare provider suspects you have had a heart
attack, which causes damage to the heart muscle. This test may be done every 2 or
3 hours if you go to the emergency room with chest pain or other symptoms of a heart
This test will help your healthcare provider find out whether your injuries need treatment
right away. If your myoglobin level rises too high, you may have to get intravenous
fluids or other treatments to help flush the extra myoglobin out of your body.
What other tests might I have along with this test?
Higher myoglobin levels can mean that your muscles have been damaged. If your healthcare
provider suspects muscle damage, they may order other tests to check the following:
Complete blood count, including a differential and platelet count
Blood urea nitrogen, creatinine, and routine electrolytes, including potassium
Calcium, phosphate, albumin, and uric acid
A myoglobin test is not considered the most specific for diagnosing a heart attack.
But if your provider thinks your heart has been damaged from a heart attack, they
may order tests to confirm it. These include:
Blood tests for other heart attack markers. These tests will look at troponin and other substances that may be released when your
heart is damaged.
Electrocardiogram. This test is done to watch your heart's electrical impulses.
Imaging tests. Various scans can check your heart for damage, clots, and other problems that may
affect its ability to pump your blood.
What do my test results mean?
Test results may vary depending on your age, gender, health history, and other things.
Your test results may be different depending on the lab used. They may not mean you
have a problem. Ask your healthcare provider what your test results mean for you.
Results are given in micrograms per liter (mcg/L). Normal results are 5 to 70 mcg/L.
Higher myoglobin levels mean that you may have muscle damage, but they don't show
where the damage took place. Your healthcare provider will likely order other tests
to confirm where the damage is.
Muscles can be injured in many ways, including:
Coma or another situation in which you don't move for a long period of time
Poisons and certain medicines
Conditions, such as muscular dystrophy
Unusually strenuous exercise
Higher results may also be caused by:
Lower results may mean you have:
How is this test done?
The test is done with a blood sample. A needle is used to draw blood from a vein in
your arm or hand.
Does this test pose any risks?
Having a blood test with a needle carries some risks. These include bleeding, infection,
bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may
feel a slight sting or pain. Afterward, the site may be sore.
What might affect my test results?
Cocaine and heavy alcohol use can affect your results. So, too, can certain medicines.
How do I get ready for this test?
You don't need to prepare for this test. Be sure your healthcare provider knows about
all medicines, herbs, vitamins, and supplements you are taking. This includes medicines
that don't need a prescription and any illegal drugs you may use.