What is osteomyelitis?
Osteomyelitis is an inflammation or swelling of bone tissue. It’s most often caused
by an infection. Bone infection may occur for many reasons and can affect children
What causes osteomyelitis?
Osteomyelitis can be caused by a bacterial infection of the blood. This is sometimes
called bacteremia or sepsis. This infection can spread to the bone. It’s most common
in infants and children and usually affects their long bones such as the thighbone
or upper arm bone. When it affects adults, it often involves the bones in the spine.
The source of the blood infection is usually Staphylococcus aureus, although it may be caused by other organisms.
Other causes include:
- After an injury or surgery
- Having frequent medicine injections
- Having diabetes
- Having a weak immune system (such as HIV or getting cancer treatment)
- Using a prosthetic device
Osteomyelitis can have a sudden start, a slow and mild start, or may be a chronic
problem, depending on the source of the infection.
Who is at risk for osteomyelitis?
Osteomyelitis can affect anyone. But, it is more common in infants, children, and
older adults. People at greater risk include those with weak immune systems, recent
injury, or diabetes.
What are the symptoms of osteomyelitis?
Symptoms of osteomyelitis vary, depending on the cause and whether it starts quickly
or slowly. These are the most common:
- A new limp
- A stiff back, if the spine is affected
- Feeling ill
- Fever (high fever with blood infection)
- Pain and tenderness in the affected area
- Redness in the affected area
- Swelling of the affected area
- Trouble bearing weight or walking
- Trouble moving joints near the affected area
- Warmth in the affected area
The symptoms of osteomyelitis may look like other medical conditions or problems.
Always talk with your healthcare provider for a diagnosis.
How is osteomyelitis diagnosed?
Your healthcare provider will review your medical history and do a physical exam.
Other tests may include:
- Blood tests, such as:
- Complete blood count (CBC). This test measures the size, number, and maturity of blood cells. It’s done to check
for increased white blood cells that may signal an infection.
- Erythrocyte sedimentation rate (ESR). This test measures how quickly red blood cells fall to the bottom of a test tube.
When swelling and inflammation are present, the blood’s proteins clump together and
become heavier than normal. So, they fall and settle faster at the bottom of the test
tube. Generally, the faster the blood cells fall, the more severe the inflammation.
- C-reactive protein (CRP). A blood test to help find inflammation or an infection.
- Needle aspiration or bone biopsy. A small needle is inserted into the affected area to take a tissue biopsy.
- X-ray. This test uses invisible electromagnetic energy beams to make images of tissues, bones,
and organs onto film.
- Radionuclide bone scans. Pictures or X-rays are taken of the bone after a dye is injected and absorbed by the
bone tissue. These are used to find tumors and bone abnormalities.
- CT scan. This test uses X-rays and a computer to make images (often called slices) of the body.
A CT scan shows detailed images of any part of the body, including the bones, muscles,
fat, and organs. CT scans are more detailed than general X-rays.
- MRI. This test uses large magnets, radiofrequencies, and a computer to make detailed images
of organs and structures in the body.
- Ultrasound. This test uses high frequency sound waves and a computer to make images of blood vessels,
tissues, and organs. Ultrasounds are used to view organs as they work, and to check
blood flow through blood vessels.
How is osteomyelitis treated?
Your healthcare provider will figure out the best treatment for you based on:
- How old you are
- Your overall health and past health
- How sick you are
- How well you can handle specific medicines, procedures, or therapies
- How long the condition is expected to last
- Your opinion or preference
The goal for treatment of osteomyelitis is to cure the infection and minimize any
long-term problems. Treatment may include:
- Medicines. You may be give IV antibiotics. This often means a hospital stay. Or you may be given
antibiotics as an outpatient. In either case, treatment may last for many weeks.
- X-rays and blood tests. Your healthcare provider will monitor your test results.
- Pain management. You will get medicine to manage your pain.
- Bed rest. You may need to limit movement of the affected area.
- Surgery. In some cases, surgery may be needed to drain fluid, or remove damaged tissue and
What are the complications of osteomyelitis?
Osteomyelitis calls for long-term care to prevent complications such as:
- Fractures of the affected bone
- Stunted growth in children, if the infection has involved the growth plate
- Tissue death (gangrene) in the affected area
Key points about osteomyelitis
- Osteomyelitis is an inflammation or swelling of bone tissue. It’s most often the result
of an infection. It can affect all people, but is more common in infants, children,
and older adults.
- Causes of osteomyelitis include: bacterial infection in the blood, having an injury
or surgery, having frequent medicine injections, having diabetes or a weak immune
system, and using a prosthetic device.
- The goal for treatment of osteomyelitis is to cure the infection and minimize any
- Osteomyelitis calls for long-term care to prevent complications.
Tips to help you get the most from a visit to your healthcare provider:
- Know the reason for your visit and what you want to happen.
- Before your visit, write down questions you want answered.
- Bring someone with you to help you ask questions and remember what your healthcare
provider tells you.
- At the visit, write down the name of a new diagnosis, and any new medicines, treatments,
or tests. Also write down any new instructions your healthcare provider gives you.
- Know why a new medicine or treatment is prescribed, and how it will help you. Also
know what the side effects are.
- Ask if your condition can be treated in other ways.
- Know why a test or procedure is recommended and what the results could mean.
- Know what to expect if you do not take the medicine or have the test or procedure.
- If you have a follow-up appointment, write down the date, time, and purpose for that
- Know how you can contact your healthcare provider if you have questions.