Does this test have other names?
What is this test?
This test measures levels of trypsin in your blood to see if you have pancreatitis.
Your pancreas is an organ in your belly (abdomen). It lies behind your stomach. One
of its jobs is to make enzymes that go into your small intestine to help you digest
foods. The pancreas can become inflamed (pancreatitis). This can occur suddenly (acute
pancreatitis). Or it can grow worse over a longer time (chronic pancreatitis).
During acute pancreatitis, enzymes from your pancreas can escape into your blood.
One of these enzymes is trypsin. It's made from trypsinogen. Trypsinogen turns into
trypsin in the small intestine, and the names of the two are sometimes used interchangeably.
Why do I need this test?
You might have this test if your healthcare provider suspects that you have pancreatitis.
Symptoms of acute pancreatitis include:
Pain in your upper abdomen that can come on quickly and last for days. The pain may
be severe, and it may travel to your back. Leaning forward may relieve the pain.
Nausea and vomiting, which can last for hours
Chronic pancreatitis can cause many of the same symptoms, as well as some that are
different. They include:
Pain that is often worse just after you eat. It may strike in flare-ups early in the
disease and later become steadier.
Oily, foul-smelling stools because of problems absorbing fat from foods
Glucose intolerance or diabetes
Heavy alcohol use over time can cause pancreatitis, as can certain types of medicines.
What other tests might I have along with this test?
Your healthcare provider may also order a number of other tests if you have symptoms
of pancreatitis. Tests for acute pancreatitis may include measurements of:
Amylase, another kind of pancreatic enzyme, which may be in your blood or urine
Lipase, another pancreatic enzyme found in your blood
Other substances in your blood that point to inflammation, including C-reactive protein
Other tests for chronic pancreatitis may include:
What do my test results mean?
Many things may affect your lab test results. These include the method each lab uses
to do the test. Even if your test results are different from the normal value, you
may not have a problem. To learn what the results mean for you, talk with your healthcare
Higher levels of trypsin can mean that you have acute pancreatitis.
How is this test done?
The test requires a blood sample, which is drawn through a needle from a vein in your
Does this test pose any risks?
Taking a blood sample with a needle carries risks that include bleeding, infection,
bruising, or feeling dizzy. When the needle pricks your arm, you may feel a slight
stinging sensation or pain. Afterward, the site may be slightly sore.
What might affect my test results?
Other factors aren't likely to affect your results.
How do I get ready for this test?
You don't need to prepare for this test. But be sure your healthcare provider knows
about all medicines, herbs, vitamins, and supplements you are taking. This includes
medicines that don't need a prescription and any illicit drugs you may use.