Toxoplasma Gondii Antibody
Does this test have other names?
Immunoglobulin G antibodies, immunoglobulin M antibodies, Sabin-Feldman dye test,
IFA test, EIA test
What is this test?
This test looks for antibodies against Toxoplasma gondii (T. gondii) infection in
T. gondii is a parasite that can infect people when they:
Eat infected meat, especially lamb, venison, or pork, that hasn't been fully cooked
Eat food contaminated by knives, utensils, cutting boards, or other foods that have
come in contact with the infected meat
Drink contaminated water
Swallow the parasite after being exposed to it while cleaning an infected cat's litter
In healthy adults, this infection often doesn’t cause any symptoms. But in people
whose immune system isn't working well, a T. gondii infection can cause brain damage
and other serious problems. If a pregnant person is infected, it can cause stillbirth,
severe birth defects, or problems that can be seen in the child years later.
Why do I need this test?
You may need this test if your healthcare provider thinks that you have toxoplasmosis.
Most people who are infected with T. gondii don’t know it. Symptoms can include:
Flu-like symptoms, such as achiness and swollen lymph nodes
Blurry vision, eye redness, and pain if the disease is affecting the eyes
A small number of infected infants have brain or eye damage at birth.
If you're pregnant, you may also have this test, especially if you may have been exposed
to T. gondii.
What do my test results mean?
Test results may vary depending on your age, gender, health history, and other things.
Your test results may be different depending on the lab used. They may not mean you
have a problem. Ask your healthcare provider what your test results mean for you.
Test results can show if you have higher levels of immunoglobulin G (IgG) or immunoglobulin
M (IgM) antibodies that are related to T. gondii infection. IgM antibodies tend to
show up faster and go away faster after an infection. IgG antibodies tend to slowly
go away over the next 1 to 2 years.
The results can tell your healthcare provider if you have a new infection or had an
infection in the past.
How is this test done?
The test is done with a blood sample. A needle is used to draw blood from a vein in
your arm or hand.
Does this test pose any risks?
Having a blood test with a needle carries some risks. These include bleeding, infection,
bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may
feel a slight sting or pain. Afterward, the site may be sore.
What might affect my test results?
If you have AIDS and toxoplasmosis, you may have only a small rise in IgG. In this
case, the results for IgM and other antibodies may show up as negative. Other factors
aren't likely to affect your results.
How do I get ready for this test?
Tell your healthcare provider if you have a condition that affects your immune system
or are taking any medicines that may do so. It's best to be sure your provider knows
about all the medicines, herbs, vitamins, and supplements you are taking. This includes
medicines that don't need a prescription and any illegal drugs you may use.